Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategiesReview Published on 2023-12-192024-09-05 Journal: Human vaccines & immunotherapeutics [Category] update2024, [키워드] COVID-19 vaccine immune response immunization strategies [DOI] 10.1080/21645515.2023.2273155 PMC 바로가기 [Article Type] Review
Characterization of SARS-CoV-2 Escape Mutants to a Pair of Neutralizing Antibodies Targeting the RBD and the NTDRBD 및 NTD를 표적으로 하는 한 쌍의 중화 항체에 대한 SARS-CoV-2 탈출 돌연변이의 특성화Article Published on 2022-07-252022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] active immunization Affect antibodies antibody binding Cell culture characterization Clinical use Cluster Combination Efficacy escape escape mutant escape mutants escape mutation gene segments Genetic human immunoglobulin identify immunization immunization strategies Immunoglobulin indicate lead mice monoclonal monoclonal antibodies monoclonal antibody more difficult Mutation mutations neutralization Neutralization assay Neutralizing Neutralizing antibodies neutralizing antibody neutralizing monoclonal antibodies neutralizing monoclonal antibody nine not affected NTD pair passage pseudotype RBD RBD mutations reduced SARS-CoV-2 SARS-CoV-2 escape mutations SARS-CoV-2 variant SARS-CoV-2 variants selected Spike protein targeting the RBD the spike protein variable region variant variants variants of concern VoC [DOI] 10.3390/ijms23158177 PMC 바로가기 [Article Type] Article
Six-month follow-up of a booster dose of CoronaVac in two single-centre phase 2 clinical trials2개의 단일 센터 2상 임상 시험에서 CoronaVac의 추가 용량의 6개월 추적Clinical Trial Published on 2022-06-032022-09-12 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] adverse event age Antibody titre booster booster dose clinical trial clinical trials contribute CoronaVac Determining dose double-blind Exploratory endpoints Follow-up follow-up period geometric mean titre GMT GMTs homologous humoral Immunity immunization immunization strategies increases in magnitude neutralising antibody neutralization Older placebo-controlled population immunity post-hoc analyses randomised recommendation recorded regimen Secondary endpoints titre [DOI] 10.1038/s41467-022-30864-w PMC 바로가기 [Article Type] Clinical Trial
Strategies and safety considerations of booster vaccination in COVID-19COVID-19에서 추가 백신 접종의 전략 및 안전 고려 사항Review Published on 2022-06-012022-09-11 Journal: Bosnian Journal of Basic Medical Sciences [Category] Coronavirus, COVID19(2023년), SARS, 변종, [키워드] addition approaches booster booster vaccination breakthrough infections combination vaccine COVID-19 COVID-19 pandemic Diseases Effectiveness Efficacy groups Heterologous homologous Immune escape immunization strategies Immunocompromised persistence priority Protective reducing mortality SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2 variant SARS-CoV-2 variants Strategy vaccination Vaccine [DOI] 10.17305/bjbms.2021.7082 PMC 바로가기 [Article Type] Review
BNT162b2 Vaccine-Associated Myo/Pericarditis in Adolescents: A Stratified Risk-Benefit AnalysisBNT162b2 청소년의 백신 관련 근/심낭염: 계층화된 위험-이점 분석Article Published on 2022-05-012022-09-11 Journal: European Journal of Clinical Investigation [Category] COVID19(2023년), SARS, 변종, [키워드] Adverse adverse effect age Analysis benefit BNT162b2 carried CDC criteria children Cohort Comorbidities Comorbidity COVID-19 COVID-19 hospitalization COVID-19 vaccination dose drug-related adverse reactions elevated estimates Health status Hospitalized immunization strategies immunization strategy implication incidence Infection International male mRNA mRNA vaccination myocarditis Occurrence omicron outcome paediatrics Patient performed Pericarditis population level Protective reduce Reporting risk Risk-benefit analysis SARS-CoV-2 SARS-COV-2 infection second dose severe disease Sex Support System vaccination variant Weighing [DOI] 10.1111/eci.13759 PMC 바로가기 [Article Type] Article
