Immunoglobulin yolk targeting spike 1, receptor binding domain of spike glycoprotein and nucleocapsid of SARS-CoV-2 blocking RBD-ACE2 binding interactionArticle Published on 2022-11-012022-11-15 Journal: International immunopharmacology [Category] SARS, 진단, [키워드] ACE2 acute respiratory syndrome Angiotensin-converting-enzyme-2 binding binding interaction blocking virus entry Brown caused characterized coronavirus demonstrated disease ELISA enzyme-linked immunosorbent evaluate evaluated feasible global pandemic immunization immunized Immunoglobulin immunoglobulin Y in vitro Infection inhibit kDa Laying Laying hens molecular weight Neutralizing nucleocapsid purified RBD RBD-ACE2 Receptor binding domain Receptor-binding-domain SARS-CoV-2 SDS-PAGE serum Specific spike glycoprotein [DOI] 10.1016/j.intimp.2022.109280 PMC 바로가기
Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19COVID-19에 대한 비강내 예방으로서 광범위한 변이 활성을 갖는 계란 유래 항-SARS-CoV-2 면역글로불린 Y(IgY)Clinical Trial Published on 2022-06-012022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] 2019 novel coronavirus 2019-nCoV activity Administered Against Alpha anti-SARS-CoV-2 Antiviral approval approvals B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta binding capture chicken immunoglobulin clinical clinical trial clinical trial body Clinical use contagiousness Convalescent patients COVID-19 cross-reactivity Delta demonstrated develop Diseases distribution double-blind effective Emergency use authorization enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Evidence evidence of greater healthy human tissue human tissues IgY Immunity immunized Immunoglobulin immunoglobulin Y index Infectious diseases intranasal intranasally multiple dose multiple doses nasal drop nasal drops nasal mucosa neutralization titer no evidence of Novel coronavirus omicron Phase 1 phase 1 study Placebo placebo-controlled Prevalence Prophylaxis raised Randomized RATs RBD Receptor-binding domain reduce reduced risk Safe safety profile SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 viral sensitivity sera Spike protein the receptor-binding domain the SARS-CoV-2 Tolerability Transmission Trial Vaccine Vaccine hesitancy variants variants of concern variety Viral virus [DOI] 10.3389/fimmu.2022.899617 PMC 바로가기 [Article Type] Clinical Trial
Immunoglobulin Y for Potential Diagnostic and Therapeutic Applications in Infectious DiseasesImmunology Published on 2021-06-092022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] animal model antibody antiparasitic drug application benefit chicken chicken immunoglobulin conserved Diseases Efficacy Health homolog Human human immunoglobulin IgG IgY Immunoglobulin immunoglobulin Y infections Infectious disease pathogen Potential safety profile shown Treatment Vaccine variety viral (or virus) [DOI] 10.3389/fimmu.2021.696003 PMC 바로가기 [Article Type] Immunology
Application of an immunoglobulin Y-alkaline phosphatase bioconjugate as a diagnostic tool for influenza A virusResearch Paper Published on 2019-03-272023-06-14 Journal: Bioengineered [Category] Fulltext, 신종인플루엔자, [키워드] alkaline phosphatase Diagnosis ELISA methods immunoglobulin Y influenza A [DOI] 10.1080/21655979.2019.1586054 PMC 바로가기 [Article Type] Research Paper
Production and characterization of a conserved M2e peptide-based specific IgY antibody: evaluation of the diagnostic potential via conjugation with latex nanoparticlesArticle Published on 2018-01-012023-05-31 Journal: Preparative biochemistry & biotechnology [Category] 신종인플루엔자, 조류인플루엔자, [키워드] Affinity chromatography Diagnosis immunoglobulin Y influenza A latex agglutination latex nanoparticles. [DOI] 10.1080/10826068.2018.1525564
Comparing Antibody Responses in Chickens Against Plasmodium falciparum Lactate Dehydrogenase and Glyceraldehyde-3-phosphate Dehydrogenase with Freund’s and Pheroid® Adjuvantsarticle Published on 2015-12-312024-09-01 Journal: Immunological Investigations [Category] 말라리아, [키워드] adjuvant Freund's glyceraldehyde-3-phosphate dehydrogenase immunoglobulin Y lactate dehydrogenase malaria Pheroid® Plasmodium falciparum [Article Type] article