As the virus evolves, so too must we: a drug developer’s perspective : We need a new paradigm in searching for next-generation countermeasuresArticle Published on 2022-10-102022-11-15 Journal: Virology Journal [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] addition antibody Antiviral approach cellular immunity COVID19 develop drug drug resistance drugs Effect effective Evolution of SARS-CoV-2 Genetic greater HAD HDTx host-directed antiviral Host-directed therapeutics humoral immune immune evasion in sight infections offer omicron Pandemic countermeasures Perspective plasticity population immunity Quasispecies recombinant reduce risk SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 virus selective severity strain Treatment Vaccine variant variants virus [DOI] 10.1186/s12985-022-01887-y PMC 바로가기
Optimizing antiviral therapy for COVID-19 with learned pathogenic model학습된 병원성 모델로 COVID-19에 대한 항바이러스 요법 최적화Article Published on 2022-04-272022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 신약개발, 임상, 치료기술, 치료법, 치료제, [키워드] Antiviral antiviral therapy antivirals caused Clinical data clinical trial clinical trials COVID-19 cure dose Efficacy fatality followed by healthcare Healthcare industry immune in sight Mental multi multitude Pathogenesis pathogenesis of SARS-CoV-2 pathogenic predict reduction in Remdesivir schedule severe COVID-19 patient severe COVID-19 patients sight T cell T cells therapy toxicities treated variant variants Virological [DOI] 10.1038/s41598-022-10929-y PMC 바로가기 [Article Type] Article
Nutritional Modulation of Gut Microbiota Alleviates Severe Gastrointestinal Symptoms in a Patient with Post-Acute COVID-19 Syndrome장내 미생물총의 영양 조절은 급성 COVID-19 증후군 환자의 심각한 위장 증상을 완화합니다Case Reports Published on 2022-04-262022-09-11 Journal: mBio [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] 16S rRNA 16S rRNA gene acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alleviate alleviation alleviation of symptoms Anxiety Appetite arising ASV Bacteria baseline Care Case report change coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 pandemic COVID-19-related symptom COVID-19-related symptoms defined dosage Dysbiosis Expanded access fatty Fatty acid feasibility Gastrointestinal Gastrointestinal symptom gastrointestinal symptoms Gut gut microbiota Health IMPROVE in sight increase increase in IND indicate Infection insulin Intervention life long-hauler. long-lasting loss of appetite medication microbial microbiota modulating modulation nausea nutritional intervention palpitation Patient patient population patients with COVID-19 problem provided public health Quality of life reduce reduced rRNA SARS-CoV-2 SARS-CoV-2 detection sequence serum sight Significant significantly small intestine Symptom symptom severity syndrome target the patient variant [DOI] 10.1128/mbio.03801-21 PMC 바로가기 [Article Type] Case Reports
Can the SARS-CoV-2 Omicron Variant Confer Natural Immunity against COVID-19?SARS-CoV-2 오미크론 변이체가 COVID-19에 대한 자연 면역을 부여할 수 있습니까?Review Published on 2022-03-292022-09-11 Journal: Molecules [Category] SARS, 변종, [키워드] abatement acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Can causative agent cause claimed Community coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Evidence Hospitalization Human Hybrid immunity Immunity in sight increase in less Mutation natural natural immunity natural immunity. occur omicron Omicron variant Omicron variants pandemic predicted provide reduce Research resulting SARS-CoV-2 severe acute respiratory syndrome Coronavirus sight Spread subsequent surpassed Symptoms the disease the SARS-CoV-2 Transmissibility vaccination variant variants virus while [DOI] 10.3390/molecules27072221 PMC 바로가기 [Article Type] Review
COVID-19 antibody donation using immunoadsorption: Report of two cases면역흡착을 이용한 코로나19 항체 기증: 2건 보고Case Reports Published on 2021-10-012022-09-12 Journal: Transfusion and apheresis science : official journ [Category] MERS, SARS, 진단, [키워드] anti-SARS-CoV-2 antibodies antibody Antibody donation applied Autoimmune diseases benefit can be used Clinical efficacy coagulation factor component Concentration convalescent COVID-19 COVID-19 antibody COVID-19 convalescence COVID-19 pandemic Donor eight greater immunization Immunoadsorption Immunoglobulin in sight infected patient majority neutralization neutralized neutralizing antibody performed Peripheral blood plasma plasma unit promote report severe COVID-19 Side effects Standardization tangential flow filtration therapy transfused Treatment trials university Virus neutralization [DOI] 10.1016/j.transci.2021.103193 PMC 바로가기 [Article Type] Case Reports
