Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strainsArticle Published on 2022-10-032022-11-16 Journal: World journal of microbiology & biotechnology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Amikacin analyzed antibiotic Antibiotic-resistance Antibiotics Bacteria Bacterial infection Bacterial infections calculated Cell cholesterol Concentration Coverage cytotoxicity drug resistance drug-resistant evaluated Gene Expression highest hospitalized patients IMPROVE inhibited Klebsiella Klebsiella pneumoniae less MBC MDR mechanism mRNA expression multi-drug resistant Niosome Niosome. occur positive ranged reduced SARS-CoV-2 significantly Spread stability strain Strains Toxicity Treatment were measured [DOI] 10.1007/s11274-022-03405-2 PMC 바로가기
Predictors of carbapenem-resistant Enterobacteriaceae (CRE) strains in patients with COVID-19 in the ICU ward: a retrospective case-control studyArticle Published on 2022-10-012022-11-16 Journal: The Journal of international medical research [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval acquisition acute respiratory syndrome Admission carbapenem carbapenem-resistant Enterobacteriaceae Care case-control study coronavirus corticosteroid treatment COVID-19 COVID-19 patient COVID-19 patients death determine enrolled Enterobacteriaceae hazard ratio ICU identify increased the risk independent risk factor Infection Invasive mechanical ventilation isolate Klebsiella Length majority Mortality mortality data Odds ratio Patient patients with COVID-19 patients without COVID-19 retrospective risk risk factor Risk factors significantly higher strain subdistribution Treatment two groups [DOI] 10.1177/03000605221129154 PMC 바로가기
Activity of ertapenem/zidebactam (WCK 6777) against problem EnterobacteralesArticle Published on 2022-09-302022-11-16 Journal: Journal of Antimicrobial Chemotherapy [Category] SARS, 비임상, [키워드] 1:1 active against activity administration breakpoint Dilution E. coli Escherichia coli evaluated experiments group healthcare increasingly indicated Infection inhibited isolate Klebsiella KPC Laboratory material MDR National nosocomial Outpatient over Parenteral pathogen Patient proportion regimen SARS-CoV-2 secondary submitted Support susceptibility Trial will drive [DOI] 10.1093/jac/dkac280 PMC 바로가기
Temporal dynamics of oropharyngeal microbiome among SARS-CoV-2 patients reveals continued dysbiosis even after Viral Clearance Research Published on 2022-08-242022-10-05 Journal: NPJ Biofilms and Microbiomes [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome administration Antibiotics Azithromycin Bacteria Bacterial infection Bacterial sepsis bacterial species Chryseobacterium clinical Clinical diagnosis clinically commensal bacteria compensated Complication complications Coronavirus-2 elevated feature Firmicute global public health healthy controls Human include indicate individuals Infection Influenza Klebsiella lung Lung infection microbial Microbiome morbidity and mortality observation oral organism Oropharyngeal oropharynx outbreak pandemic persist Pneumonia present proportion Proteobacteria reduced respiratory virus response reveal SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 positive individual secondary bacterial infection Sepsis shown stability Temporal the patient viral clearance [DOI] 10.1038/s41522-022-00330-y [Article Type] Research
Multidrug-Resistant Klebsiella pneumoniae in a Patient with SARS-Cov-2 Pneumonia in an Intensive Care Unit in Guayaquil, Ecuador: A Case Report에콰도르 Guayaquil의 중환자실에서 SARS-Cov-2 폐렴 환자의 다제내성 Klebsiella pneumoniae: 증례 보고Case Reports Published on 2022-07-222022-09-11 Journal: The American journal of case reports [Category] COVID19(2023년), SARS, 치료기술, [키워드] Admission admitted to ICU antibiotic Antibiotics Bacterial Blood blood culture broad-spectrum antibiotic carbapenem case study Chain Reaction Chest computed tomography Comorbidities Computed tomography Corticosteroid corticosteroid treatments Corticosteroids COVID-19 COVID-19 pandemic Culture Department Dyspnea Emergency emergency department ESBL health problem ICU ICUs incidence increase in intensive care unit intensive care units intravenously Invasive mechanical ventilation Klebsiella Klebsiella pneumoniae Klebsiella pneumoniae carbapenemase KPC Laboratory management medical history meropenem microorganism multidrug-resistant Nasopharyngeal swab NDM New past medical history pathogen Pathogens Patient polymerase chain polymerase chain reaction positive public health pulmonary infiltrate report reported reverse transcription risk factor Risk factors RT-PCR SARS-CoV2 secretion strain superinfection Swab tracheal Treatment use of corticosteroids vancomycin [DOI] 10.12659/AJCR.936498 PMC 바로가기 [Article Type] Case Reports