SARS-CoV-2 vaccine research and immunization strategies for improved control of the COVID-19 pandemicCOVID-19 전염병의 통제를 개선하기 위한 SARS-CoV-2 백신 연구 및 예방 접종 전략Review Published on 2022-04-012022-09-11 Journal: Frontiers of medicine [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus 2 booster dose Chinese Combination coronavirus 2 coronavirus disease Coverage COVID-19 COVID-19 pandemic develop diagnostics drugs effective vaccine Effective vaccines effort facilitated genomic sequence herd immunity Herd immunity threshold homologous homologous or heterologous immune protection immunization strategies immunization strategy immunize multidimensional Older pandemic Pandemics population immunity regulatory agencies regulatory agency Research SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants Scientific community Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus vaccination Vaccination strategies Vaccine vaccine immunity Vaccines virus variant virus variants [DOI] 10.1007/s11684-021-0913-y PMC 바로가기 [Article Type] Review
Analysis of COVID-19 Risk Following a Ring Vaccination Intervention to Address SARS-CoV-2 Alpha Variant Transmission in Montreal, Canada캐나다 몬트리올에서 SARS-CoV-2 알파 변종 전파를 해결하기 위한 링 백신 개입 후 COVID-19 위험 분석Research Published on 2022-02-112022-09-10 Journal: JAMA Network Open [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] 95% CI address adjunct age Alpha Alpha variant analyzed association Canada children close contact cohort study confirmed case confirmed cases Contact contact with control group Coverage COVID-19 COVID-19 incidence COVID-19 infection COVID-19 vaccine defined disease risk dose Epidemiology exposure finding group groups highest immunization immunization strategies immunization strategy immunized implementation Importance Infection initial Intervention intervention group introduced Local mass immunization measure Montreal Montreal, Canada mRNA vaccine objective outbreak pandemic parent parents participant Point reached receive reduction in Relevance respiratory respiratory viruses Result Ring risk risk of COVID-19 risk ratio SARS-CoV-2 SARS-CoV-2 transmission SARS-CoV-2 variant SARS-CoV-2 variants School setting significantly higher Spread Transmission vaccination Vaccine variant [DOI] 10.1001/jamanetworkopen.2021.47042 PMC 바로가기 [Article Type] Research
Seroconversion rates following COVID-19 vaccination among patients with cancer암환자의 코로나19 예방접종 후 혈청전환율Article Published on 2021-08-092022-09-12 Journal: Cancer cell [Category] MERS, SARS, 진단, [키워드] Affect anti-CD20 therapy anti-Spike IgG antibody Cancer Cohort COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccines demonstrated hematologi malignancies Hematologic malignancy hormonal therapy identify IgG titer immune immunization strategies Immunosuppressed immunosuppressive therapy inhibitor mRNA-based vaccines New York City oncology patient Patient Patients with cancer post vaccination prophylactic strategy rate of seroconversion receiving recipient SARS-CoV-2 spike protein Seroconversion seroconversion rate significantly lower solid tumor Stem cell transplantation therapy vaccination Vaccine [DOI] 10.1016/j.ccell.2021.06.002 PMC 바로가기 [Article Type] Article
Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range비강 점막의 면역 세포 거주는 연령대의 호흡기 질환 심각성을 부분적으로 설명 할 수 있습니다.Article Published on 2021-08-052022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, [키워드] Adults age analyzed antiviral properties applied Cell cell type cellular changes in children correlated COVID-19 severity epigenome epithelial cell epithelial cells Evidence explain Functional genomics generate healthy individual healthy individuals immune immune activation Immune cell immune cell type immunization strategies individual infection with SARS-CoV-2 innate immune response innate immune system Mucosal immunology nasal nasal mucosa Previous studies previous study proportion reflect resource respiratory Respiratory disease respiratory infection robust SARS-CoV-2 Sequencing severity Single-cell RNA-sequencing suggested T cell transcriptional underlie uninfected [DOI] 10.1038/s41598-021-95532-3 PMC 바로가기 [Article Type] Article
Brief review of the mRNA vaccines COVID-19mRNA 백신 COVID-19에 대한 간략한 검토Review Published on 2021-06-012022-09-11 Journal: Inflammopharmacology [Category] SARS, 변종, [키워드] COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines defined DNA vaccine effective Health highlight Immunity immunization strategies inactivated indicated mRNA mRNA vaccine mRNA vaccines organ damage Pharmacology Preventive medicine Protein subunit representing safety profile SARS-CoV-2 variants serious complication therapeutic agent therapeutic agents treat vaccination Vaccine Viral vector virus [DOI] 10.1007/s10787-021-00811-0 PMC 바로가기 [Article Type] Review