Comparative Upper Respiratory Tract Transcriptomic Profiling Reveals a Potential Role of Early Activation of Interferon Pathway in Severe COVID-19Article Published on 2022-10-012022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제, [키워드] Acute respiratory infection Comparative Coronavirus disease 2019 COVID-19 COVID-19 negative COVID-19 patient COVID-19 patients death driving evaluated Genes Host transcriptional response host-pathogen interactions IFN-I IFN-I response Inflammation initial symptom interferon involved ISG ISGs lung mechanism Mild OAS Potential Profiling progression respiratory Respiratory failure RNA-Seq RNA-sequencing role SARS-CoV-2 severe COVID-19 patient severe COVID-19 patients severe symptom stimulated symptomatic patient the disease tract type I interferon upper upper respiratory tract upregulated viral infection Viral load [DOI] 10.3390/v14102182 PMC 바로가기
Saliva for molecular detection of SARS-CoV-2 in pre-school and school-age childrenArticle Published on 2022-10-012022-11-15 Journal: Environmental microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Adults age asymptomatic subjects children collected comparable contrary coronavirus disease COVID-19 detection rate Diagnosis early stage independent Infection initial initial symptom invasive less management molecular nasopharyngeal NPs Numerous Patient performance RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 detection sensitivity serological seronegative significantly significantly lower Symptoms [DOI] 10.1111/1462-2920.16151 PMC 바로가기
When to test for COVID-19 using real-time reverse transcriptase polymerase chain reaction: a systematic reviewReview article Published on 2022-10-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 치료기술, [키워드] addition affected analyzed article Case series cohorts conducted coronavirus cough country COVID-19 COVID-19 testing Cross-sectional studies database described Dyspnea evaluate Fever first positive health units Infection initial symptom median age objective participant Patient patients polymerase chain positive positive test result real-time reverse transcriptase Real-time reverse transcriptase polymerase chain reaction reported Result retrospective cohorts RT-PCR RT-PCR test RT-PCR testing SARS-CoV-2 Symptom symptom onset systematic review the MEDLINE [DOI] 10.1016/j.ijid.2022.06.037 [Article Type] Review article
Developing a Loop-Mediated Isothermal Amplification Assay for the Rapid Detection of Seven Respiratory Viruses including SARS-CoV-2Article Published on 2022-09-052022-11-15 Journal: Medicina [Category] SARS, 신종인플루엔자, 치료기술, 치료제, [키워드] Accuracy acute respiratory syndrome Adenovirus amplification caused coronavirus coronavirus disease COVID-19 cross-reactivity detection develop Developing diagnosis of COVID-19 evaluate facilitate Final H1N1 H3N2 heat-inactivated include Infection Influenza initial symptom isothermal isothermal amplification material median multiplex Nasopharyngeal swab objective overlap pandemic Patient patients PCR performed point-of-care polymerase chain Quantitative quantitative PCR Rapid reagent respiratory respiratory infection respiratory syncytial virus respiratory virus respiratory viruses RSV RT-PCR RT-qLAMP RT-qPCR RT-qPCR assay SARS-CoV-2 Sensitivity and specificity Seven specimen strain Symptom target specificity time-consuming Treatment Volume was performed were used [DOI] 10.3390/medicina58091224 PMC 바로가기
Public Health Response to a Case of Paralytic Poliomyelitis in an Unvaccinated Person and Detection of Poliovirus in Wastewater – New York, June-August 2022백신 접종을 하지 않은 사람의 마비성 소아마비 발병 사례에 대한 공중 보건의 대응 및 폐수 내 소아마비 바이러스 검출 - 2022년 6월-8월 뉴욕Case Reports Published on 2022-08-192022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] SARS, 치료기술, 폴리오, [키워드] AFM America Americas caused CDC collected community transmission Coverage Department detected in stool detection Fever gastrointestinal symptoms Health Organization Hospitalized initial symptom limb limb weakness neck stiffness New York occurred Occurrence orange Paralytic paralytic polio Patient Person polio Poliovirus Prevent Public Region residence response Rockland SARS-CoV-2 specimen state Stool symptom onset the patient the United State United States vaccination wastewater weakness World Health Organization [DOI] 10.15585/mmwr.mm7133e2 PMC 바로가기 [Article Type] Case Reports
Rule Extraction for Screening of COVID-19 Disease Using Granular Computing Approach세분화된 컴퓨팅 접근 방식을 사용한 COVID-19 질병 스크리닝을 위한 규칙 추출Article Published on 2022-06-222022-09-11 Journal: Computational and Mathematical Methods in Medicine [Category] 치료기술, [키워드] access to treatment affected appear approach Care collected computing congestion COVID-19 COVID-19 disease detect diagnosing disease early diagnosis Experimental result experimental results extraction feature granular health center initial symptom initial symptoms Patient problem Quality of service reduce reported rule Screening service Statistics Symptom Symptoms the epidemic training dataset Treatment variety virus [DOI] 10.1155/2022/8729749 PMC 바로가기 [Article Type] Article
