Removal performance of SARS-CoV-2 in wastewater treatment by membrane bioreactor, anaerobic-anoxic-oxic, and conventional activated sludge processesArticle Published on 2022-12-102022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] activated applicability CAS chlorination collected COVID-19 outbreak Detection limit evaluate Final fraction independent influent investigated Japan log Log reduction Log reduction value (LRV) lowest membrane Membrane bioreactor (MBR) Mild Pepper mild mottle virus (PMMoV) potential risk quantified reduction removal RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA significantly lower treated Treatment virus wastewater Wastewater treatment plant (WWTP). [DOI] 10.1016/j.scitotenv.2022.158310 PMC 바로가기
Building-level wastewater surveillance of SARS-CoV-2 is associated with transmission and variant trends in a university settingArticle Published on 2022-12-012022-11-16 Journal: Environmental research [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant analyzed associations Building-level surveillance Clinical data clinical testing collected complement Concentration contributed COVID-19 COVID-19 case creating Epidemiology genetic mutation hotspot identify include indicate Intervention Isolation less log N1 and N2 Nucleocapsid gene positive positive control quantification quarantine repeated reported Research SARS-CoV-2 SARS-CoV-2 RNA second wave South spring statistical significance statistically significant Surveillance Transmission university variant variants of concern Viral RNA Viral transmission VOCs Wastewater-based epidemiology. [DOI] 10.1016/j.envres.2022.114277 PMC 바로가기
SARS-CoV-2 RNA load in nasopharyngeal specimens from outpatients with breakthrough COVID-19 due to Omicron BA.1 and BA.2Article Published on 2022-12-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome All participant BA.1 BA.2 Booster vaccine caused collected comparable composed coronavirus coronavirus disease COVID-19 Day Diagnosis dose elapsed had no Infection log median median age nasopharyngeal specimen omicron Omicron variant Outpatient Patient reached retrospective RNA SARS-CoV-2 SARS-CoV-2 RNA Support symptom onset TaqPath Thermo Fisher Scientific time Transmissibility upper respiratory tract URT vaccination schedule Vaccine vaccine dose Viral load Viral load. viral RNA load was used [DOI] 10.1002/jmv.28079 PMC 바로가기
Development of a magnetic nanoparticle-based method for concentrating SARS-CoV-2 in wastewaterArticle Published on 2022-11-202022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome affected applicability applied comparable Concentration coronavirus detect Detection sensitivity development Epidemiology limitations log magnetic nanoparticle Mild MNP Modification MS2 Pegcision Polyethylene glycol Polyethylene glycol precipitation polymerase chain Pseudomona quantified reducing SARS-CoV-2 SARS-CoV-2 RNA sensitivity virus virus virus concentration viruses Wastewater-based epidemiology. [DOI] 10.1016/j.scitotenv.2022.157613 PMC 바로가기
Severe immunosuppression is related to poorer immunogenicity to SARS-CoV-2 vaccines among people living with HIVArticle Published on 2022-11-012022-11-15 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI Analysis Antibody Response CD4 CD4 cell CD4 count CD4 T-cell CD4 T-cell counts Cluster Complete COVID-19 vaccine COVID-19 vaccines determine dose evaluated Humoral response IgG IgG antibody immunization Immunosuppression impair individual log median mRNA multicentre neutralization Neutralizing antibodies Patient people living with HIV PLWH predictor Probability prospective cohort study quantitative determination receiving response to vaccination SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines Seroconversion Specific the antibody response the vaccine vaccination Vaccine vaccine. with HIV [DOI] 10.1016/j.cmi.2022.05.018 PMC 바로가기
