Effects of Strain Differences, Humidity Changes, and Saliva Contamination on the Inactivation of SARS-CoV-2 by Ion IrradiationArticle Published on 2024-03-282024-09-05 Journal: Viruses [Category] update2024, [키워드] Humidity inactivation Ion Saliva SARS-CoV-2 VoC [DOI] 10.3390/v16040520 PMC 바로가기 [Article Type] Article
An integrated metabolomic and proteomic approach for the identification of covalent inhibitors of the main protease (Mpro) of SARS-COV-2 from crude natural extractsArticle Published on 2023-01-152022-11-15 Journal: Talanta [Category] SARS, 유전자 메커니즘, 치료제, [키워드] Analysis applied approach baicalein binding carried catalytic characteristic Chinese complementary complex Compound Covalent binder Cys145 database drug target electrophilic Final functional HIS163 HIS164 His41 independent inhibitor inhibitors Ion knowledge M pro M(pro) mass mass spectrometry maturation metabolomic metabolomics Michael molecular dynamics MPro nucleophilic peptide platform polyprotein protease protein-ligand Proteins proteomic proteomics residue SARS-CoV-2 Scutellaria baicalensis tested the SARS-CoV-2 [DOI] 10.1016/j.talanta.2022.123824 PMC 바로가기
Antiviral efficacy of cerium oxide nanoparticlesArticle Published on 2022-11-052022-11-15 Journal: Scientific Reports [Category] SARS, 치료제, [키워드] Antiviral antiviral activity antiviral efficacy candidate Concentration coronavirus SARS-CoV-2 cytotoxicity decrease Effect Efficacy evidenced expected gastroenteritis highest Influenza virus Ion mechanism MS2 bacteriophage Nanomaterial no decrease non-enveloped virus nonspecific plaque forming unit Registered released sensitivity significantly lower tested virus viruses were assessed [DOI] 10.1038/s41598-022-23465-6 PMC 바로가기
Hydrothermal assisted biogenic synthesis of silver nanoparticles: A potential study on virulent candida isolates from COVID-19 patientsArticle Published on 2022-10-062022-11-15 Journal: PLoS ONE [Category] 진단, [키워드] atomic biological activity Candida Candida albican Candida albicans Cell cell membrane coated COVID-19 COVID-19 patient effective Fourier transform High-resolution Ion isolate mechanism Microscopy Modification Morphological PCR question reduction silver nanoparticle TEM Testing thymus Till transmission electron microscopy virulence virulent vulgaris [DOI] 10.1371/journal.pone.0269864 PMC 바로가기
Evaluation of the relative potential for contact and doffing transmission of SARS-CoV-2 by a range of personal protective equipment materialsArticle Published on 2022-10-052022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome Adsorption aerosol analysed antiviral potency caused Community Contact coronavirus coronavirus disease correlation doffing Efficacy equipment evaluated global public health healthcare Infection Ion m/z negative correlation no correlation Personal protective equipment Physicochemical properties Polymer positive PPE Protective reduction in Regression model SARS-CoV-2 transmission the SARS-CoV-2 titre Transmission transmission of SARS-CoV-2 virion virus while [DOI] 10.1038/s41598-022-20952-8 PMC 바로가기
Structural Reshaping of the Zinc-Finger Domain of the SARS-CoV-2 nsp13 Protein Using Bismuth(III) Ions: A Multilevel Computational StudyArticle Published on 2022-10-032022-11-16 Journal: Inorganic chemistry [Category] COVID19(2023년), SARS, 변종, [키워드] analyses anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity classical decrease degrade domain Effect Efficacy Evidence evidenced extension feature Helicase hydrophobic immune Interaction Ion MD simulations MIF Modification molecular molecular interaction non-structural protein nsp12 protein nsp13 Occurrence pandemic Protein provide Research responsible SARS-COV-2 infection the SARS-CoV-2 the vaccine therapeutic strategy variants [DOI] 10.1021/acs.inorgchem.2c02685 PMC 바로가기
