A case of acquired hemophilia A and bullous pemphigoid following SARS-CoV-2 mRNA vaccinationArticle Published on 2022-09-012022-11-15 Journal: Journal of the Formosan Medical Association = Taiw [Category] SARS, 진단, [키워드] Acquired acquired hemophilia Acquired hemophilia A activated AHA autoantibody Autoimmunity bleeding Blister bullous bullous pemphigoid Characteristics Diagnosis environmental factor epithelial FVIII Genetic hemophilia Hemorrhagic high mortality rate immune tolerance inhibitor Isolated membrane Moderna mRNA mRNA vaccination mRNA vaccine mRNA vaccine. pathophysiology pemphigoid rare disease recent reported resulting SARS-CoV-2 supported vaccination zone [DOI] 10.1016/j.jfma.2022.02.017 PMC 바로가기
How does age determine the development of human immune-mediated arthritis? Reviews Published on 2022-08-102022-10-05 Journal: Nature reviews. Rheumatology [Category] 유전자 메커니즘, 진단, [키워드] Adults Affect age Arthritis autoantibody children chronic inflammation contribute controls Critical determine develop disease driven by Drivers environmental exposure Epigenetic expand facilitate Factor Factors Genetic genetics hypothese immune immune system immune tolerance Immune-mediated individual Inflammation involved juvenile idiopathic arthritis maturation mechanism mechanisms microbial modulation Numerous Pathogenesis Patient Phenotypes pro-inflammatory similarity tolerogenic [DOI] 10.1038/s41584-022-00814-3 [Article Type] Reviews
Capabilities of hepatitis B surface antigen are divergent from hepatitis B virus DNA in delimiting natural history phases of chronic hepatitis B virus infectionArticle Published on 2022-07-252023-06-12 Journal: Frontiers in Immunology [Category] B형 간염, Fulltext, [키워드] Chronic HBV infection hepatitis B surface antigen immune tolerance locally estimated scatter plot smoothing regression natural history stratified analysis. [DOI] 10.3389/fimmu.2022.944097 PMC 바로가기
Innate and adaptive immune escape mechanisms of hepatitis B virusReview Published on 2022-03-072023-06-09 Journal: World journal of gastroenterology [Category] B형 간염, [키워드] Adaptive immunity Hepatitis B virus immune tolerance Innate immunity therapeutic strategy. [DOI] 10.3748/wjg.v28.i9.881 PMC 바로가기 [Article Type] Review
Does the Fetus Limit Antibiotic Treatment in Pregnant Patients with COVID-19?Article Published on 2022-02-162022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] Acinetobacter adverse effect Alter Antibiotic treatment Antibiotics Bacterial coinfection bacteriological circulation Clostridium difficile COVID-19 Culture diagnosed dihydrofolate drug drugs during pregnancy Enterococcus faecium ESBL Escherichia coli Evidence fetal fetus generate Hospitalized immune tolerance inhibitors malformation microbiota mortality rate patients Placenta Pregnancy pregnant women Prevent Protective SARS-CoV-2 significantly Staphylococcus Staphylococcus epidermidis Streptococcus the timing Treatment turn use of antibiotics viral infection was performed with COVID-19 [DOI] 10.3390/antibiotics11020252 PMC 바로가기 [Article Type] Article
Hypothesis: Emerging Roles for Aryl Hydrocarbon Receptor in Orchestrating CoV-2-Related Inflammation †Review Published on 2022-02-132022-10-31 Journal: Cells [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] ACE-2 adaptive angiotensin Apoptosis aryl Aryl hydrocarbon receptor AT1 binding boost build COVID-19 disease enzyme expression growth hydrocarbon IFN-I IL-6 immune tolerance Immunity Indolamine induce Inflammation Inflammatory Inflammatory response inflammatory state inhibitory innate response interferon Kynurenine limit management mechanism modulation Neutral pathogenic regulate respiratory Respiratory system role SARS-CoV-2 syndrome T cell target therapeutic target These data transporter Tryptophan type I [DOI] 10.3390/cells11040648 PMC 바로가기 [Article Type] Review
