lipid-lowering drugs
[대역어] 지질 저하 약물
[용어속성] Term
[용어속성] Term
Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study
멘델식 무작위 배정 연구에서 지질 저하 약물과 COVID-19 결과의 연관성
Research Article
[키워드] 95% CI
95% confidence interval
Analysis
approach
association
associations
benefit
Blood
calculate
carried
causal relationship
caused
cholesterol
clinical trial
confounding bias
COVID-19
COVID-19 hospitalization
COVID-19 pandemic
death
decrease
drug
drugs
eLife
estimates
Evidence
expression
expression quantitative trait loci
faster
fat
funding
genetic instrument
genetic instruments
Genetic variant
genetic variants
Genome-wide association study
higher risk
HMGCR
Hospitalization
Hospitalized
Human
Hypothesis
identify
in viral
infected with SARS-CoV-2
Infection
infections
LDL cholesterol
Lipid
lipid metabolism
lipid-lowering drugs
loci
low-density
Low-density lipoprotein
mendelian randomization
Mendelian randomization studies
Mendelian randomization study
metabolism
Mortality
MR study
NPC1L1
Odds ratio
outcome
Patient
PCSK9
positive
protective effect
Quantitative
reduce
reduced risk
SARS-CoV-2
SARS-COV-2 infection
severe disease
SMR
statins
suggested
susceptibility
target gene
Target genes
treating COVID-19
university
variable
Viral
viral infections
virus
were used
with COVID-19
[DOI] 10.7554/eLife.73873 PMC 바로가기 [Article Type] Research Article
[DOI] 10.7554/eLife.73873 PMC 바로가기 [Article Type] Research Article
Possible mechanisms of cholesterol elevation aggravating COVID-19
COVID-19를 악화시키는 콜레스테롤 상승의 가능한 메커니즘
Review
[키워드] ACE2
activating
angiotensin
Angiotensin-converting enzyme
angiotensin-converting enzyme 2
anti-inflammatory effect
antiviral drugs
Atherosclerosis
atherosclerotic
atherosclerotic plaques
Blood
cell entry
cells
cholesterol
contribute
coronavirus disease
Coronavirus disease 2019
COVID-19
COVID-19 infection
Deterioration
domain
drugs
fusion protein
host cell
host cell membrane
host cells
Human
In vitro studies
Infection
Inflammatory
interact
LDL-C
lipid-lowering drugs
mechanism
membrane
membrane fusion
NLR
NLR family pyrin domain containing 3
NLRP3
observations
Patient
patients with COVID-19
Previous studies
previous study
Prognosis
promote
protective effect
receptor
Research
respiratory
resulting
risk of death
SARS-CoV-2
scavenger receptor
Severe acute respiratory syndrome
shown
Spike protein
subsequent
susceptibility
the spike protein
therapy
Treatment
Vaccine
Viral
viral entry
virus
with COVID-19
[DOI] 10.7150/ijms.62021 PMC 바로가기 [Article Type] Review
[DOI] 10.7150/ijms.62021 PMC 바로가기 [Article Type] Review