Functional Divergence of the Paralog Salmonella Effector Proteins SopD and SopD2 and Their Contributions to Infection파라로그 살모넬라 효과 단백질 SopD와 SopD2의 기능적 분화 및 감염에 대한 기여Article Published on 2024-04-102024-08-21 Journal: International Journal of Molecular Sciences [Category] 살모넬라증, [키워드] Bacterial pathogenesis effector protein host–pathogen interactions intracellular pathogen intracellular trafficking Rab GTPase Salmonella enterica
Mycobacterium leprae’s Infective Capacity Is Associated with Activation of Genes Involved in PGL-I Biosynthesis in a Schwann Cells Infection Model마이코박테리움 레프라의 감염 능력은 슈반 세포 감염 모델에서 PGL-I 생합성에 관여하는 유전자의 활성화와 관련이 있다.Article Published on 2023-05-132024-08-24 Journal: International Journal of Molecular Sciences [Category] 한센병, [키워드] Infection intracellular pathogen leprosy recurrence Mycobacterium leprae (M. leprae) phenolic glycolipid-I (PGL-I). Schwann cells (SCs)
PathogenTrack and Yeskit: tools for identifying intracellular pathogens from single-cell RNA-sequencing datasets as illustrated by application to COVID-19PathogenTrack 및 Yeskit: COVID-19에 적용하여 설명된 단일 세포 RNA 시퀀싱 데이터 세트에서 세포내 병원체를 식별하기 위한 도구Article Published on 2022-04-012022-09-11 Journal: Frontiers of medicine [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] addition Analysis Antigen Bacteria bacterium BALF Bronchoalveolar lavage fluid cancers cell type cellular cellular distribution Co-infection COVID-19 COVID-19 patient COVID-19 patients database dataset dysfunction epithelial cell epithelial cells feature fungi Github Haemophilus host cell host cells identify immune response in some increased expression induce Infectious disease interferon pathway intracellular pathogen introduced Macrophage macrophages microbe neutrophil other disease other diseases pathogen Pathogens pathway presenting R package raw data robustness SARS-CoV-2 SARS-CoV-2 virus scRNA-seq scRNA-seq data scRNA-seq datasets Severe case single-cell level Single-cell RNA-sequencing SRA Still Taking tested the SARS-CoV-2 virus transcriptomic type I interferon type I interferon pathway viruses [DOI] 10.1007/s11684-021-0915-9 PMC 바로가기 [Article Type] Article
Shigella flexneri Diguanylate Cyclases Regulate Virulence시겔라 플렉스네리 디구아닐레이트 사이클라제는 병원성을 조절한다.Article Published on 2021-11-052024-08-22 Journal: Retinal cases & brief reports [Category] 세균성이질, [키워드] biofilm c-di-GMP cell-cell spread diguanylate cyclase intracellular pathogen Invasion Shigella
COVID-19 Pandemic and Vaccines Update on Challenges and ResolutionsCOVID-19 팬데믹 및 백신 관련 과제 및 해결 방법 업데이트Review Published on 2021-09-102022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 변종, [키워드] ACE-2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 all age group all age groups Alpha Antibody-dependent enhancement approach approval approved attenuated vaccine Attenuated Virus B.1.1.7 B.1.351 B.1.429 B.1.525 B.1.617 B.1.617.2 BCG being Beta booster dose candidate vaccine caused CD8 challenge China city clinical development clinical trial combating Compliance contrary Coronaviridae family coronavirus coronavirus disease Coronavirus-2 COVID-19 CTL Delta disease severity Effectiveness Efficacy elicit Emergency use Epsilon Eta Gamma herd immunity host cells immune activation immune response immune responses Immunity inactivated Inactivated Vaccines inhibit intracellular pathogen Live attenuated vaccine MOST Multiple multiple antigens multivariant vaccines Mutation mutations Neutralizing antibodies neutralizing antibody nucleic acids pandemic pathogen Phase III clinical trials platform potential limitations Prophylactic Replication Resolution RNA virus SARS CoV-2 variant SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Spike protein subunit vaccines T cell the Coronaviridae Vaccine vaccine candidate Vaccine hesitancy Vaccines variant variants Viral Viral antigen viral antigens viral entry viral spike protein viral vectors virus viruses WHO Wuhan [DOI] 10.3389/fcimb.2021.690621 PMC 바로가기 [Article Type] Review
Mycobacterium leprae’s evolution and environmental adaptationarticle Published on 2019-09-302024-09-01 Journal: Family process [Category] 한센병, [키워드] Genome intracellular pathogen leprosy Mycobacterium leprae pseudogene reductive evolution [Article Type] article
Salmonella Typhimurium Infection of Human Monocyte-Derived Macrophagesarticle Published on 2018-08-312024-09-01 Journal: Curr Protoc Microbiol [Category] 살모넬라증, [키워드] Bacteria Infection intracellular pathogen macrophages monocyte-derived macrophage Salmonella [Article Type] article
Influential Parameters for the Analysis of Intracellular Parasite Metabolomics세포내 기생충 대사체 분석을 위한 영향력 있는 매개변수Research Article Published on 2018-04-182024-08-11 Journal: mSphere [Category] 말라리아, [키워드] apicomplexan parasites intracellular pathogen metabolomics Plasmodium falciparum [DOI] 10.1128/mSphere.00097-18 PMC 바로가기 [Article Type] Research Article
Controlled branched-chain amino acids auxotrophy in Listeria monocytogenes allows isoleucine to serve as a host signal and virulence effectorListeria monocytogenes의 조절된 분지쇄 아미노산 영양요구성은 이소류신이 숙주 신호 및 독성 효과기 역할을 할 수 있도록 합니다.Research Article Published on 2018-03-122022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activate adaptation amino acids Bacteria Bacterial pathogens BCAA BCAA biosynthesis BCAA biosynthesis genes branched-chain amino acid branched-chain amino acids CodY conditions Control Controlled deficiency dependent on downstream gene downstream genes Evidence expression function Gene regulation highlight Host Infection intracellular pathogen isoleucine L . monocytogene Listeria Listeria monocytogene Listeria monocytogenes mammalian cell mechanism metabolic pathway metabolic pathways metabolism metabolites occur pathogen pathogenic Pathogens regulate Regulation represse respond restrict Rli60 saprophyte switching transcribed transition Trigger triggers upregulated upstream virulence virulence gene virulence genes virulent while [DOI] 10.1371/journal.pgen.1007283 PMC 바로가기 [Article Type] Research Article
Small Molecule Restores Itaconate Sensitivity in Salmonella enterica: A Potential New Approach to Treating Bacterial Infections소분자가 살모넬라 엔테리카에서 이타코네이트 민감성을 회복시킴: 박테리아 감염 치료를 위한 잠재적인 새로운 접근법Article Published on 2016-08-172024-08-21 Journal: ChemBioChem [Category] 살모넬라증, [키워드] Antibiotics intracellular pathogen itaconate degradation Medicinal chemistry pantothenate.