Ultrasensitive Detection of COVID-19 Virus N Protein Based on p-Toluenesulfonyl Modified Fluorescent Microspheres Immunoassayp-톨루엔설포닐 변형 형광 미소구 면역분석법을 기반으로 한 COVID-19 바이러스 N 단백질의 초고감도 검출Article Published on 2022-06-222022-09-11 Journal: Biosensors [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] addition antibody buffer capture caused coronary pneumonia COVID-19 COVID-19 N protein COVID-19 virus detect detection Detection limit Fc region fluorescent fluorescent microspheres group hydrophobic immunochromatographic immunochromatographic assay Infection ionic strength Lateral lateral flow lateral flow immunochromatographic assay LFIA Ligand Mortality N protein p-toluenesulfonyl. pandemic Pneumonia Population screening promote reactive reactivity strip sulfhydryl tosyl [DOI] 10.3390/bios12070437 PMC 바로가기 [Article Type] Article
Teaching an old dog new tricks: A lipid membrane-based electric immunosensor for real-time probing of the spike S 1 protein subunit from SARS-CoV-2늙은 개에게 새로운 트릭 가르치기: SARS-CoV-2의 스파이크 S 1 단백질 소단위의 실시간 조사를 위한 지질막 기반 전기 면역 센서Article Published on 2022-03-012022-09-11 Journal: Proteomics [Category] SARS, 치료기술, [키워드] ACE2 Adsorption alteration amplitude Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody changes in core correlated Disease diagnosis early disease extraction followed by human serum in vitro Interaction ionic strength lipid membrane membrane membrane potential membrane potential. monoclonal antibody pathogen Pathogens point-of-care Protein Protein subunit Proteins receptor recorded SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike S1 serum proteins shown spectral analysis Spike protein subunit Teaching the SARS-CoV-2 transmembrane Transmembrane potential [DOI] 10.1002/pmic.202100047 PMC 바로가기 [Article Type] Article
Biochemical and biophysical characterization of the main protease, 3-chymotrypsin-like protease (3CLpro) from the novel coronavirus SARS-CoV 2신종 코로나바이러스 SARS-CoV 2의 주요 프로테아제인 3-키모트립신 유사 프로테아제(3CLpro)의 생화학적 및 생물물리학적 특성 규명Article Published on 2020-12-172022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 치료제, [키워드] 3CLpro Activation Alter analytical techniques antiviral drug target antiviral therapeutics biochemical Biochemistry Biophysical chemistry buffer buffer solution calculated candidate condition conditions coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Divalent drug enzymatic assay exhibited functional protein highest IMPROVE inhibitor inhibitors ionic strength kinetic lead less liberation maturation Novel coronavirus novel coronavirus disease parameter polyprotein processing protease reduced respiratory responsible salts SARS-CoV 2 SARS-CoV-2 setup Severe acute respiratory syndrome slope solubility stability thermodynamic Viral virus was recorded [DOI] 10.1038/s41598-020-79357-0 PMC 바로가기 [Article Type] Article
Ibuprofen, a traditional drug that may impact the course of COVID-19 new effective formulation in nebulizable solution분무 가능한 용액에서 COVID-19의 새로운 효과적인 제형의 과정에 영향을 미칠 수 있는 전통 약물, 이부프로펜Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 치료제, [키워드] 2019-nCoV 2019-nCoV infection absence Actin actin protein actin proteins Administered airway airways anti-inflammatory property Bacteria Bioavailability biological property Burkholderia caused Concentration contribute coronavirus Course COVID-19 demonstrated dose duplication Effect effective enveloped virus enzyme family filament health emergency hydrosoluble hypertonic Hypothesis ibuprofen include Infection inhibit Interaction investigator involved ionic strength kill local inflammation lung Lung inflammation Lungs membrane methicillin methicillin-resistant Staphylococcus aureus mucolytic nebulized NIH Other oxygen Pathogenesis people with COVID-19 physico-chemical properties physico-chemical property prevention strategies reactive oxygen species reactive oxygen specy reduce reduced reorganization required ROS SARS-CoV-2 Spread Staphylococcus aureus systemic inflammatory response systemic inflammatory responses therapeutic therapeutic effect virucidal virus virus infection water [DOI] 10.1016/j.mehy.2020.110079 PMC 바로가기 [Article Type] Article
Effects of solution conditions on characteristics and size exclusion chromatography of pneumococcal polysaccharides and conjugate vaccinesarticle Published on 2016-11-302024-09-01 Journal: Carbohydrate Polymers [Category] 폐렴구균 감염증, [키워드] capsular polysaccharide ionic strength pneumococcus Protein-polysaccharide conjugates size exclusion chromatography Vaccines [Article Type] article
Effect of electrostatic interactions on the ultrafiltration behavior of charged bacterial capsular polysaccharidesarticle Published on 2016-11-302024-09-01 Journal: Biotechnology Progress [Category] 폐렴구균 감염증, [키워드] capsular polysaccharide electrostatic interactions fouling ionic strength pneumococcus Ultrafiltration Vaccines [Article Type] article