Comparative bioavailability study following a single dose intravenous and buccal administration of remdesivir in rabbits토끼에서 렘데시비르의 단일 용량 정맥내 및 협측 투여 후 비교 생체이용률 연구Article Published on 2022-05-252022-09-11 Journal: International journal of pharmaceutics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] administration Antiviral Beta-cyclodextrin Bioavailability blood collection Buccal Buccal administration can be used Comparative early stage effective ether FDA-approved drug Formulation GS-441524 hospitalized patient hospitalized patients IMPROVE Infection intravenous Intravenous administration intravenous route intravenously metabolite Pharmacokinetic study pharmacokinetics plasma provided Rabbits Remdesivir required SARS-COV-2 infection significantly lower single dose treated Treatment [DOI] 10.1016/j.ijpharm.2022.121739 PMC 바로가기 [Article Type] Article
Rationale for the clinical use of adipose-derived mesenchymal stem cells for COVID-19 patients코로나19 환자를 위한 지방유래 중간엽줄기세포의 임상적 사용 근거Review Published on 2020-05-182022-09-10 Journal: Journal of Translational Medicine [Category] MERS, SARS, 비임상, [키워드] acute respiratory distress acute respiratory distress syndrome administration alveolar fluid clearance animal model animal models antimicrobial ARDS ASC benefit breath capital city Cell China Clinical studies clinical study Clinical use Comorbidity coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 outbreak COVID-19 patient Critical demonstrated distress edema effective Ex vivo Fever global pandemic globe greater Health Organization healthcare high mortality rate hospital resources human clinical trials human lung hypoxia illness immune response immune responses immunomodulatory activities in some in vivo Inflammation inhibit intravenous Intravenous administration intravenous route lead Local lung lung damage Lungs majority Mesenchymal stem cells molecules morbidity morbidity and mortality MSC MSCs multi-organ failure Multiple Novel coronavirus older patients Pain Patient patient mortality per day Pneumonia pulmonary disease Pulmonary edema Pulmonary function rationale reduce reduced respiratory respiratory distress respiratory symptoms risk Safe SARS-CoV-2 SARS-COV-2 infection severe disease Severe respiratory distress stem cell stem cells syndrome therapeutic option therapy Travel Treatment treatment of COVID-19 Viral viral outbreak viral respiratory with COVID-19 World Health Organization Wuhan [DOI] 10.1186/s12967-020-02380-2 PMC 바로가기 [Article Type] Review
Safety and efficacy of phage therapy via the intravenous route정맥 경로를 통한 파지 요법의 안전성과 효능journal-article Published on 2016-02-012024-08-20 Journal: FEMS Microbiology Letters [Category] 살모넬라증, [키워드] bacteriophage therapy intravenous route Staphylococcus aureus typhoid [DOI] 10.1093/femsle/fnv242 [Article Type] journal-article