in vivo imaging – Communicable Diseases Research

[Correlation of the CTD structural domain of hepatitis B virus core protein with the encapsulation effect of indocyanine green]

Article

Published on 2022-03-252023-06-11
Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology
[Category] B형 간염,

[키워드] encapsulation efficiency hepatitis B virus core protein in vivo imaging indocyanine green polyarginine domain.
[DOI] 10.13345/j.cjb.210252 PMC 바로가기

Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression

K18-hACE2 마우스의 치명적인 신경 보급 및 SARS-CoV-2 향성은 hACE2 발현에 부분적으로만 의존합니다

Article

Published on 2022-03-052022-09-11
Journal: Viruses
[Category] SARS, 치료기술,

[키워드] ACE2 ACE2 protein ACE2-expressing cell ACE2-expressing cells Analysis angiotensin animal animal models AT1 axonal transport blood-brain barrier Brain bronchiolar Cell Cohort comparative pathology COVID-19 Critical cytokeratin cytokeratin 18 promoter days post-infection death Dependent detectable dose ENhance epidemiological data euthanasia evaluated Evidence expressing expression hACE2 Human human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 hypothermia immunohistochemistry In situ hybridization in vivo in vivo imaging independent independent of inoculated intranasal K18-hACE2 Lineage Mild-to-moderate neuroepithelium Neuron neurons occur olfactory olfactory bulb olfactory neuroepithelium overexpression pathologic PFUs Pneumocytes Pneumonia portal question resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis spatiotemporal subsequent transgenic mice translational translational animal model Transmission transmission electron microscopy Transport tropism vasculature viral pathogenesis Viral pathogenesis. Viremia Virological
[DOI] 10.3390/v14030535 PMC 바로가기 [Article Type] Article

Nonhuman Primates in Translational Research

Review

Published on 2022-02-152023-07-08
Journal: Annual review of animal biosciences
[Category] COVID19(2023년),

[키워드] developmental disorders Gene therapy immune system in vivo imaging Infectious diseases preclinical models.
[DOI] 10.1146/annurev-animal-021419-083813 PMC 바로가기 [Article Type] Review

Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses

리포터 발현 바이러스를 이용한 생체 내 SARS-CoV-2 감염 역학 분석

423

Published on 2021-10-122022-09-10
Journal: Proceedings of the National Academy of Sciences of
[Category] MERS, SARS, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin angiotensin converting enzyme antibody causative agent coronavirus COVID-19 COVID-19 pandemic CoVs cultured cell deleted deleting dissemination dynamic effective enzyme exhibited expressed expressing expression level fluorescent followed by Frame Genes hACE2 high stability identify in vitro in vivo in vivo imaging Infection K18 locus lung MONITOR neutralize noninvasive nucleocapsid Open reading frame ORF Pathogenesis pathogenicity Protein proteolytic cleavage public health replaced REPLACED BY Replication reporter reporter expression reporter gene reporter genes reporter viruses respiratory retained SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Significance the SARS-CoV-2 the viral nucleocapsid therapeutic intervention therapeutic interventions threat transgenic mice Treatment upstream Venus Viral viral infection viral replication virus viruses whole organism wild-type
[DOI] 10.1073/pnas.2111593118 PMC 바로가기 [Article Type] 423

Predictive Markers of Immunogenicity and Efficacy for Human Vaccines

Review

Published on 2021-06-012022-10-28
Journal: Vaccines
[Category] COVID-19,

[키워드] acute respiratory syndrome adopted animal model applied approach coronavirus Data analysis develop Efficacy effort help high-throughput technologies Human human populations humans identifying immune immune signature Immunity immunogenicity in silico in vivo imaging increasingly machine learning malaria marker methodology Pandemics Pathogens preclinical models preclinical study Predictive predictive biomarkers Predictive model probe protective responses Research responses SARS-CoV-2 Systems biology systems immunology translational Tuberculosis unsupervised analyses vaccination Vaccination strategies Vaccine vaccine candidate vaccine signatures Vaccines Zika virus
[DOI] 10.3390/vaccines9060579 PMC 바로가기 [Article Type] Review

Evaluation of monkeypox virus infection of black-tailed prairie dogs (Cynomys ludovicianus) using in vivo bioluminescent imaging

Article

Published on 2014-07-012023-06-09
Journal: Journal of wildlife diseases
[Category] Fulltext, 원숭이두창,

[키워드] bioluminescence black-tailed prairie dog Histopathology in vivo imaging Monkeypox virus orthopoxvirus poxvirus real-time PCR.
[DOI] 10.7589/2013-07-171 PMC 바로가기