Heterologous gam-COVID-vac (sputnik V)/mRNA-1273 (moderna) vaccination induces a stronger humoral response than homologous sputnik V in a real-world data analysisArticle Published on 2022-10-012022-11-15 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 진단, [키워드] adjusted adverse effect age Analysis Anti-spike binding antibody unit binding domain boost Combination Complete Concentration COVID COVID-19 doses enrolled evaluated event female Frequency Gam-COVID-Vac Gender Heterologous Heterologous scheme homologous humoral humoral immune response IgG immunization increase individual induce interquartile range IQR Linear model median Mild moderate Moderna mRNA-1273 mRNA-1273. participant RBD real-world data required SARS-CoV-2 Serological assay Seven significantly significantly higher vaccination Vaccine [DOI] 10.1016/j.cmi.2022.05.009 PMC 바로가기
Social connection and gene regulation during the COVID-19 pandemic: Divergent patterns for online and in-person interactionArticle Published on 2022-10-012022-11-15 Journal: Psychoneuroendocrinology [Category] 치료제, [키워드] absence analyzed antibody production antiviral immunity antiviral response association blood sample characterized connection conserved COVID-19 COVID-19 pandemic CTRA disease risk down-regulation Effect eudaimonia examined experience Factors female Gene Expression Health healthy Immune cell immune system Interaction Linear model loneliness measure Multiple offset Online social interaction profile proinflammatory gene quantified question reduced Regulation RNA Social genomics. social interaction transcriptional response [DOI] 10.1016/j.psyneuen.2022.105885 PMC 바로가기
Carbon dioxide rises beyond acceptable safety levels in children under nose and mouth covering: Results of an experimental measurement study in healthy childrenRandomized Controlled Trial Published on 2022-09-012022-10-04 Journal: Environmental research [Category] 임상, [키워드] age ambient Appropriate automated average baseline breathing breathing frequency carbon carbon dioxide children CO(2) country covariate COVID-19 determine European face Face masks Health healthy children Inhaled Linear model Mask nose not significant pandemic physiological PPM provided pulse raise Randomized Randomized study. resting position Result seated sequence significant effect Spa Standard deviation surgical variables Ventilation was measured wearing were measured [DOI] 10.1016/j.envres.2022.113564 PMC 바로가기 [Article Type] Randomized Controlled Trial
An exploratory analysis of the response to ChAdOx1 nCoV-19 (AZD1222) vaccine in males and females남성과 여성에서 ChAdOx1 nCoV-19(AZD1222) 백신에 대한 반응에 대한 탐색적 분석Article Published on 2022-07-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% CI Academy adjusted age and sex All participant All participants anti-SARS-CoV-2 anti-Spike IgG AstraZeneca AZD1222 both sexes Brazil Cellular immune response ChAdOx1 ChAdOx1 nCoV-19 Chinese clinical Clinical research clinical trials Coalition Council COVID-19 COVID-19 vaccine COVID-19 vaccines defined dose doses Efficacy endpoints Engineering enrolled Evidence evidence of Exploratory analysis fatigue female females Fever first dose Follow-up foundation funding generate GMR greater headache humoral immune responses immunogenicity immunogenicity data immunological individual Innovation interaction term ISRCTN Linear model linear models log-transformed logistic regression models majority male males Medical Science NAAT nCoV network neutralisation assay NIHR no evidence of nucleic acid nucleic acid amplification nucleic acid amplification test Oxford participant Participants primary endpoint randomised randomised controlled trial reaction reactogenicity receive Registered Regression model reported SARS-COV-2 infection Science Sex Sex-differences shown single-blind South spike IgG Standard dose statistically significant difference Superior symptomatic SARS-CoV-2 infection systemic reaction Telle the primary endpoint titre trial participants vaccination vaccination. Vaccine vaccine efficacy Vaccines Valley Volunteer [DOI] 10.1016/j.ebiom.2022.104128 PMC 바로가기 [Article Type] Article
Circulating suPAR associates with severity and in-hospital progression of COVID-19순환하는 suPAR은 COVID-19의 중증도 및 병원 내 진행과 관련이 있습니다.Observational Study Published on 2022-07-012022-09-11 Journal: European Journal of Clinical Investigation [Category] MERS, 바이오마커, 임상, [키워드] 95% CI Accuracy Admission Adult patients age albumin assays association AUC best characterized clinical correlated COVID-19 COVID-19 disease CRP discrimination Disease progression disease severity doubling EGFR ELISA females ferritin FIVE Hospital admission hyperinflammation IMPROVE In-hospital interleukin interleukin-6 International Lactate lactate dehydrogenase LDH Linear model male marker median age observational study outcome parameter patients patients hospitalized plasma suPAR predict primary outcome measure procalcitonin progression risk stratification scale serum albumin serum lactate severity severity of COVID-19 significantly significantly lower suPAR suPAR. survival survivor Treatment WHO WHO Clinical Progression Scale WHO-CPS [DOI] 10.1111/eci.13794 PMC 바로가기 [Article Type] Observational Study