A Randomized Phase 2/3 Study of Ensitrelvir, a Novel Oral SARS-CoV-2 3C-Like Protease Inhibitor, in Japanese Patients with Mild-to-Moderate COVID-19 or Asymptomatic SARS-CoV-2 Infection: Results of the Phase 2a PartArticle Published on 2022-10-182022-11-15 Journal: Antimicrobial Agents and Chemotherapy [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome All adverse event Asymptomatic baseline clinical coronavirus coronavirus disease COVID-19 Culture demonstrated double-blind Efficacy and safety ensitrelvir fumaric acid greater group groups intention-to-treat population Japan Japanese log median time Mild Mild-to-moderate moderate multicenter novel oral Part Patient phase phase 2/3 Placebo positive Primary outcome proof-of-concept study protease Protease inhibitor Randomized receive reduced registry Result S-217622 SARS-CoV-2 SARS-CoV-2 3C-like protease inhibitor SARS-CoV-2 clearance SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 viral the SARS-CoV-2 tissue Treatment viral clearance Viral RNA viral titer viral titer. [DOI] 10.1128/aac.00697-22 PMC 바로가기
Antiviral effect of multipurpose contact lens disinfecting solutions against coronavirusArticle Published on 2022-10-012022-11-15 Journal: Contact lens & anterior eye : the journal of the British Contact Lens [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Ammonium Antiviral antiviral activity Concentration conducted Contact Contact len Contact lens disinfection coronavirus coronavirus Detection limit evaluate Final FIVE hydrogen hydrogen peroxide incubated Iodine kill log mouse hepatitis virus negative control oxidative PBS phosphate buffer plaque forming unit quantified Quaternary ammonium. reduced reduction regimen SARS-CoV-2 significantly temperature Test treated Treatment virus virus [DOI] 10.1016/j.clae.2021.101513 PMC 바로가기
An electrochemical aptasensor with N protein binding aptamer-complementary oligonucleotide as probe for ultra-sensitive detection of COVID-19N 단백질 결합 앱타머-상보성 올리고뉴클레오티드를 COVID-19의 초고감도 검출을 위한 프로브로 사용하는 전기화학적 앱타센서Article Published on 2022-10-012022-09-11 Journal: Biosensors & bioelectronics [Category] 치료기술, 치료제, [키워드] affected applied aptamer binding blood sample Blood samples changes in complementary Complementary DNA Concentration conformational COVID-19 COVID-19 epidemic COVID-19 in patients DNA double-stranded Early detection effective Electrochemical aptasensor gold hybridization Incubation linear relationship log logarithm N protein N protein detection probe R 2 Rapid Rapid COVID-19 diagnosis Regenerable aptamer sensor. reported sensor solution target the N protein throat swab throat swabs vaccination volunteers was measured [DOI] 10.1016/j.bios.2022.114436 PMC 바로가기 [Article Type] Article
Performance of nasopharyngeal swab and saliva in detecting Delta and Omicron SARS-CoV-2 variantsDelta 및 Omicron SARS-CoV-2 변이체 검출 시 비인두 면봉 및 타액의 성능Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analyzed Chain Reaction characterized conducted coronavirus cough COVID-19 Delta diagnostic Dyspnea epidemic wave epidemic waves expressed highest increase in Infection Laboratory log molecular nasopharyngeal Nasopharyngeal swab no significant difference not significant NP swab NP swabs NPs nucleic acids omicron participant Participants Patient performance polymerase chain polymerase chain reaction processing prospective cohort study real-time RT-PCR reported required respiratory rhinorrhea RNA Saliva saliva samples Saliva. Sample SARS-CoV-2 SARS-CoV-2 diagnostics SARS-CoV-2 epidemic SARS-CoV-2 variant significant difference sore sore throat specimen specimen collection statistically Symptom Symptoms thawing the mean transported Viral Viral load [DOI] 10.1002/jmv.27898 PMC 바로가기 [Article Type] Article
SARS-CoV-2 spike protein antibody titers 6 months after SARS-CoV-2 mRNA vaccination among patients undergoing hemodialysis in JapanArticle Published on 2022-10-012022-11-15 Journal: Clinical and experimental nephrology [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome anti-SARS-CoV-2 spike protein antibody Antibody titer Antibody titers BNT162b2 calculated clinics conducted contributed controls coronavirus death dose FIVE HD group healthy control Hemodialysis immune response Japan linear log log-transformed Lower mixed-effects model mRNA vaccination mRNA vaccine Patient patients Pfizer-BioNTech Prevent Protein reduced remained Retrospective study S1 IgG SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike protein second dose second vaccination shown significantly significantly lower vaccination Vaccine vaccine. were measured [DOI] 10.1007/s10157-022-02243-8 PMC 바로가기