Questionnaire survey of risk factors for recurrence of ocular inflammation in patients with uveitis after SARS-CoV-2 infectionarticle Published on 2024-01-302024-09-05 Journal: Frontiers in Cellular and Infection Microbiology [Category] update2024, [키워드] inflammatory activity Relapse SARS-COV-2 infection systemic immunosuppressive therapy Uveitis [DOI] 10.3389/fcimb.2023.1291991 PMC 바로가기 [Article Type] article
C-reactive protein cut-off for early tocilizumab and dexamethasone prescription in hospitalized patients with COVID-19COVID-19로 입원한 환자의 초기 토실리주맙 및 덱사메타손 처방에 대한 C 반응성 단백질 차단Article Published on 2022-03-282022-09-12 Journal: Scientific Reports [Category] SARS, 바이오마커, 임상, 진단, 치료법, 치료제, [키워드] 30-day mortality rate Admission age Analysis Anti-inflammatory therapy C-reactive protein C-reactive protein (CRP CRP cut-off defined Dexamethasone evaluated help hospital hospitalized patient independent predictor Infection inflammatory activity intensive care Interaction IQR males median Mortality Multivariate analysis outcome Patient performed Primary outcome receiving reduction in reduction in mortality SARS-CoV-2 stratified Tocilizumab variable viral replication with COVID-19 [DOI] 10.1038/s41598-022-08882-x PMC 바로가기 [Article Type] Article
Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infectionSARS-CoV-2 감염에 대한 자가항체 반응의 역설적인 성별 특정 패턴Research Published on 2021-12-302022-09-10 Journal: Journal of Translational Medicine [Category] SARS, 진단, 치료법, [키워드] AABs absence Activation acute response age analyses antibody Antigen antigens assigned asymptomatic infection autoantibody autoantigen Autoantigen selectivity Autoimmune Autoimmune disease Autoimmune diseases autoreactivity blood draw breadth classic clinical disease Clustering Cohort collected COVID-19 COVID-19 illness demographic data effective intervention effective interventions Evidence evidence of exhibit extreme greater healthy control homology Immune-mediated inflammatory activity lead men men and women modulating molecular multivariable analyses nucleocapsid protein number of symptom participant presence or absence Prevalence reactivity reported symptom reported symptoms Result SARS-CoV-2 SARS-COV-2 infection serological severe COVID-19 illness Sex difference sex differences socio-demographic supplementary material susceptibility Symptom symptomatic infection Symptoms trajectory triggered within 6 months women [DOI] 10.1186/s12967-021-03184-8 PMC 바로가기 [Article Type] Research
Detection of SARS-CoV-2 virus using an alternative molecular method and evaluation of biochemical, hematological, inflammatory, and oxidative stress in healthcare professionals대체 분자 방법을 사용한 SARS-CoV-2 바이러스 검출 및 의료 전문가의 생화학적, 혈액학적, 염증성 및 산화적 스트레스 평가Article Published on 2021-09-012022-09-11 Journal: Microbial pathogenesis [Category] SARS, 치료기술, [키워드] Alanine alanine aminotransferase ALT aspartate Aspartate aminotransferase AST biochemical both groups Brazil C-reactive protein caused changes in China cholesterol city condition coronavirus coronavirus disease Coronavirus disease 2019 corpuscular cortisol damage detection detrimental diagnosed elevated eosinophil eosinophils evaluated group HDL Health Health Organization Health professionals Healthcare professional hematocrit hematological hemoglobin immunochromatographic test individual Inflammation Inflammatory inflammatory activity inflammatory changes International lactic lactic dehydrogenase LDH leukocytes Lymphocytes marker mean corpuscular volume mental health molecular Monocytes mucoprotein Neutrophils new strain new strain of coronavirus occurred outbreak oxidative damage oxidative stress Participants percentage percentages physical plasma Platelet Platelets professional professionals public health emergency qRT-PCR reduced RT-LAMP RT-PCR Saliva saliva samples salivary SARS-CoV-2 SARS-CoV-2 virus significant increase significantly Stress stressful situation study population the SARS-CoV-2 virus Triglyceride triglycerides uninfected uric acid Volume were infected WHO World Health Organization Wuhan [DOI] 10.1016/j.micpath.2021.104975 PMC 바로가기 [Article Type] Article
Cross-sectional analysis of follow-up chest MRI and chest CT scans in patients previously affected by COVID-19COVID-19에 의해 이전에 영향을받은 환자의 후속 흉부 MRI 및 흉부 CT 스캔의 단면 분석Chest Radiology Published on 2021-07-122022-09-01 Journal: La Radiologia Medica [Category] MERS, SARS, 진단, [키워드] abnormality Accuracy affected agreement Analysis Biomarker bronchiolar calculated change Chest Chest computerized tomography Chest CT chest CT scan Chest magnetic resonance imaging chest MRI Computed tomography consolidation coronavirus disease Coronavirus disease 2019 COVID-19 CT scans diagnostic Diagnostic accuracy evaluate evaluated fibrosis Follow-up GGO GGOs Ground-glass opacities ground-glass opacity Inflammation inflammatory activity interlobular septal thickening magnetic resonance imaging material measure MRI Patient Pneumonia positive predominant Result sensitivity specificity vessel [DOI] 10.1007/s11547-021-01390-4 PMC 바로가기 [Article Type] Chest Radiology