Low SARS-CoV-2 viral load among vaccinated individuals infected with Delta B.1.617.2 and Omicron BA.1.1.529 but not with Omicron BA.1.1 and BA.2 variantsArticle Published on 2022-09-202022-11-16 Journal: Frontiers in Public Health [Category] SARS, 변종, [키워드] Analysis Asymptomatic disease AZD1222 B.1.1.529 B.1.617.2 BBV152 Case-control Chennai Clinical characteristics clinical history Clustering Complete COVID-19 COVID-19 diagnosis COVID-19 severity Delta demographic characteristics disease Disease progression epidemiological Hospitalized Immune escape India individual Ion Lineage Mutation next generation sequencing number of comorbidities omicron Omicron BA.2 performed Phylogenetic analysis Phylogeny predict Randomly reported RT-PCR SARS-CoV-2 variant SARS-CoV-2 viral load selected selective sequence Severe case severe disease Spread strain System TaqPath unique vaccinated individual vaccine dose variant variants variants of SARS-CoV-2 virological marker virus strains was performed WGS [DOI] 10.3389/fpubh.2022.1018399 PMC 바로가기
Structural and Dynamic Insights into SARS-CoV-2 Spike-Protein-Montmorillonite InteractionsSARS-CoV-2 스파이크-단백질-몬모릴로나이트 상호작용에 대한 구조적 및 동적 통찰력Article Published on 2022-08-022022-09-11 Journal: Langmuir : the ACS journal of surfaces and colloid [Category] COVID19(2023년), SARS, 변종, [키워드] Cell cell entry Critical develop drug drug therapy dynamic effective electrostatic explicit glycan glycans help hydrophobic hydrophobic interaction hydrophobic interactions immune response insight Interaction interactions Ion mechanism Modification molecular dynamics Molecular dynamics simulation Montmorillonite nanoparticle pandemic performed probe Protein provide residue residues S protein SARS-CoV-2 therapeutic therapy Vaccine Vaccine development Vaccines variant virus world population [DOI] 10.1021/acs.langmuir.2c00837 PMC 바로가기 [Article Type] Article
Electrochemical immunosensors using electrodeposited gold nanostructures for detecting the S proteins from SARS-CoV and SARS-CoV-2SARS-CoV 및 SARS-CoV-2에서 S 단백질을 검출하기 위해 전기도금된 금 나노구조를 사용하는 전기화학적 면역센서Article Published on 2022-07-012022-09-11 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amperometry Analysis antibody capture carbon carried Complete Device Diagnosis electrode Features gold Gold nanoparticles group immunosensor Ion limit of detection MAA mercaptoacetic acid monolayer point-of-care proof proof of concept Protein protocol reduction S protein S proteins Saliva SAM SARS-CoV SARS-CoV-2 selectivity sensitivity target protein target proteins the S protein Volume was performed was tested [DOI] 10.1007/s00216-022-03956-1 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Whole-Genome Sequencing by Ion S5 Technology-Challenges, Protocol Optimization and Success Rates for Different StrainsIon S5 기술에 의한 SARS-CoV-2 전체 게놈 시퀀싱 - 다양한 균주에 대한 과제, 프로토콜 최적화 및 성공률Article Published on 2022-06-062022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Amplicon arise assigned cDNA Concentration construction COVID-19 COVID-19 pandemic demonstrated diagnostics Effectiveness Emergency genomic data idea immunization Ion less library library preparation lineages Modification molecular Molecular epidemiology mRNA mRNA or viral vector vaccines Mutation Next-generation sequencing NGS optimization Panel Patient Poland produced protocol Public public health emergency Rate Real-time PCR required RT-PCR SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 lineage SARS-CoV-2 sequencing Scientific community Sequencing strain Support Surveillance Thermo Fisher Scientific variant variants variants of concern Viral Viral load Viral RNA Viral vector vaccines whole-genome whole-genome sequencing [DOI] 10.3390/v14061230 PMC 바로가기 [Article Type] Article