Immunogenicity Parameters of Cancer Patients Receiving the mRNA Vaccine BNT162b2 While Obtaining Radiotherapy: A Longitudinal Cohort EvaluationArticle Published on 2024-03-062024-09-05 Journal: Vaccines [Category] update2024, [키워드] antibody persistence COVID-19 humoral immune response kinetic Seroconversion Side effects [DOI] 10.3390/vaccines12030275 PMC 바로가기 [Article Type] Article
The Wood equation allows consistent fitting of individual antibody-response profiles of Zika virus or SARS-CoV-2 infected patientsResearch Article Published on 2023-11-072024-09-05 Journal: Heliyon [Category] update2024, [키워드] Curve fit humoral immune response kinetic SARS-CoV-2 Wood equation Zika virus [DOI] 10.1016/j.heliyon.2023.e21945 PMC 바로가기 [Article Type] Research Article
Prolonged replication of BA.1 and BA.2 Omicron lineages compared to Delta variant in nasopharyngeal samples from COVID-19 patientsCOVID-19 환자의 비인두 샘플에서 델타 변종에 비해 BA.1 및 BA.2 오미크론 계통의 장기 복제Article Published on 2023-02-012023-07-10 Journal: Infectious diseases now [Category] COVID19(2023년), [키워드] BA.1 BA.2 kinetic SARS-CoV-2 Viral load [DOI] 10.1016/j.idnow.2022.10.001 PMC 바로가기
Onset and window of SARS-CoV-2 infectiousness and temporal correlation with symptom onset: a prospective, longitudinal, community cohort studyArticle Published on 2022-11-012022-11-15 Journal: The Lancet. Respiratory Medicine [Category] SARS, 변종, 치료기술, [키워드] accelerate Alpha assessment assumption Bayesian Cohort cohort study Community Contact correlation Course COVID-19 COVID-19 case determine diagnosed early diagnosis eight eligible enrolled Evidence Final Guidance Hierarchical High-resolution household index cases Infection infection control Infectious virus initial IQR Isolation kinetic Lateral flow device LFD median Older Onset participant PCR positive PCR-confirmed plaque-forming unit post-symptom onset Probability quantified real-world data recruitment reduced released RT-PCR SARS-CoV-2 Self-isolation sensitivity Seven study population suggested Support survival Symptom symptom onset Symptoms the median the SARS-CoV-2 to define Transmission upper respiratory tract variant viral growth Viral load viral replication Viral RNA viral RNA load viral shedding virus were assessed [DOI] 10.1016/S2213-2600(22)00226-0 PMC 바로가기
Observational Study of Receptor Binding Domain Spike Antibody Responses to 3 SARS-CoV-2 Vaccinations in Noninfected Subjects: Parallel Neutralizing Antibody and Cardiac Troponin I and T ObservationsArticle Published on 2022-10-292022-11-15 Journal: The journal of applied laboratory medicine [Category] COVID19(2023년), SARS, 진단, [키워드] antibody Biotechnology blood specimen cardiac cardiac troponin change collected Concentration concentrations Decline dose doses Effectiveness ET Healthcare increase janssen kinetic Moderna myocardial injury Neutralizing observation Pfizer platform point-of-care postvaccination Protein Pylon 3D RBD Receptor binding domain response SARS-CoV-2 seronegative specimens spike subject subjects troponin vaccination Vaccinations Vaccine were measured [DOI] 10.1093/jalm/jfac053 PMC 바로가기
Kinetics of Drug Molecule Interactions with a Newly Developed Nano-Gold-Modified Spike Protein Electrochemical Receptor SensorArticle Published on 2022-10-172022-11-15 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplification antiviral drug Chloroquine compounds Concentration correlated COVID-19 Detection sensitivity Developed docking drug drug target drugs electrochemical receptor biosensor exhibit Gln group Hydrogen bond Hydroxychloroquine Interaction investigated kinetic Kinetics limit of detection linear linkage allosterism molecule pandemic Protein provide receptor reported Research residue SARS-CoV-2 sensor Seven spike Spike protein the SARS-CoV-2 the spike protein Treatment was used WHO World Health Organization [DOI] 10.3390/bios12100888 PMC 바로가기
Amplitudes and kinetic of antibodies after second and third doses of BNT162b2 vaccine in nonagenarians and centenarians with and without prior SARS-CoV-2 infectionArticle Published on 2022-10-012022-11-15 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 진단, [키워드] antibody dose kinetic of BNT162b2 SARS-COV-2 infection Vaccine [DOI] 10.1016/j.cmi.2022.05.025 PMC 바로가기
In Silico Evaluation of Sesquiterpenes and Benzoxazinoids Phytotoxins against Mpro, RNA Replicase and Spike Protein of SARS-CoV-2 by Molecular Dynamics. Inspired by NatureArticle Published on 2022-08-292022-11-15 Journal: Toxins [Category] SARS, 치료제, [키워드] active against added addition Analysis antiviral activities benzoxazinoid calculated candidate complex complexes Compound COVID-19 derivative derivatives described docking docking score Dynamics ENhance evaluated fluctuation generate Hydrogen bond in silico interactions kinetic M pro molecular molecular docking molecular dynamics MPro Nature Phytotoxin protease Protein protein-ligand replicase RMSD RNA SARS-CoV-2 selected Sesquiterpene shown spike spike glycoprotein Spike protein stability tested the spike protein virus were assessed [DOI] 10.3390/toxins14090599 PMC 바로가기
Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main proteaseSARS-CoV-2 주요 프로테아제의 신규 억제제로서의 2-(푸란-2-일메틸렌)히드라진-1-카르보티오아미드 유도체의 발견Article Published on 2022-08-052022-09-11 Journal: European journal of medicinal chemistry [Category] COVID19(2023년), SARS, 치료제, [키워드] 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives Compound COVID-19 cytotoxicity demonstrated derivative drug design drug target furan Health house inhibitor inhibitors of SARS-CoV-2 kinetic library screening M pro main protease mass spectrometry MDCK cells Non-peptidomimetic inhibitors protease SARS-CoV-2 starting point Treatment treatment of COVID-19 Vero [DOI] 10.1016/j.ejmech.2022.114508 PMC 바로가기 [Article Type] Article
Kinetics of the SARS-CoV-2 Antibody Avidity Response Following Infection and Vaccination감염 및 백신 접종 후 SARS-CoV-2 항체 결합력 반응의 역학Article Published on 2022-07-082022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Algorithm antibody Antibody avidity antibody levels Antibody Response Antibody responses avidity Cohort coronavirus COVID-19 pandemic Critical domain Epidemics estimation FIVE healthcare worker Healthcare workers IgA IgA antibodies IgA antibody IgG Including Inclusion Infection information kinetic Kinetics multiplex Multiplex assay nucleocapsid nursing home performed RBD respiratory response SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection Serological assay serological assays serology severe acute respiratory syndrome Coronavirus spike subunit the SARS-CoV-2 time since infection vaccination waned while [DOI] 10.3390/v14071491 PMC 바로가기 [Article Type] Article