Demographic and clinical characteristics of pediatric COVID-19 in Arkansas: March-December 2020Article Published on 2022-10-212022-11-16 Journal: Medicine [Category] 변종, [키워드] acute COVID-19 Admission Adolescent Adults children Clinical characteristics clinically Community country COVID COVID-19 COVID-19 pandemic demographic determine discharge evaluate Fever gastrointestinal symptoms hospital hospitals Inflammatory LOS lower mortality MIS-C morbidity Older Patient pediatric positive presenting presenting symptom proportion reached resource Retrospective study Spread study population syndrome tested the United State Transport upper respiratory symptoms Vaccinations variant with COVID-19 [DOI] 10.1097/MD.0000000000031058 PMC 바로가기
An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patientsArticle Published on 2022-10-052022-11-16 Journal: eLife [Category] COVID19(2023년), SARS, 변종, [키워드] adjusted Analysis Appendix approach assumption available data Calabria carrier caused changes in characterisation clinical Clinical outcome Clinical research clinical study collected Commonwealth confidence interval confounders COVID-19 dataset DAVID development Donor emergence Epidemiology European European Commission fatality Foreign foundation Frequency funding global health Google.org group heterogeneity Horizon hospital hospitalised hospitalised patient Imperial College London include infecting Infection Infectious disease International IRCCS ISARIC Italian Joshua less Logistic regression lower mortality Medical Research Council Medicine Melinda Gate Microbiology Ministry of Health network NIHR NIHR HPRU Odds ratio office omicron opportunity outcome Oxford Patient PHE protection Public Health England Rapid relative frequencies reported symptom Research respiratory response responsible Rockefeller Foundation SARS-CoV-2 variant School Semple sensitivity analysis Sriniva study population subset Support supported Symptoms union unit University of Liverpool University of Oxford variant variants viral genomic information viruses with COVID-19 [DOI] 10.7554/eLife.80556 PMC 바로가기
Management of Cerebral Venous Thrombosis Due to Adenoviral COVID-19 VaccinationArticle Published on 2022-10-012022-11-15 Journal: Annals of neurology [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI 95% confidence interval adenovirus-based adjusted adjusted odds ratio administration adverse effect analyzed ANN Anticoagulant Anticoagulants association autoimmune pathogenesis avoidance caused cerebral country COVID-19 diagnosed evaluate had no heparin hospital immune immunomodulation International Intravenous immunoglobulin lower mortality Mortality Patient Platelet recommendation reducing mortality SARS-CoV-2 SARS-CoV-2 vaccination significantly statistically significant the patient thrombotic treated Treatment used data Vaccines Venous thrombosis [DOI] 10.1002/ana.26431 PMC 바로가기
Real-life Evidence of Lower Lung Virulence in COVID-19 Inpatients Infected with SARS-CoV-2 Omicron Variant Compared to Wild-Type and Delta SARS-CoV-2 PneumoniaArticle Published on 2022-10-012022-11-16 Journal: Lung [Category] COVID19(2023년), SARS, 변종, [키워드] adult subject ambient animal model ARDS better respiratory function blood gas analysis Comorbidities consolidation COVID-19 Delta described evidence of explain hospital Hospitalization Immunity in vitro Infection Inpatient Italy less Lineage Lower lower mortality lower risk lung parenchyma observation omicron other variant Pneumonia preliminary finding replication capacity respiratory airway Respiratory failure SARS-CoV-2 severe respiratory failure Turin variants of concern virulence wild type [DOI] 10.1007/s00408-022-00566-7 PMC 바로가기
Mortality Risk Among Patients Hospitalized Primarily for COVID-19 During the Omicron and Delta Variant Pandemic Periods – United States, April 2020-June 2022Article Published on 2022-09-162022-11-16 Journal: Morbidity and Mortality Weekly Report [Category] SARS, 변종, [키워드] adjusted age calculated cause CDC Clinical characteristics COVID-19 COVID-19 hospitalization database deaths Delta early treatment Ethnic groups females Health authority hospital hospitalized COVID-19 patient hospitalized patients In-hospital death in-hospital mortality increase indicated lower mortality male medical condition Medical conditions Mortality mortality risk nonpharmaceutical intervention occurred omicron pandemic Patient patients hospitalized Period proportion public health Racial reported risk United States variant variant of SARS-CoV-2 virus [DOI] 10.15585/mmwr.mm7137a4 PMC 바로가기
