P16-CD8-Ki67 Triple Algorithm for Prediction of CDKN2A Mutations in Patients with Multiple Primary and Familial MelanomaArticle Published on 2024-04-132024-09-05 Journal: Diagnostics [Category] update2024, [키워드] CD8 CDKN2A familial melanoma Ki67 multiple primary melanoma P16 [DOI] 10.3390/diagnostics14080813 PMC 바로가기 [Article Type] Article
AMEERA-4: a randomized, preoperative window-of-opportunity study of amcenestrant versus letrozole in early breast cancerarticle Published on 2023-11-102024-09-05 Journal: Breast Cancer Research : BCR [Category] update2024, [키워드] Amcenestrant Early breast cancer Ki67 postmenopausal Window-of-opportunity study [DOI] 10.1186/s13058-023-01740-2 PMC 바로가기 [Article Type] article
Inhibition of MEK signaling prevents SARS-CoV2-induced lung damage and improves the survival of infected miceArticle Published on 2022-12-012023-07-10 Journal: Journal of medical virology [Category] COVID19(2023년), [키워드] COVID-19 ERK phosphorylation Ki67 lung MEK mouse model SARS-CoV-2 [DOI] 10.1002/jmv.28094 PMC 바로가기
A diminished immune response underlies age-related SARS-CoV-2 pathologies감소된 면역 반응은 연령 관련 SARS-CoV-2 병리의 기초가 됩니다Article Published on 2022-06-282022-09-12 Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Adaptive immune response advanced age aging B cell Bcl6 cause Ccr6 characterization Cohort Comorbidity COVID-19 CP: Immunology elevated FOXP3 hamsters host response IL-17 immune response Immunity increase in Ki67 Lungs morbidity Mortality MPO Neutralizing antibodies neutrophil Neutrophils Older pathology phenotype Post-infection reduced respiratory tract resulting SARS-CoV-2 SARS-COV-2 infection significantly Support suppressor T cells. T cell TGF-β These data tissue repair virus [DOI] 10.1016/j.celrep.2022.111002 PMC 바로가기 [Article Type] Article
Merkel cell carcinoma presenting as a malignant pleural effusion post-COVID-19 hospitalization: A case report and literature review코로나19 입원 후 악성 흉막삼출액으로 나타난 메르켈세포암: 증례보고 및 문헌고찰Case Reports Published on 2022-01-012022-09-12 Journal: Diagnostic cytopathology [Category] SARS, 진단, [키워드] Case report CD45 CD56 Cell cells chromatin chromogranin Cluster COVID-19 cytoplasm demonstrated diagnosed English FIVE fluid cytology Hospitalization hyperchromatic nuclei Immunosuppression Immunosuppressive treatment Ki67 knowledge literature review Lymphocytes Macrophage male MCC medium Merkel cell carcinoma Merkel cell polyomavirus neuroendocrine Patient pleural effusion Pneumonia positive presenting proliferative receiving reported Respiratory failure steroid treatment synaptophysin Tocilizumab Tumor UV light was done [DOI] 10.1002/dc.24882 PMC 바로가기 [Article Type] Case Reports
Analysis of the Long-Term Impact on Cellular Immunity in COVID-19-Recovered Individuals Reveals a Profound NKT Cell ImpairmentCOVID-19에서 회복된 개인의 세포 면역에 대한 장기적인 영향 분석은 심각한 NKT 세포 손상을 보여줍니다Research Article Published on 2021-04-272022-09-10 Journal: mBio [Category] MERS, SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected analyzed caused CD4 CD4 and CD8 T cells CD8 T cell CD8 T cells Cell cell death cells cellular cellular immunity characterized Concomitant convalescence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19-convalescent individual COVID-19-convalescent individuals cytokine Cytokines decrease defined disease expression frequencies Frequency granzyme B GzmB immune signature immune system immunological change immunological changes Impact increase in increases in individual Interaction Ki67 Ki67 expression mononuclear cell mononuclear cells NKT NKT cell pandemic Patient Peripheral blood Peripheral blood mononuclear cells proliferate reduction in Regulatory Regulatory T cell respiratory SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus Significant significant decrease significantly sustained T cell T cell receptor T cells TCR the disease the patient while Wuhan [DOI] 10.1128/mBio.00085-21 PMC 바로가기 [Article Type] Research Article
The Gastrointestinal Tract Is an Alternative Route for SARS-CoV-2 Infection in a Nonhuman Primate Model위장관은 비인간 영장류 모델에서 SARS-CoV-2 감염에 대한 대체 경로입니다Article Published on 2021-04-012022-09-11 Journal: Gastroenterology [Category] MERS, SARS, 바이오마커, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 caspase 3 caused CD68 Chain Reaction change cleaved Clinical sign Clinical signs connection coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytokine Cytokines digestive dysfunction evaluated fecal Fecal-Oral Route Gastrointestinal GI Tract goblet cells Histopathology host responses Hypothesis immunohistochemistry increased expression increasingly Infection Inflammation Inflammatory cytokines inoculation intranasal investigated involved Ki67 lung macrophages manifestation Model mucin NHP Pathogenesis pathogenesis of COVID-19 pathogenesis of SARS-CoV-2 pathologic Patient periodic acid Pneumonia polymerase chain polymerase chain reaction primate quantified Quantitative reported respiratory respiratory tissue respiratory tissues response reverse transcription rhesus Rhesus monkeys route SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe infections staining tissue tissues tract Viral viral genomic RNA viral infection were infected were recorded [DOI] 10.1053/j.gastro.2020.12.001 PMC 바로가기 [Article Type] Article
Nicotine Changes Airway Epithelial Phenotype and May Increase the SARS-COV-2 Infection Severity니코틴은 기도 상피 표현형을 변화시키고 SARS-COV-2 감염 심각도를 증가시킬 수 있습니다Article Published on 2020-12-282022-09-12 Journal: Molecules [Category] MERS, SARS, 진단, [키워드] ACE2 Activation agar ATP blue Cell Cell migration cell proliferation cell viability cellular change cigarette Concentration EGFR ELISA EMT evaluated Evidence exclusion exposure to growth implicated increase increase in Infection involved Ki67 Migration mimicking mitochondrial dysfunction molecular nAChR Nicotine over-expression proliferation reduction SARS-CoV-2 SARS-COV-2 infection senescence severity substrate treated trypan blue VEGF viability viral infection western blotting [DOI] 10.3390/molecules26010101 PMC 바로가기 [Article Type] Article
Evidence-based guidelines for managing patients with primary ER+ HER2− breast cancer deferred from surgery due to the COVID-19 pandemicArticle Published on 2020-06-082022-10-04 Journal: NPJ Breast Cancer [Category] 바이오마커, 유전자 메커니즘, 임상, 치료법, [키워드] Algorithm Analysis Breast cancer Cell Chemotherapy Course COVID-19 crisis COVID-19 pandemic Diagnosis Endocrine Guidance indicate International Ki67 Patient patients positive Support surgical therapy three group Treatment Trial Tumor [DOI] 10.1038/s41523-020-0168-9 PMC 바로가기 [Article Type] Article
Effect of homeostatic T-cell proliferation in the vaccine responsiveness against influenza in elderly peopleResearch Published on 2019-07-052024-09-02 Journal: Immunity & Ageing : I & A [Category] 대상포진, [키워드] Inflammation Ki67 Thymic function TREC Treg [DOI] 10.1186/s12979-019-0154-y PMC 바로가기 [Article Type] Research