Peripartum anesthetic management of women with SARS-CoV-2 infection in eight medical centers across three European countries: prospective cohort observation studyObservational Study Published on 2022-12-012023-07-06 Journal: The journal of maternal-fetal & neonatal medicine [Category] COVID19(2023년), [키워드] Anesthesia complications COVID-19 Infection labor Pneumonia Pregnancy [DOI] 10.1080/14767058.2021.1937105 [Article Type] Observational Study
Comparison of commercial SARS-CoV-2 surrogate neutralization assays with a full virus endpoint dilution neutralization test in two different cohorts두 개의 다른 코호트에서 상용 SARS-CoV-2 대리 중화 분석과 전체 바이러스 종말점 희석 중화 테스트의 비교Article Published on 2022-09-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] ACE2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody Antibody titers biosafety level Cohort cohorts convalescent Convalescent SARS-CoV-2-infected individuals COVID COVID vaccinated individuals Cutoff detect Determination Dilution Endpoint Full virus neutralization test glycoprotein gold gold standard indicate infected individuals Infection Interaction labor labor-intensive level 3 neutralization Neutralization assay neutralization test neutralization tests Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers Qualitative quantitative measurement RBD Receptor binding domain receptor protein Replication SARS-CoV-2 SARS-CoV-2-infected individual spike glycoprotein surrogate surrogate virus neutralization test sVNT the RBD vaccinated individuals Viral viral spike virus Virus neutralization virus neutralization test VNT [DOI] 10.1016/j.jviromet.2022.114569 PMC 바로가기 [Article Type] Article
Resolving SARS-CoV-2 CD4 + T cell specificity via reverse epitope discovery역 에피토프 발견을 통한 SARS-CoV-2 CD4 + T 세포 특이성 해결Meta-Analysis Published on 2022-08-162022-09-11 Journal: Cell Reports Medicine [Category] COVID19(2023년), SARS, 치료기술, [키워드] Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen approach CD4 CD4 T cells Cluster coronavirus COVID-19 dataset detect epitope epitope discovery FIVE functional cell HLA identify immunodominant individual infected individuals information Intensive labor leukocyte Meta-analysis pathogen peptide peptide pool public T cell response. recognizing responses SARS-CoV-2 sequence similarity severe acute respiratory syndrome Coronavirus similarity single-cell specificity T cell T cell receptor T cell receptors T cell response T cells TCR TCR repertoire TCRs These data transgenic utility [DOI] 10.1016/j.xcrm.2022.100697 PMC 바로가기 [Article Type] Meta-Analysis
The Risk of Obstetrical Hemorrhage in Placenta Praevia Associated with Coronavirus Infection Antepartum or Intrapartum코로나바이러스 감염과 관련된 근위태반의 산과 출혈 위험 분만 전 또는 분만 중Article Published on 2022-07-272022-09-11 Journal: Medicina [Category] COVID19(2023년), SARS, 치료기술, [키워드] analyzed antepartum Birth bleeding Childbirth Complication conducted COVID driven by evaluate first trimester group hemorrhage Hemostasis histological change Hospitalization hypertension identify incidence increase infected patients Infection intrapartum labor material no infection objective obstetrical bleeding occurred Patient patients Placenta placenta accreta placenta previa placenta previa. Pregnancy pregnancy-induced hypertension Prematurity presenting Result Retrospective study risk SARS-CoV-2 SARS-COV-2 infection severity significantly Signs and symptoms similarities specific treatment statistically significant difference stratified Symptoms three groups time of delivery viral disease viral infection with infection [DOI] 10.3390/medicina58081004 PMC 바로가기 [Article Type] Article
Performance of the TaqMan COVID-19 Pooling Kit for detection of SARS-CoV-2 in asymptomatic and symptomatic populations무증상 및 유증상 집단에서 SARS-CoV-2 검출을 위한 TaqMan COVID-19 풀링 키트의 성능Article Published on 2022-06-102022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Algorithm analytical sensitivity applicability Asymptomatic Asymptomatic case Asymptomatic cases Asymptomatic COVID-19 Chain Reaction China clinical clinical evidence Cohort cohorts coronavirus coronavirus disease COVID-19 curated demonstrated detect effective Evidence expected FIVE Frame gold gold standard higher education independent t-test labor lack nare nucleocapsid Open reading frame ORF ORF1ab P-value p-values pandemic PCR testing performance performed polymerase chain polymerase chain reaction pool pooling Population positive sample Prevalence Qualitative reported resource reverse transcriptase RNA RT-PCR RT-qPCR SARS-CoV-2 severe acute respiratory syndrome Coronavirus strain supported surveillance testing Swab symptomatic symptomatic and asymptomatic t-test TaqMan transcriptase Volume Wuhan [DOI] 10.1371/journal.pone.0269798 PMC 바로가기 [Article Type] Article