Effect of Convalescent Plasma in Critically Ill Patients With COVID-19: An Observational StudyMedicine Published on 2021-01-282022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 28-day mortality acute respiratory distress syndrome age Analysis baseline Biomarker Brazil clinical Clinical improvement conducted convalescent plasma coronavirus coronavirus disease COVID-19 COVID-19 patient Critically ill patient disease Effect Efficacy Final Follow-up hazard ratio IgG titer Ill increase in inflammatory activity IQR Kaplan–Meier laboratory-confirmed life-threatening Lymphocyte count mechanically ventilated occurred outcome Patient patients performed plasma prospective observational study reduced Registered registry Respiratory failure Rio de Janeiro secondary single-center Standard of care Study protocol survival therapeutic option viral loads with COVID-19 [DOI] 10.3389/fmed.2021.630982 PMC 바로가기 [Article Type] Medicine
Age is not the only risk factor in COVID-19: the role of comorbidities and of long staying in residential care homesResearch Article Published on 2021-01-152022-10-27 Journal: BMC Geriatrics [Category] COVID-19, [키워드] Admission age analyzed association Blood Bonferroni correction Care categorical variable caused clinical outcomes Comorbidities Comorbidity computer tomography COVID 19 develop diagnosis of COVID-19 disease elderly Elderly patient examined Factors FiO2 Fisher’s exact test Hospital stay increased mortality index inflammatory activity information inspired oxygen fraction Kaplan-Meier method Laboratory tests Logistic regression LOS manifestation Mann-Whitney U test mortality rate multiple comorbidities multiple group multivariate Occurrence outbreak outcome oxygen P/F PaO2 Patient patients patients older performed PSI radiological finding RANK Residential care homes Result Retrospective study risk factor risk stratification Rome SARS-CoV-2 Severity of disease Sex single-center survival susceptible Symptom Test the disease two group university variables viral shedding Wilcoxon signed-rank test [DOI] 10.1186/s12877-021-02013-3 PMC 바로가기 [Article Type] Research Article
Age is not the only risk factor in COVID-19: the role of comorbidities and of long staying in residential care homesResearch Article Published on 2021-01-152022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID-19, MERS, [키워드] Admission age analyzed association Blood Bonferroni correction Care categorical variable caused clinical outcomes Comorbidities Comorbidity computer tomography COVID 19 develop diagnosis of COVID-19 disease elderly Elderly patient examined Factors FiO2 Fisher’s exact test Hospital stay increased mortality index inflammatory activity information inspired oxygen fraction Kaplan-Meier method Laboratory tests Logistic regression LOS manifestation Mann-Whitney U test mortality rate multiple comorbidities multiple group multivariate Occurrence outbreak outcome oxygen P/F PaO2 Patient patients patients older performed PSI radiological finding RANK Residential care homes Result Retrospective study risk factor risk stratification Rome SARS-CoV-2 Severity of disease Sex single-center survival susceptible Symptom Test the disease two group university variables viral shedding Wilcoxon signed-rank test [DOI] 10.1186/s12877-021-02013-3 PMC 바로가기 [Article Type] Research Article
Previous and First Detected Cardiovascular Diseases in Patients with New Coronavirus Pneumonia: Possible Mechanisms and Place in a Unified Prognostic Model신종 코로나바이러스 폐렴 환자에서 이전 및 최초로 발견된 심혈관 질환: 통합 예후 모델에서 가능한 기전 및 위치Article Published on 2021-01-012022-09-12 Journal: International archives of allergy and immunology [Category] 진단, [키워드] addition age AHA Anti-heart antibodies antibody average C-reactive protein cardiac cardiovascular cardiovascular disease cause coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus pneumonia correlation correlation coefficient COVID-19 D-dimer death diabetes disease disorders evaluate Frequency heart failure Heart injury hospital immune mechanism incidence include indicate Inflammatory inflammatory activity Injury lethality leukocyte male Manifestations mechanisms Model myocardial injury myocarditis New Oxygen therapy pathology Patient patients with COVID-19 Pneumonia predictive power Prognosis Prognostic factors prognostic model prothrombotic Respiratory failure sensitivity Significant specificity Symptom Symptoms Volume was increased were used with COVID-19 [DOI] 10.1159/000515253 PMC 바로가기 [Article Type] Article
Taming the Autophagy as a Strategy for Treating COVID-19COVID-19 치료를 위한 전략으로 자가포식 길들이기Review Published on 2020-12-132022-09-11 Journal: Cells [Category] SARS, 치료제, [키워드] activate activating addition Analysis Antiviral autophagy chemokine clinical decision Complication COVID-19 cytokine Cytokine storm Evidence Factor guide highlight IFN-I IFN-I response IFN-III Inflammation inflammatory activity inhibit inhibiting interferon mechanism obesity Pathogenesis pathogenesis of COVID-19 physiological Previous studies question Research reveal robust SARS-CoV-2 SARS-COV-2 infection severe COVID-19 Strategy Therapeutic approach Topic treating Treatment treatment for COVID-19 triggered type I [DOI] 10.3390/cells9122679 PMC 바로가기 [Article Type] Review