Understanding lactate in the development of Hepatitis B virus-related hepatocellular carcinomaReview Published on 2024-07-152024-09-05 Journal: Infectious Agents and Cancer [Category] update2024, [키워드] Hepatitis B virus Hepatocellular carcinoma immune system Lactate [DOI] 10.1186/s13027-024-00593-4 PMC 바로가기 [Article Type] Review
Increasing Rate of Fatal Streptococcus pyogenes Bacteriemia—A Challenge for Prompt Diagnosis and Appropriate Therapy in Real PraxisArticle Published on 2024-05-152024-09-05 Journal: Microorganisms [Category] update2024, [키워드] appropriate therapy GAS bacteriaemia Lactate Myoglobin procalcitonin Streptococcus pyogenes [DOI] 10.3390/microorganisms12050995 PMC 바로가기 [Article Type] Article
Chloride and lactate as prognostic indicators of calf diarrhea from eighty-nine casesResearch Report Internal Medicine Published on 2024-05-072024-09-05 Journal: Journal of veterinary science [Category] update2024, [키워드] blood gas analysis diarrhea hematology Lactate survival rate [DOI] 10.4142/jvs.23155 PMC 바로가기 [Article Type] Research Report Internal Medicine
Targeting Mitochondrial Dynamics during Lower-Limb Ischemia Reperfusion in Young and Old Mice: Effect of Mitochondrial Fission Inhibitor-1 (mDivi-1)Article Published on 2024-04-042024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] aging ischemia reperfusion Lactate Mitochondria mitochondrial dynamics muscle Peripheral arterial disease reactive oxygen species [DOI] 10.3390/ijms25074025 PMC 바로가기 [Article Type] Article
Evaluating Mortality Predictors in COVID-19 Intensive Care Unit Patients: Insights into Age, Procalcitonin, Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Ferritin Lactate IndexArticle Published on 2024-03-242024-09-05 Journal: Diagnostics [Category] update2024, [키워드] COVID-19 ferritin Lactate Mortality neutrophil/lymphocyte ratio procalcitonin [DOI] 10.3390/diagnostics14070684 PMC 바로가기 [Article Type] Article
Can we recognize severe community-acquired pneumonia without pneumonia severity index? Use of modified qSOFA with procalcitoninResearch Article Published on 2023-09-092024-09-05 Journal: Heliyon [Category] update2024, [키워드] community-acquired pneumonia Lactate procalcitonin Scoring systems [DOI] 10.1016/j.heliyon.2023.e19937 PMC 바로가기 [Article Type] Research Article
Histone lactylation: a new epigenetic axis for host-parasite signalling in malaria?article Published on 2023-01-312024-09-01 Journal: Trends in Parasitology [Category] 말라리아, [키워드] epigenetics Hyperlactataemia Lactate lactylation malaria Plasmodium [Article Type] article
Circulating tumor necrosis factor receptors are associated with mortality and disease severity in COVID-19 patientsArticle Published on 2022-10-112022-11-15 Journal: PLoS ONE [Category] 바이오마커, [키워드] addition age Biomarker body mass index C-reactive protein Chronic kidney disease CKD conducted coronavirus disease COVID-19 COVID-19 patient COVID-19 patients CRP CRP level D-dimer demonstrated diabetes discharged disease severity enrolled enzyme-linked immunosorbent examined glomerular filtration rate Hospitalization hospitalized patient Hyperinflammatory hypertension ICU ICU patient IL-6 influence intensive care Lactate Logistic regression analysis lymphocyte counts male males median Mortality multivariate Necrosis parameters Patient patients died patients with COVID-19 Prognosis receive receptor reported Retrospective study Serum level severity Significant significantly higher the patient TNF TNFR1 TNFR2 Treatment university utility were measured White blood cells [DOI] 10.1371/journal.pone.0275745 PMC 바로가기
Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomesArticle Published on 2022-09-142022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] abundance acute phase acute respiratory syndrome Alter Analysis approach assays body mass index C-reactive protein circulating clinical decision Compromised coronavirus COVID-19 COVID-19 pathogenesis COVID-19 patient creatinine criterion Critical Critically ill cut-off value determine disease disrupt driven by dysregulation energy-related metabolites evaluated Extracellular fluorometric quantification Glucose Health Host Host immune response immune response implicated IMPROVE Increased independent predictor Infection Lactate mechanisms metabolism metabolite metabolomics mitochondrial outcome outcomes Patient Potential biomarker Prognosis Prognostic marker provided pyruvate quantification Quantitative recruited risk SARS-CoV-2 SARS-COV-2 infection semi-targeted metebolomics. serum severe COVID-19 illness severity Signaling Stratification Support validation cohort virus [DOI] 10.3389/fimmu.2022.912579 PMC 바로가기
Right dose, right now: bedside, real-time, data-driven, and personalised antibiotic dosing in critically ill patients with sepsis or septic shock-a two-centre randomised clinical trialRandomized Controlled Trial Published on 2022-09-052022-10-05 Journal: Critical Care [Category] 임상, [키워드] Acute kidney injury Adequate Adult patient antibiotic Antibiotics clinical Clinical decision support clinical trial control group COVID-19 pandemic Critically ill patient critically ill patients data-driven dose Efficacy eligible Endpoint EudraCT European evaluate faster feasibility feasible for inclusion ICU implementation IMPROVE incidence Inclusion increased mortality Infection intervention group Lactate Mortality Netherland not significantly different outcome patients personalised pharmacokinetic pharmacokinetics Primary outcome randomisation randomised Registered renal right Safe Sepsis Septic shock significantly Support Therapeutic Drug Monitoring Trial was obtained [DOI] 10.1186/s13054-022-04098-7 PMC 바로가기 [Article Type] Randomized Controlled Trial