Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway
Article
[키워드] acute lung injury
analyzed
Anti-inflammation
Apoptosis
approved
attenuate
BALF
Bcl-xL
caspase
Cell
changes
China
confocal microscope
coronavirus
COVID-19
declined
downstream
drug
Effect
expression
fatal complication
flow cytometry
food
Granule
H1N1 influenza
histological
histopathological
IL-1β
IL-6
immunofluorescence
Infectious disease
Influenza virus
inhibited
injection
intrinsic
investigated
Jinhua Qinggan granules
LPS
lung
Lung injury
Lungs
material
mechanism
mice
Mild
mitochondrial apoptotic pathway
moderate
morbidity and mortality
MPO
neutrophil
Neutrophil apoptosis
novel coronavirus disease
Nuclear factor kappa-B
nuclei
p65
pathway
pharmacological
positive
proportion
Protein
protein concentration
protein expression
pulmonary inflammation
receptor
reduced
Respiratory disease
Respiratory virus infection
Signaling
signaling pathway
significantly
staining
survival
survival rate
TLR4
TNF-α
toll-like receptor 4
treated
Treatment
were assessed
were measured
[DOI] 10.1016/j.jep.2022.115763 PMC 바로가기
[DOI] 10.1016/j.jep.2022.115763 PMC 바로가기