individual patient data

[키워드] acute respiratory distress acute respiratory syndrome added analyzed anti-IL-6 anti-interleukin-6 receptor antibody average baseline baseline characteristics C-reactive protein (CRP Case report cause changes in Characteristics clinical Clinical outcome clinical outcomes Comorbidity coronavirus coronavirus disease COVID-19 COVID-19 patient CRP level current cytokine release storm Cytokine storm decrease demographics elevated Endpoint Evidence Fisher hospital hyperinflammatory state hypertension IL-6 IL-6 level IL-6 pathway in-hospital complications in-hospital mortality inclusion criteria individual level individual patient data inflammatory markers inhibition interleukin-6 interquartile range knowledge Laboratory male median nonsurvivor not significantly different observational study occurred outcome over pathway Patient patient data patients performed primary endpoint Primary outcome randomized control trial recent receptor reported SARS-CoV-2 secondary severe COVID-19 significantly significantly higher Standard deviation surviving patients survivor syndrome systematic review the primary endpoint therapy Tocilizumab treated Treatment worsened disease
[DOI] 10.1002/jmv.26038 PMC 바로가기 [Article Type] Article