Insights to estimate exposure to regulated and non-regulated disinfection by-products in drinking water Research Published on 2022-06-292022-10-05 Journal: Journal of Exposure Science & Environmental Epidemiology [Category] 바이오마커, [키워드] activated Activated carbon analyzed Barcelona Chlorate collected Concentration concentrations correlated DBP Effect epidemiological studies explained filtered finding Health Impact information insight Linear model Linear regression Linear regression model machine learning models median multivariate number of sample objective Occurrence participant predict Predictive Predictive model quantified Questionnaires reduced regulated Replication Result Significance Spain study population tap THM total variance Urine validation variable [DOI] 10.1038/s41370-022-00453-6 [Article Type] Research
Nursing Workflow Change in a COVID-19 Inpatient Unit Following the Deployment of Inpatient Telehealth: Observational Study Using a Real-Time Locating SystemObservational Study Published on 2022-06-172022-10-05 Journal: Journal of Medical Internet Research [Category] 임상, [키워드] adopted association averaged baseline calculated Care causal link change changes in complement COVID-19 COVID-19 pandemic determine disease transmission downstream evaluate event Frequency Generalized greater Health health care professional health care staff Health risk Impact implementation implication informatics Inpatient limitation Linear model maintain not differ Nurse Nurses Nursing observation period outcome pandemic pathogen pathogen exposure Patient patient outcomes patient safety Personal protective equipment platform PPE real-time locating system reduce remained reported Stage System telehealth Telemedicine understanding unit Virtual care virtual care. widespread [DOI] 10.2196/36882 PMC 바로가기 [Article Type] Observational Study
Beyond GWAS-Could Genetic Differentiation within the Allograft Rejection Pathway Shape Natural Immunity to COVID-19?GWAS를 넘어 동종이식 거부 경로 내 유전적 분화가 COVID-19에 대한 자연 면역을 형성할 수 있습니까?Article Published on 2022-06-032022-09-11 Journal: International Journal of Molecular Sciences [Category] 변종, [키워드] Allograft allograft rejection Analysis annotation antiviral immunity applied Biomarker Biomarkers chromosome chromosome 6 chromosomes clinical presentation component components COVID-19 COVID-19 infection COVID-19 infections cumulative demonstrated differentiation disease Factor Genetic genetic variants genetics Genome-wide association study genomic GWAS Health help hospitalisation Host identify immune response immune responses immune system immunisation Infection investigated KEGG KEGG pathways Linear model majority mapped metabolic pathway metabolic pathways natural nucleotide outcome pathway Pathways Patient rejection resistance risk Risk assessment self Sequencing severe COVID-19 Severe COVID-19 Infection shape single nucleotide Single nucleotide polymorphism single variant SNP SNPs susceptibility Treatment variant whole genome Whole genome sequencing whole genome sequencing. [DOI] 10.3390/ijms23116272 PMC 바로가기 [Article Type] Article
Humoral response to SARS-CoV-2 vaccines in people living with HIVHIV 감염자의 SARS-CoV-2 백신에 대한 체액 반응Article Published on 2022-06-012022-09-12 Journal: Infection [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] adjusted Analysis anti-SARS-CoV-2 antibody anti-SARS-CoV-2-antibody antibody antibody concentration Antibody Response association CD4 CD4 cell comparative statistics Concentration concentrations COVID-19 COVID-19 vaccine COVID-19 vaccines cumulative electronic patient file Factor female Generalized Germany HIV humoral immune response Humoral response identify IQR Linear model logit magnitude males median mRNA vaccine Munich PLWH quartiles robust SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2. significantly subjects threshold vaccination variable were used with HIV [DOI] 10.1007/s15010-021-01721-7 PMC 바로가기 [Article Type] Article
Cancer incidence and mortality in Australia from 2020 to 2044 and an exploratory analysis of the potential effect of treatment delays during the COVID-19 pandemic: a statistical modelling study2020년부터 2044년까지 호주의 암 발병률 및 사망률과 COVID-19 전염병 동안 치료 지연의 잠재적 영향에 대한 탐색적 분석: 통계적 모델링 연구Article Published on 2022-06-012022-09-12 Journal: The Lancet. Public Health [Category] Fulltext, MERS, 진단, 치료법, [키워드] absence alcohol Antigen baseline Breast cancer Cancer cancer treatment cancer type Care cigarette smoking Colorectal cancer Council COVID-19 COVID-19 pandemic death effect of treatment Effects effort example expected Exploratory analysis female females growth Health Service health-care system hypothetical incidence incidence rate incidence rates increase in infections Linear model male males management Mortality mortality rate mortality rates number obesity Patient Physical inactivity Prevalence projection public health resources risk Risk factors risk of death smoking statistical survival systematic review Treatment was selected [DOI] 10.1016/S2468-2667(22)00090-1 PMC 바로가기 [Article Type] Article