SOCS1 Haploinsufficiency Presenting as Severe Enthesitis, Bone Marrow Hypocellularity, and Refractory Thrombocytopenia in a Pediatric Patient with Subsequent Response to JAK InhibitionCase Reports Published on 2022-11-012024-09-02 Journal: Journal of Clinical Immunology [Category] 대상포진, [키워드] Autoinflammatory syndrome Bone marrow hypocellularity Immune thrombocytopenia Interferonopathy JAK inhibition SOCS1 haploinsufficiency [DOI] 10.1007/s10875-022-01346-x PMC 바로가기 [Article Type] Case Reports
Management of Axial Spondyloarthritis – Insights into UpadacitinibReview Published on 2022-10-192024-09-04 Journal: Drug design, development and therapy [Category] 대상포진, [키워드] ankylosing spondylitis axial spondyloarthritis JAK inhibition Upadacitinib [DOI] 10.2147/DDDT.S330413 PMC 바로가기 [Article Type] Review
JAK inhibition as a new treatment strategy for patients with COVID-19Review article Published on 2022-08-012022-10-05 Journal: Biochemical pharmacology [Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료법, [키워드] AAK1 ACE-2 acute respiratory syndrome adverse outcomes angiotensin-converting enzyme 2 Bacterial infection blockers caused clinical trial clinical trials Combination coronavirus coronavirus disease Corticosteroids Course COVID-19 Critical cytokine Cytokine storm Cytokines Cytokines storm develop discharge Disease progression dysregulated effective Epidemic Future GAK greater herpes zoster Host ICU admission IL-2 IL-6 IL-6 receptor immune improve clinical outcome increased risk Infection Inflammation inhibit inhibiting involved Jak JAK inhibition JAK inhibitor Jak-STAT JAK/STAT JAK/STAT signaling janus medication medications Mortality MOST new treatment strategy offer pathway Patient patients with COVID-19 pro-inflammatory cytokine raised regulate released SARS-CoV-2 severe pneumonia significantly Spread Thromboembolic events TNF-α Transcription transmembrane protein Treatment upregulated viral endocytosis virus virus infection WHO guideline [DOI] 10.1016/j.bcp.2022.115162 [Article Type] Review article
JAK inhibition as a new treatment strategy for patients with COVID-19Review Published on 2022-07-032024-09-04 Journal: Biochemical pharmacology [Category] 대상포진, [키워드] COVID-19 Cytokines storm Inflammation JAK inhibition Jak-STAT SARS-CoV-2 [DOI] 10.1016/j.bcp.2022.115162 PMC 바로가기 [Article Type] Review
Emerging Topical and Systemic JAK Inhibitors in DermatologyReview Published on 2019-12-032024-09-02 Journal: Frontiers in immunology [Category] 대상포진, [키워드] autoimmune skin diseases Immunopathogenesis inflammatory skin diseases JAK (Janus kinase) JAK inhibition JAK/STAT pathway pathophysiology [DOI] 10.3389/fimmu.2019.02847 PMC 바로가기 [Article Type] Review
Overcoming treatment challenges in myelofibrosis and polycythemia vera: the role of ruxolitinibReview Article Published on 2016-03-262024-09-02 Journal: Cancer chemotherapy and pharmacology [Category] 대상포진, [키워드] JAK inhibition myelofibrosis myeloproliferative neoplasm polycythemia vera ruxolitinib [DOI] 10.1007/s00280-016-3012-z PMC 바로가기 [Article Type] Review Article