Thymus in Cardiometabolic Impairments and Atherosclerosis: Not a Silent Player?Review Published on 2024-06-252024-09-05 Journal: Biomedicines [Category] update2024, [키워드] atherogenesis atherosclerotic plaque inflammaging T lymphocytes thymus adipose tissue thymus atrophy [DOI] 10.3390/biomedicines12071408 PMC 바로가기 [Article Type] Review
Immune cell phenotypes and mortality in the Framingham Heart StudyResearch Published on 2024-06-122024-09-05 Journal: Immunity & Ageing : I & A [Category] update2024, [키워드] aging all-cause mortality Cardiovascular mortality Immune cell phenotype immune system immunosenescence inflammaging Non-cardiovascular mortality T cells [DOI] 10.1186/s12979-024-00431-6 PMC 바로가기 [Article Type] Research
Increased levels of GM-CSF and CXCL10 and low CD8 + memory stem T Cell count are markers of immunosenescence and severe COVID-19 in older peopleResearch Published on 2024-05-072024-09-05 Journal: Immunity & Ageing : I & A [Category] update2024, [키워드] CD8-positive T-lymphocytes COVID-19 CXCL10 Geriatrics GMCSF Immune-ageing immunosenescence infections inflammaging senescence-associated secretory phenotype TSCM [DOI] 10.1186/s12979-024-00430-7 PMC 바로가기 [Article Type] Research
Emerging Vistas for the Nutraceutical Withania somnifera in InflammagingReview Published on 2024-05-072024-09-05 Journal: Pharmaceuticals [Category] update2024, [키워드] aging COVID-19 DNA damage healthy aging immunomodulation inflammaging Inflammation Microbiome oxidative stress Withania somnifera [DOI] 10.3390/ph17050597 PMC 바로가기 [Article Type] Review
The Impact of Immune System Aging on Infectious DiseasesReview Published on 2024-04-112024-09-05 Journal: Microorganisms [Category] update2024, [키워드] aging immunosenescence Infectious disease inflammaging vaccination [DOI] 10.3390/microorganisms12040775 PMC 바로가기 [Article Type] Review
Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapyReview Article Published on 2023-12-182024-09-05 Journal: Redox Report : Communications in Free Radical Rese [Category] update2024, [키워드] Ageing antioxidants frailty Geriatrics inflammaging Multimorbidity oxidative stress polypharmacy [DOI] 10.1080/13510002.2023.2289740 PMC 바로가기 [Article Type] Review Article
On frailty and accelerated aging during SARS-Cov-2: senescencearticle Published on 2023-03-202024-09-05 Journal: Aging Clinical and Experimental Research [Category] update2024, [키워드] aging biological age coronavirus COVID-19 frailty inflammaging senescence [DOI] 10.1007/s40520-023-02364-4 PMC 바로가기 [Article Type] article
Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing homearticle Published on 2023-03-062024-09-05 Journal: Immunity & Ageing : I & A [Category] update2024, [키워드] antibody waning BNT162b2 vaccine Immunesenescence inflammaging Magnitude and persistence of humoral response nursing home RTL Sj/β-TRECs ratio Thymic-function Thymosin-α1 [DOI] 10.1186/s12979-023-00334-y PMC 바로가기 [Article Type] article
Repurposing SGLT-2 Inhibitors to Target Aging: Available Evidence and Molecular MechanismsArticle Published on 2022-10-142022-11-15 Journal: International Journal of Molecular Sciences [Category] 신약개발, 진단, [키워드] accompanied activity addition aging all-cause mortality animal model animal models available data benefit Biomarker blunt caloric restriction calories cardiovascular diseases Cardiovascular outcomes cellular senescence clinical study clinical trials Compound COVID-19 decrease diabetes driver drug drugs employment Evidence Fatty acid feature Glucose heart failure humans IL-6 independent inflammaging Inflammasome inhibitor inhibitors intrinsic Kidney disease low-grade inflammation Meta-analysis modulating modulation molecular Mortality nutrient-sensing pathways observational studies outcomes pathway Patient promote provided repurposing selected senescence sodium-glucose cotransporter 2 inhibitors. substrates suggested Support systemic effects systemic level target Urine [DOI] 10.3390/ijms232012325 PMC 바로가기
Inflammaging at the Time of COVID-19Review article Published on 2022-08-012022-10-05 Journal: Clinics in Geriatric Medicine [Category] SARS, 바이오마커, [키워드] COVID-19 Cytokines diet immunosenescence inflammaging Inflammation Long COVID Older adults physical activity SARS-CoV-2 time [DOI] 10.1016/j.cger.2022.03.003 [Article Type] Review article