K63 ubiquitination in immune signalingReview Published on 2022-02-012023-07-07 Journal: Trends in immunology [Category] COVID19(2023년), [키워드] E3 ligase immune response immune tolerance K63-linked ubiquitination pattern recognition receptor (PRR) SARS-CoV-2 Ubc13 ubiquitin. [DOI] 10.1016/j.it.2021.12.005 PMC 바로가기 [Article Type] Review
The etiology of preeclampsiaReview article Published on 2022-02-012022-10-05 Journal: American journal of obstetrics and gynecology [Category] 비임상, [키워드] activate Activation angiotensin receptor II association Atherosclerosis autoantibodies Autoimmunity Ballantyne syndrome body mass index COVID-19 Cushing’s syndrome disease Diseases disorder Endocrine Endothelial cell endothelial cell dysfunction etiology experimental evidence Factor Factors fetal genetic incompatibility gestational diabete gestational diabetes mellitus greater Gut hydatidiform mole hydrops fetalis hyperaldosteronism hyperparathyroidism hypertension immune tolerance IMPROVE Infection Inflammation insulin resistance intestinal dysbiosis involved Ischemia maternal antifetal rejection metabolic syndrome microorganism mirror syndrome molar pregnancy obesity overlapping Particular pathologic processe pathway Patient placental placental aging placental ischemia placental lesions of maternal vascular malperfusion potential mechanism preeclampsia primipaternity Proteinuria SARS-CoV-2 SARS-COV-2 infection sleep disorders sleep-disordered breathing snoring Stress subset thought Tolerance Treatment [DOI] 10.1016/j.ajog.2021.11.1356 [Article Type] Review article
The Different Immune Responses by Age Are due to the Ability of the Fetal Immune System to Secrete Primal Immunoglobulins Responding to Unexperienced Antigens연령에 따른 다른 면역 반응은 미숙한 항원에 반응하는 원시 면역글로불린을 분비하는 태아 면역 체계의 능력 때문입니다Research Paper Published on 2022-01-012022-09-10 Journal: International Journal of Biological Sciences [Category] SARS, 유전자 메커니즘, [키워드] Ability acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity age aging analyzed antibody Antigen Antiviral antiviral proteins Birth cells complement component components condition conditions coronavirus Coronavirus 2019 COVID-19 Critical Culture decrease demonstrated early pregnancy environmental factor EVs extracellular vesicle Extracellular vesicles Factor fetal fetal immune system form FSC HLA-G human leukocyte antigen Hypothesis IgG3 IgM immune reaction immune system immune systems immune tolerance Immunoglobulin immunoglobulin M immunoglobulins independent Infection Infectious disease Infectious diseases leukocyte mechanism mortality rate mutations NAbs natural antibody Pregnancy produced Protein Proteins respiratory Responding response responsible SARS-CoV-2 severe acute respiratory syndrome Coronavirus stem cell stem cells susceptible System [DOI] 10.7150/ijbs.67203 PMC 바로가기 [Article Type] Research Paper
Acute estradiol and progesterone therapy in hospitalised adults to reduce COVID-19 severity: a randomised control trialRandomized Controlled Trial Published on 2021-11-302022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] addition Admission adverse events Anti-inflammatory antibody production approved drug Biology center clinically Corticosteroids COVID-19 death determine disease severity double blind drug Efficacy Ethical approval Ethics evaluate food general endocrinology Hospital stay hospitalised Hospitalised patients HRT HRT. immune response immune tolerance include Infectious diseases Inflammatory biomarker intramuscular mechanical ventilation Medicine mitigate New New Orleans Occurrence Oestradiol outcome Participants Patient peer-reviewed Phase 2 Placebo placebo-controlled primary endpoint Primary outcome progesterone proportion randomised readmission reduce reducing Result Sample size secondary Sex sex steroids & Sponsor Standard of care steroid subjects submitted the WHO therapeutic option therapy Trial university USA was obtained WHO ordinal scale [DOI] 10.1136/bmjopen-2021-053684 PMC 바로가기 [Article Type] Randomized Controlled Trial