Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing homearticle Published on 2023-03-062024-09-05 Journal: Immunity & Ageing : I & A [Category] update2024, [키워드] antibody waning BNT162b2 vaccine Immunesenescence inflammaging Magnitude and persistence of humoral response nursing home RTL Sj/β-TRECs ratio Thymic-function Thymosin-α1 [DOI] 10.1186/s12979-023-00334-y PMC 바로가기 [Article Type] article
Individual Factors Including Age, BMI, and Heritable Factors Underlie Temperature Variation in Sickness and in Health: An Observational, Multi-cohort StudyObservational Study Published on 2022-09-012022-10-04 Journal: The Journals of Gerontology Series A: Biological S [Category] SARS, 임상, [키워드] 95% confidence interval ACE acute infection Admission Affect age aging Analysis association basal BMI body mass index characteristic Community-based cohort contribute COVID COVID-19 COVID-19 infection Effect examined Factor Fever Genetic Health healthy heritability hospital identify Immunesenescence Immunity Including increasing age individual Infection less Linear regression London multivariable multivariable logistic regression observation Older participant Participants positive RT-PCR ROC RT-PCR SARS-CoV-2 SARS-COV-2 infection saturated Sensitivity and specificity Sex temperature temperature regulation Thermoregulation threshold TwinsUK variable volunteers was used [DOI] 10.1093/gerona/glab295 PMC 바로가기 [Article Type] Observational Study
Immunesenescence: A Predisposing Risk Factor for the Development of COVID-19?Immunology Published on 2020-10-062022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] accelerated activated acute respiratory syndrome advanced age aging Bearing characterized co-morbidity coronavirus Coronavirus disease 2019 COVID-19 COVID-19 treatment demographic group described development dysregulated effective exacerbate Factor feature females functional Gender group high risk highlight immune dysfunction Immune profile immune response immune system Immunesenescence inflammaging Inflammatory less Lymphocytes male Monocytes obese obesity occur Older pathogen patients phenotypic Premature question response risk factor SARS-Cov_2 SARS-CoV-2 senescent severe COVID-19 subject susceptibility T cells T2D therapeutic options Treatment type 2 diabete [DOI] 10.3389/fimmu.2020.573662 PMC 바로가기 [Article Type] Immunology
Reversing the immune ageing clock: lifestyle modifications and pharmacological interventionsReview Article Published on 2018-09-292024-09-02 Journal: Biogerontology [Category] 대상포진, [키워드] Ageing Immunesenescence inflammaging [DOI] 10.1007/s10522-018-9771-7 PMC 바로가기 [Article Type] Review Article