Single-cell transcriptomic profiling of lung endothelial cells identifies dynamic inflammatory and regenerative subpopulations폐 내피 세포의 단일 세포 전사체 프로파일링은 동적 염증 및 재생 하위 집단을 식별합니다Article Published on 2022-06-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), SARS, 신종인플루엔자, 유전자 메커니즘, [키워드] Activation Bacterial infections baseline Cell Clustering defined demonstrated division endothelial endothelial cells Endothelium expression Gene Expression H1N1 H1N1 influenza H1N1 influenza virus heterogeneity identify immune response gene immune response genes increased expression infected with SARS-CoV-2 Infectious disease Inflammatory inflammatory lung injury inflammatory signaling Influenza Injury labor limit LPS lung lung endothelial Lung injury MHC gene MHC genes murine organ overexpression Pathway analysis performed phenotypic prevented proliferative promote Pulmonology regeneration regenerative respond Seurat single-cell single-cell RNA-seq Sox17 subpopulation targeted therapy transcriptomic Vascular vascular bed vascular endothelial cell vascular endothelial cells virus [DOI] 10.1172/jci.insight.158079 PMC 바로가기 [Article Type] Article
Emergency SARS-CoV-2 variants of concern: rapidly direct RT-qPCR detection without RNA extraction, clinical comparison, cost-effective, and high-throughput우려되는 긴급 SARS-CoV-2 변종: RNA 추출 없이 신속하게 직접 RT-qPCR 검출, 임상 비교, 비용 효율적 및 높은 처리량Article Published on 2022-06-022022-09-11 Journal: Aging (Albany NY) [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alternative method analytical sensitivity Chain Reaction characterized complex coronavirus coronavirus disease Coronavirus disease 2019 cost-effective diagnosis COVID-19 Diagnosis direct RT-qPCR dominant E gene Emergency Evolution faster gold gold standard High-throughput labor limit of detection mutations nasopharyngeal swabs Negative predictive value pandemic polymerase chain polymerase chain reaction positive Predictive value protocol real-time reverse transcriptase Real-time reverse transcriptase polymerase chain reaction reverse transcriptase Reverse transcriptase polymerase chain reaction RNA extraction RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 VoC sensitivity severe acute respiratory syndrome Coronavirus significantly Spike protein thermocyclers variant variants variants of concern [DOI] 10.18632/aging.204095 PMC 바로가기 [Article Type] Article
Failure to Detect SARS-CoV-2 RNA in the Air During Active Labor in Mothers Who Recently Tested Positive최근에 양성 판정을 받은 산모의 분만 중 공기 중 SARS-CoV-2 RNA 감지 실패Article Published on 2022-04-272022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 치료기술, [키워드] Aerosol generation Birth carried collected coronavirus COVID detect evaluate Evidence failure initial investigated isolation rooms labor Labor and delivery limit of detection Mask Masks mother Negative pressure Patient positive Positive test provide Respiratory droplets risk SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission tested the patient Transmission transmission of SARS-CoV-2 vaginal delivery Ventilation Viral transmission [DOI] 10.3389/fpubh.2022.881613 PMC 바로가기 [Article Type] Article
The prevalence of nurse burnout and its association with telomere length pre and during the COVID-19 pandemic간호사 번아웃의 유병률과 COVID-19 전염병 이전 및 동안 텔로미어 길이와의 연관성Article Published on 2022-03-162022-09-11 Journal: PLoS ONE [Category] 유전자 메커니즘, [키워드] Administered Analysis analyzed Appropriate association Biomarker Blood blood sample Blood samples Burnout Care cellular change characterized collected coronavirus disease Coronavirus disease 2019 correlation Correlation analysis COVID-19 COVID-19 pandemic cross-sectional cross-sectional study Data collection decrease delivery demographics Depersonalization determine Effect Emotional exhaustion Epigenetic Final Health healthcare Healthcare system Healthcare systems hospital IMPROVE indicate Intervention inventory labor measure mechanism mental health Multiple regression analysis normality Nurse Nurses nursing care pandemic participant participated Patient care physical Prevalence prevalent promote Psychological reduced room Stress Symptom Symptoms syndrome telomere the mean took place two group unit was measured [DOI] 10.1371/journal.pone.0263603 PMC 바로가기 [Article Type] Article
Rapid electrochemical immunodetection of SARS-CoV-2 using a pseudo-typed vesicular stomatitis virus model유사형 수포성 구내염 바이러스 모델을 사용한 SARS-CoV-2의 신속한 전기화학적 면역 검출Article Published on 2022-03-012022-09-11 Journal: Talanta [Category] MERS, SARS, 진단, 치료기술, [키워드] alternative Antigen applicability applied binding Biochip biosensor complex Concentration contribute costly COVID-19 COVID-19 pandemic COVID-19 test COVID-19 tests demonstrated diagnostic diagnostic testing diagnostic tests diagnostics Electrochemical impedance spectroscopy equipment exhibiting feasible Immunosensors integration Intensive labor labor-intensive limitation monoclonal antibodies monoclonal antibody overcome Particle performed plague platform point of care Protein pseudovirus Quantitative Rapid Rapid diagnostic testing real-time RT-PCR RT-PCR RT-PCR test RT-PCR tests S1 protein SARS-CoV-2 SARS-CoV-2 pseudovirus SARS-CoV-2 pseudovirus. sensitivity Specific spike Spike protein supply vesicular stomatitis virus VSV [DOI] 10.1016/j.talanta.2021.123147 PMC 바로가기 [Article Type] Article