One-Step, Wash-free, Nanoparticle Clustering-Based Magnetic Particle Spectroscopy Bioassay Method for Detection of SARS-CoV-2 Spike and Nucleocapsid Proteins in the Liquid Phase액상에서 SARS-CoV-2 스파이크 및 뉴클레오캡시드 단백질 검출을 위한 원스텝, 무세척, 나노입자 클러스터링 기반 자기 입자 분광법 생물검정 방법Article Published on 2021-09-222022-09-11 Journal: ACS applied materials & interfaces [Category] SARS, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 binding bioassay Biomarker Biomarkers cause changes in Clusters coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 detectable detection Detection limit diagnostic Diagnostic method disease disease diagnostics Disease surveillance ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Epidemic functional global pandemic group in sight intrinsically liquid magnetic nanoparticle Magnetic particle spectroscopy measure Medical resources MNP MONITOR MPS nanoparticle nucleocapsid nucleocapsid protein Nucleocapsid proteins pandemic Particle phase platform polyclonal antibodies polyclonal antibody qRT-PCR qualitative detection Quantitative quantitative reverse transcription-PCR Region response reverse transcription-PCR SARS-CoV-2 SARS-CoV-2 spike severe acute respiratory syndrome Coronavirus sight Spectroscopy spike Spike protein Surveillance the disease Traditional variety [DOI] 10.1021/acsami.1c14657 PMC 바로가기 [Article Type] Article
Reflections on 40 Years of AIDSPerspective Published on 2021-06-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, SARS, [키워드] acquired immune deficiency syndrome AIDS Antiretroviral therapy coronavirus disease COVID-19 defined Ebola Epidemics forty years Health Health security history HIV HIV testing HIV/AIDS Human immunodeficiency virus in sight infections Intervention lesson Other Pandemics Reflection Research respond SDGs Threats Treatment Year [DOI] 10.3201/eid2706.210284 PMC 바로가기 [Article Type] Perspective
Rethinking and strengthening the Global Health Diplomacy through triangulated nexus between policy makers, scientists and the community in light of COVID-19 global crisisPerspective Published on 2021-04-132022-10-31 Journal: Global Health Research and Policy [Category] COVID-19, MERS, [키워드] And science diplomacy approach Community COVID-19 COVID-19 pandemic death division Efficacy exacerbated global health Global health diplomacy Government Health Healthcare systems in sight lack measure mechanisms National pandemic Policy question Region Rethinking robust spreading Vaccine vaccine diplomacy virus Virus Disease while [DOI] 10.1186/s41256-021-00195-2 PMC 바로가기 [Article Type] Perspective
Surveillance Metrics of SARS-CoV-2 Transmission in Central Asia: Longitudinal Trend AnalysisOriginal Paper Published on 2021-02-032022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] addition Analysis applied approach Arellano-Bond estimator, generalized method of moments Armenia Asia average averaged Azerbaijan caused Central Asia COVID transmission acceleration Central Asia COVID-19 Central Asia COVID-19 surveillance system Central Asia COVID-19 transmission speed Central Asia econometrics Central Asia public health surveillance Central Asia SARS-CoV-2 Central Asia surveillance metrics country COVID-19 COVID-19 7-day lag COVID-19 pandemic COVID-19 transmission COVID-19 transmission deceleration COVID-19 transmission jerk Cyprus death driving dynamic panel data explain Faeroe Islands generalized method of moments Georgia Gibraltar global COVID-19 surveillance GMM growth Health highest impacted in sight increases in Infection infection rate infection rates Infectious disease Kazakhstan Kosovo Kyrgyzstan longitudinal Macedonia magnitude management Metrics monitoring objective pandemic per day persistence Policy positive prevention Public public health reported Result risk Russia SARS-CoV-2 SARS-CoV-2 surveillance SARS-CoV-2 transmission second wave Spread Study design Surveillance Tajikistan Turkey trajectory Transmission transmission rates trend trend analysis Turkey Turkmenistan Uzbekistan variable virus wave two [DOI] 10.2196/25799 PMC 바로가기 [Article Type] Original Paper
Multiple Sclerosis and SARS-CoV-2 Vaccination: Considerations for Immune-Depleting TherapiesReview Published on 2021-01-282022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome Alemtuzumab antibody CD20 depletion Cladribine coronavirus coronavirus disease COVID COVID-19 disease-modifying drugs hazard immune-depleting therapies immunological effect in sight Multiple multiple sclerosis overcome pandemic question raised recommendation SARS-CoV-2 sclerosis therapy Treatment vaccination [DOI] 10.3390/vaccines9020099 PMC 바로가기 [Article Type] Review