Lipid rafts disruption by statins negatively impacts the interaction between SARS-CoV-2 S1 subunit and ACE2 in intestinal epithelial cellsMicrobiology Original Research Published on 2024-01-082024-09-05 Journal: Frontiers in Microbiology [Category] update2024, [키워드] Lipid rafts protein trafficking Protein–protein interaction SARS-CoV-2 statins [DOI] 10.3389/fmicb.2023.1335458 PMC 바로가기 [Article Type] Microbiology Original Research
The Function behind the Relation between Lipid Metabolism and Vimentin on H9N2 Subtype AIV ReplicationArticle Published on 2022-08-182023-06-22 Journal: Viruses [Category] 조류인플루엔자, [키워드] AMPK cholesterol H9N2 subtype AIV HMGCR Lipid rafts vimentin [DOI] 10.3390/v14081814 PMC 바로가기
SARS-CoV-2 Infection-Of Music and Mechanics of Its Spikes! A PerspectiveArticle Published on 2022-05-242022-11-15 Journal: ACS Nano [Category] COVID19(2023년), SARS, 치료제, [키워드] ACE2 arising Biochemistry cellular Cobicistat coronavirus COVID-19 COVID-19 pandemic D614G darunavir Disulfide dorian Egmont endocytosis GSH GSSG hydrogen bonds Lipid rafts Lopinavir manifestation Mechanics mechanobiology music Pandemics peptide piezoelectricity produced Remdesivir Research Ritonavir SARS-CoV-2 spikes the SARS-CoV-2 virus Vaccine Vaccines virus virus propagation while [DOI] 10.1021/acsnano.1c11491 PMC 바로가기
Lipid rafts as viral entry routes and immune platforms: A double-edged sword in SARS-CoV-2 infection?Review Published on 2022-03-042023-07-01 Journal: Biochimica et biophysica acta. Molecular and cell [Category] COVID19(2023년), SARS, [키워드] anticoagulant drugs antiviral drugs COVID-19 immunosuppressive drugs Lipid rafts lipid-lowering drugs monoclonal antibodies SARS-CoV-2 [DOI] 10.1016/j.bbalip.2022.159140 PMC 바로가기 [Article Type] Review
Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid RaftsImmunology Published on 2022-02-182022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] ACE2 affected Calu-3 cell caused cell entry cell membrane Clinical studies coronavirus 2 Coronavirus disease 2019 Course COVID-19 dependent on Disruption downregulated exhibit experimental evidence hospitalized patient human neutrophils in vitro in vivo Infection Inflammation inflammatory cytokine production Inflammatory response inhibiting Lipid Lipid rafts lung damage lung epithelial mechanism mice modulate Monocytes Mortality Peripheral blood protective effect raft reduced reported respiratory response SARS-CoV-2 SARS-COV-2 infection significantly Simvastatin statin systemically tissue Treatment triggered viral replication virus with COVID-19 [DOI] 10.3389/fimmu.2022.820131 PMC 바로가기 [Article Type] Immunology
Editorial: Role of Lipid Rafts in Anti-microbial Immune ResponseImmunology Published on 2021-02-262022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] immune response Infection Lipid Lipid rafts microbial phagocytosis pathogen recognition receptors raft response role [DOI] 10.3389/fimmu.2021.654776 PMC 바로가기 [Article Type] Immunology
Targeting Lipid Rafts as a Strategy Against CoronavirusCell and Developmental Biology Published on 2021-02-042022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] ACE-2 ACE-2 receptor acute respiratory syndrome Affect affecting Against Alpha angiotensin-converting enzyme-2 Antiviral compounds approach autophagic bind binding Bioavailability characterized cholesterol clearance complexes component coronavirus Coronavirus-2 Coronaviruses cyclodextrins domain downstream drug functional host cell host cell membrane host cell surface impairing Inclusion involved Lipid Lipid rafts main receptor membrane N-terminal Necrosis pharmacological platform proinflammatory molecule raft reducing Region Remdesivir SARS-CoV-2 selective sialic acid sphingolipids Spike protein statins Strategy targeting the SARS-CoV-2 the spike protein these compound TNF-α viral envelope viral replication virus infectivity viruses [DOI] 10.3389/fcell.2020.618296 PMC 바로가기 [Article Type] Cell and Developmental Biology
Cholesterol, inflammation, and phospholipids: COVID-19 share traits with cardiovascular disease콜레스테롤, 염증 및 인지질: COVID-19는 심혈관 질환과 특성을 공유합니다Article Published on 2021-01-012022-09-11 Journal: Biochimica et biophysica acta. Molecular and cell [Category] MERS, SARS, 바이오마커, [키워드] Abstract Antiphospholipid syndrome cardiovascular disease cholesterol COVID-19 fatty Inflammation LDL Lipid Lipid rafts Omega Omega 3 fatty acids Phospholipids S1P. [DOI] 10.1016/j.bbalip.2020.158839 PMC 바로가기 [Article Type] Article
Stochastic models for objects and images in oncology and virology: application to PI3K-Akt-mTOR signaling and COVID-19 diseaseBiomedical Applications in Molecular, Structural, and Functional Imaging Published on 2020-11-262022-10-30 Journal: Journal of Medical Imaging [Category] COVID-19, [키워드] Algorithm calculated Cancer characteristic characteristic functional Computerized tomography continuous variable coronavirus COVID COVID-19 COVID-19 disease develop disease disrupt effort function functional Lipid rafts mammalian mammalian target of rapamycin signaling mathematical molecular multidimensional oncology Patient physiological Probability problem random Rapamycin Research Signaling signaling pathway stochastic stochastic models university [DOI] 10.1117/1.JMI.8.S1.S16001 PMC 바로가기 [Article Type] Biomedical Applications in Molecular, Structural, and Functional Imaging
Targeting Lipid Rafts—A Potential Therapy for COVID-19Immunology Published on 2020-09-292022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, [키워드] Activation acute infection acute phase Anti-viral approach attributes binding change characteristic cholesterol chronic disease co-morbidity Community coronavirus COVID-19 COVID-19 infection dysregulation effective global pandemic Health Host immune Infection Inflammation inflammatory disorders Inflammatory responses initial lifecycle Lipid Lipid rafts lipids local outbreak medication Modification Mutagenesis phenotype Potential problems public health measure rapid expansion reducing Safe SARS-CoV-2 Stage target targeting Therapeutic approach therapy transmission of SARS-CoV-2 Treatment viral infection virus while [DOI] 10.3389/fimmu.2020.574508 PMC 바로가기 [Article Type] Immunology