Ivermectin for preventing and treating COVID-19COVID-19 예방 및 치료를 위한 이버멕틴Review Published on 2022-06-212022-09-11 Journal: The Cochrane database of systematic reviews [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Admission adverse event adverse events all-cause mortality antiparasitic Antiviral approach ARMS Asymptomatic certainty certainty of evidence citation classification Clinical improvement clinical trial Cochrane COVID-19 Study Register coronavirus coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 symptoms COVID-19 treatment Data collection database death discharged disease disease severity double-blind duration of symptom early stage early stages Efficacy Efficacy and safety eligible Evidence excluded for inclusion GRADE hospital identify in vitro include increase index Infection infection with SARS-CoV-2 inhibit inhibitory effect initial symptom Inpatient Inpatients Intervention Invasive mechanical ventilation investigated Ivermectin life mean difference Mental Meta-analysis Mild Moderate COVID-19 moderate-to-severe COVID-19 molecular hypothesis Mortality no effect non-randomized ongoing trial ongoing trials Open-label outcome Outpatient outpatients participant Participants people with COVID-19 physical Placebo placebo-controlled Postexposure Prophylaxis Prevent Quality of life question Randomized controlled trial Randomized controlled trials RCT RCTs receiving reduce Registered Replication Reporting request Research resolved risk Risk of bias risk ratio RoB 2 SARS-CoV-2 SARS-COV-2 infection Science Citation Index searched Selection Serious Adverse Event Serious Adverse Events Seven severe acute respiratory syndrome Coronavirus Standard of care treat treated treating COVID-19 Treatment Trial trials viral clearance virus Web of Science WHO WHO guideline worsening [DOI] 10.1002/14651858.CD015017.pub3 PMC 바로가기 [Article Type] Review
Tonic non-colonic convulsions-status epilepticus- as the presenting complaint of COVID-19Case report Published on 2022-06-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 진단, [키워드] Anosmia Brain Chest clonic Computed tomography coronavirus COVID-19 COVID-19 infection COVID19 diagnostic workup Dizziness epilepsy etiologies Headaches initial symptom literature review Loss of consciousness male neurological manifestation Neurological symptom Neurological symptoms presenting respiratory virus Seizure severe COVID-19 stroke Symptom Tonic tonic convulsion [DOI] 10.1016/j.amsu.2022.103744 [Article Type] Case report
Timely treatment and higher compliance to traditional Chinese medicine: New influencing factors for reducing severe COVID-19 based on retrospective cohorts in 2020 and 2021Research article Published on 2022-04-012022-10-05 Journal: Pharmacological research [Category] COVID19(2023년), SARS, 변종, 치료법, [키워드] addition adhere age Antibiotics antiviral medicine association calculated changed characterized Chinese cohort study cohorts collected Compliance Concomitant medication conditions conducted control limit COVID-19 patient COVID-19 patients diagnosed Diagnosis disease E-value effective Effectiveness enrolled Epidemic Factor Final hospital Hospitalization Hospitalized incidence independent risk factor initial symptom initial symptoms LCL less measure Mild mild COVID-19 Moderate COVID-19 multivariate logistic regression New objective outcome participant Patient predict Prognosis progressed proportion public health reduced reducing Result retrospective cohort retrospective cohort study sensitivity analysis Severe case severe cases severe COVID-19 Severity of disease Sex TCM The proportion to severe status Traditional Chinese medicine treat Treatment were used Wuhan [DOI] 10.1016/j.phrs.2022.106174 [Article Type] Research article
Characteristics and impact of Long Covid: Findings from an online surveyResearch Article Published on 2022-03-082022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] age agglomerative hierarchical clustering analysed Analysis antibody baseline Belonging Cardiopulmonary carried Characteristics Chest Cluster Clusters cognitive collected comparison Confirmed COVID-19 infection COVID-19 COVID-19 illness described duration of illness dysfunction enrolled exhibiting exploratory female finding functional headache Health heterogeneity highlight hospitalised identify Infection initial initial symptom interquartile range IQR Long majority median MOST multisystem symptoms palpitation participant PCR predictor predominant Prevalence prevalent Prognosis public health relapsing reported Research Result SARS-COV-2 infection Shortness of breath Sleep disturbance specific symptom Standard deviation Stress Symptom Symptoms triggered was used [DOI] 10.1371/journal.pone.0264331 PMC 바로가기 [Article Type] Research Article