Phylogenomics revealed migration routes and adaptive radiation timing of Holarctic malaria mosquito species of the Maculipennis Group계통유전체학은 마쿨리펜니스 그룹의 호라르틱 말라리아 모기 종의 이동 경로와 적응 방사 시기를 밝혀냈다.Article Published on 2023-04-102024-08-01 Journal: BMC Biology [Category] 말라리아, [키워드] Anopheles chromosomes introgression Maculipennis Subgroup Malaria vectors Migration mosquitoes Phylogenomics Species radiation [DOI] 10.1186/s12915-023-01538-w PMC 바로가기
Virus-derived variation in diverse human genomes다양한 인간 게놈의 바이러스 유래 변이Research Article Published on 2021-04-262022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acquisition addition Analysis applied biosafety can not cell line cell lines chromosomal chromosome chromosomes coevolution complex computational tool computational tools contributing to dataset described example expand experiment full-length gene conversion Gene Expression gene transfer generate genetic material Genetic variant Genetic variation Genome genome region Haplotype HERV HERV-K HHV-6 HIV-1 Host Human human endogenous retrovirus human endogenous retrovirus-K human endogenous retroviruses Human genome Human genomes human herpesvirus 6 Human immunodeficiency virus human T lymphotropic virus humans inaccessible include Infection introgression LCLs Linkage disequilibrium loci lymphoblastoid cell lymphoblastoid cell lines make up mapped nucleotide Perspective progenitor cell progenitor cells reads Reference materials sequence sequenced sequences Sequencing short-read sequencing Single nucleotide variant single nucleotide variants SMRV SNVs squirrel monkey squirrel monkey retrovirus Structural variant subjects SVs These cells transfer variant variants Variation virus virus infection viruses WGS whole genome Whole genome sequencing [DOI] 10.1371/journal.pgen.1009324 PMC 바로가기 [Article Type] Research Article
Radiation with reticulation marks the origin of a major malaria vector망상으로 표시된 방사선은 주요 말라리아 매개체의 기원을 나타냅니다.Article Published on 2020-12-152024-08-11 Journal: Microbial Cell Factories [Category] 말라리아, [키워드] adaptive radiation Anopheles funestus anopheline mosquito species complex introgression Reticulate evolution [DOI] 10.1073/pnas.2018142117 PMC 바로가기
Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago게놈 차원의 DNA 메틸화 및 유전자 발현 패턴은 인도네시아 군도 전체의 유전적 조상과 환경적 차이를 반영합니다.Research Article Published on 2020-05-262022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] admixture Analysis capture complex country CpG dataset differential expression differentially expressed disease Diversity DNA methylation driven by environmental factor European examined excluded expression expression level expression levels Gene Expression gene expression pattern Genetic genomic healthy individuals highlighting Host human populations humans identify immune function Immunity implication in healthy individuals individual Indonesia Infectious disease introgression involved island majority Methylation molecular Molecular medicine molecular pattern molecular phenotype Neanderthal New pathway Pathways Phenotypes Population promoter robust selective pressure Sequencing Sumba tested Transcription tropical understanding Variation [DOI] 10.1371/journal.pgen.1008749 PMC 바로가기 [Article Type] Research Article
Introgression from Domestic Goat Generated Variation at the Major Histocompatibility Complex of Alpine Ibex알파인 아이벡스의 주요 조직 적합성 복합체에서 국내 염소 생성 변이로부터의 이입Research Article Published on 2014-06-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptive allele alleles Alpine ibex balancing selection breed carried chromosomal region Clustering coding coding regions Defense Evidence functional gene genetic diversity Genetic polymorphism genetic variability Genetic variation genomes goat Haplotype haplotypes heterozygosity histocompatibility histocompatibility complex homozygous Ibex identify immune system individual introgression investigated involved loci locus Major major histocompatibility complex mechanism MHC non-coding region pathogen Pathogens polymorphism populations provide Research restored sequence sequenced Sequencing signature SNP SNP allele SNP alleles species Support susceptible thought two allele Two alleles Variation [DOI] 10.1371/journal.pgen.1004438 PMC 바로가기 [Article Type] Research Article
The Tomato Yellow Leaf Curl Virus Resistance Genes Ty-1 and Ty-3 Are Allelic and Code for DFDGD-Class RNA–Dependent RNA Polymerases토마토 황엽말림 바이러스 내성 유전자 Ty-1 및 Ty-3은 대립유전자이고 DFDGD-Class RNA-Dependent RNA 중합효소에 대한 코드입니다Research Article Published on 2013-03-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele alleles allelic amplification approach atypical DFDGD motif Author begomovirus begomovirus species Breeding catalytic DLDGD motif catalytic domain cause caused characterized chromosomal region chromosome chromosome 6 class code Combination described different disease geminivirus geminiviruses Gene gene functions genomic region inbred lines induced introgression leaf mapped marker mechanism molecular molecular markers Multiple plant plants RDR RDRα RDRα type RDRγ recent finding recent findings recombinant inbred lines recombination event Region related resistance resistance gene resistance genes resistance mechanism RNA RNA–dependent RNA polymerase shown Solanum chilense Solanum chilense –derived Ty-1 and Ty-3 genes specificity subtropical susceptible these viruses Tobacco Tobacco Rattle Virus tomato Tomato yellow leaf curl virus Tomato Yellow Leaf Curl Virus Disease transcriptional tropical Ty-1 Ty-1 and Ty-3 Ty-1/Ty-3 gene Ty-3 TYLCV virus Virus Disease viruses yellow [DOI] 10.1371/journal.pgen.1003399 PMC 바로가기 [Article Type] Research Article