Pulmonary bacterial infections in adult patients hospitalized for COVID-19 in standard wardsObservational Study Published on 2022-06-012022-10-05 Journal: Infectious diseases now [Category] COVID19(2023년), SARS, 임상, [키워드] antibiotic use Antigen Bacteria Bacterial Bacterial infection bacteriological Blood Bordetella pertussis Bronchoalveolar lavage Characteristics Clinical data Co-infection collected conducted coronavirus cough COVID-19 COVID-19 pandemic CT-scan cultures diagnosed Enterococcus Fever France hospital hospitalized patients Infection Klebsiella Laboratory Legionella management median medical records Modification Mycoplasma nasopharyngeal occurred Oxygen requirement Patient patients hospitalized PCR PCR test pneumococcal Pneumonia positive Pseudomonas aeruginosa pulmonary retrospective SARS-CoV-2 screened Secondary infection sputum sputum samples Staphylococcus aureus Streptococcus pneumoniae with COVID-19 [DOI] 10.1016/j.idnow.2021.12.001 PMC 바로가기 [Article Type] Observational Study
Case Report: Next-Generation Sequencing in Diagnosis of Atypical Aspiration Pneumonia증례 보고: 비정형 흡인성 폐렴 진단의 차세대 염기서열분석Case Reports Published on 2022-01-042022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected air bronchogram aspiration aspiration pneumonia BALF Bronchoalveolar lavage fluid bronchogram Case report Chest chest CT scan clinical history consolidation Corona coronavirus cough COVID-19 COVID-19 pneumonia Diagnosis differential diagnosis early diagnosis fatigue Fever GGO ground-glass opacity IMPROVE in some Infection interlobular septal thickening intralobular intravenous antibiotics Klebsiella lung Misdiagnosis myalgia next generation sequencing—NGS Next-generation sequencing NGS nucleic acid nucleic acid sequences opacity other diseases pandemic Patient physician Pneumonia Prognosis radiologic radiological radiological improvement reported respiratory reverse transcription-PCR right lung risk RT-PCR SARS-CoV-2 sequence severe acute respiratory syndrome Coronavirus similarity Symptom the patient therapy Treatment upper lobe Virus Disease was performed [DOI] 10.3389/fpubh.2021.771154 PMC 바로가기 [Article Type] Case Reports
The prevalence of early‐ and late‐onset bacterial, viral, and fungal respiratory superinfections in invasively ventilated COVID‐19 patientsResearch Article Published on 2022-01-042022-10-04 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] Aspergillus fumigatus Bacteria Bacterial Bronchoalveolar lavage chronic obstructive Cohort coronavirus disease Coronavirus disease 2019 correlation COVID‐19 COVID‐19 patient Day develop Diabetes Mellitus fungal fungal pathogen herpes simplex Infection intensive care intubation invasive ventilation invasively ventilated patient investigated Klebsiella Klebsiella pneumoniae mechanical ventilation obesity pathogen Pathogens Patient Pneumonia Prevalence prevalent Probability Pseudomonas aeruginosa pulmonary disease respiratory coinfections respiratory virus severe acute respiratory syndrome coronavirus 2 significantly higher tested Ventilated virus [DOI] 10.1002/jmv.27548 PMC 바로가기 [Article Type] Research Article
Reduced transmission of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-KP) in patients with haematological malignancies hospitalized in an Italian hospital during the COVID-19 pandemicBrief Report Published on 2021-12-172022-10-29 Journal: JAC-Antimicrobial Resistance [Category] COVID-19, [키워드] acquisition Administered Aggressive analysed applied bloodstream infection BSI characterized clinical complication Consumption COVID-19 COVID-19 pandemic Effect effort eight evaluated hospital Hospitalized hospitalized patient hospitalized patients Italian Italy Klebsiella Klebsiella pneumoniae lockdown malignancies malignancy measure nosocomial objective outcome Patient patients patients hospitalized patients with haematological Pneumonia pneumoniae positive Prevent prevented reduced Result SARS-COV-2 infection SARS-CoV-2 transmission Seven significantly Spread Transmission two group [DOI] 10.1093/jacamr/dlab167 PMC 바로가기 [Article Type] Brief Report
Bacterial superinfection in adults with COVID-19 hospitalized in two clinics in Medellín-Colombia, 2020Research Article Published on 2021-07-132022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] adjusted association Bacteria bacterial superinfection bacterial superinfections Care clinical conditions clinics Comorbidities Complication complications COVID-19 cross determine diagnosed with COVID-19 distribution Encephalopathy Factor Generalized linear model groups Hospital stay Hospitalization Hospitalized Infection Klebsiella Lung disease mechanical ventilation morbidity and mortality multivariate adjustment Patient pneumoniae Prevalence prevalence ratio public health risk factor RT-PCR Sociodemographic Staphylococcus aureus steroid treatment variable with COVID-19 [DOI] 10.1371/journal.pone.0254671 PMC 바로가기 [Article Type] Research Article