Evaluating the Performance of Centers for Disease Control and Prevention COVID-19 Community Levels as Leading Indicators of COVID-19 MortalityArticle Published on 2022-09-012022-11-16 Journal: Annals of internal medicine [Category] Fulltext, MERS, 변종, [키워드] Analysis CDC center Community complicate Control Council COVID-19 death diagnostic elevated evaluate Evaluating Evolution exceeded Hospital admission Hospital admissions hospitalizations Immunity IMPROVE Indicator interquartile range IQR leading Level lower mortality median medium Metrics Mortality mortality rate mortality risk National Negative predictive value outcome performance Positive predictive value Predictive predictor prevention public health Ratio reported risk sensitivity specificity state Support Surveillance threshold time Viral variants [DOI] 10.7326/M22-0803 PMC 바로가기
Efficacy of pharmacological interventions in COVID-19: A network meta-analysisCovid-19의 약리학 적 개입의 효능 : 네트워크 메타 분석Meta-Analysis Published on 2022-09-012022-09-08 Journal: British Journal of Clinical Pharmacology [Category] meta-analysis, 임상, 치료제, [키워드] 95% confidence interval Administered analysed Clinical improvement clinical recovery Controlled trial coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 database Dexamethasone drug Favipiravir followed by head Head-to-head comparison Hydroxychloroquine increase interferon Intervention investigator Lopinavir Lopinavir/ritonavir lower mortality lower risk lower risk of mortality MeSH term moderate to severe Mortality Network meta-analysis Occurrence patients with moderate pharmacological intervention Quantitative analysis Randomized controlled trial reduce reduced Relative risk Remdesivir risk Ritonavir screened Serious Adverse Event Serious Adverse Events severe COVID-19 significantly Standard of care Tocilizumab was performed [DOI] 10.1111/bcp.15338 PMC 바로가기 [Article Type] Meta-Analysis
An alternative to airborne droplet transmission route of SARS-CoV-2, the feco-oral route, as a factor shaping COVID-19 pandemicResearch article Published on 2022-09-012022-10-05 Journal: Medical Hypotheses [Category] 변종, [키워드] Chinese Contact country Course COVID-19 COVID-19 pandemic COVID-19 severity demonstrated dominant droplet transmission feco-oral transmission Frequency Gastrointestinal routes of infection gastrointestinal symptoms gastrointestinal tract help herd immunity Hypothesis Immunity Inflammatory response less long-lasting lower mortality Mild pandemic Pandemics population immunity producing Prognosis rapid increase resulting route of infection SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection SARS-CoV-2 transmission severity Spread swabs traditional method Viral antigen virus attenuation [DOI] 10.1016/j.mehy.2022.110903 [Article Type] Research article
Timing and Outcomes of Noninvasive Ventilation in 307 ARDS COVID-19 Patients: An Observational Study in an Italian Third Level COVID-19 HospitalObservational Study Published on 2022-08-152022-10-05 Journal: Medicina [Category] 임상, [키워드] 95% CI acute respiratory distress acute respiratory distress syndrome adjusted odds ratio analyzed appear ARDS ARDS COVID-19 patient conducted Coronavirus disease 2019 correlated COVID-19 COVID-19 pandemic COVID-19 patient death defined Effectiveness Efficacy etiologies Evidence Factor hospital Hospital wards Hospitalization ICU ICU admission increased risk independent intensive care intensive care unit intubated COVID-19 patient intubation Italian Italy lack Level Logistic regression analysis lower mortality material Mild moderate Mortality NIV NIV failure noninvasive Noninvasive ventilation objective Observational cohort study occurred Occurrence orotracheal intubation. outcome P/F Patient patients patients with ARDS patients with COVID-19 reduce respiratory Result risk risk of death Rome severe ARDS severity significantly study period Support treated Treatment Ventilation [DOI] 10.3390/medicina58081104 PMC 바로가기 [Article Type] Observational Study
Should RECOVERY have used response adaptive randomisation? Evidence from a simulation studyRandomized Controlled Trial Published on 2022-08-062022-10-04 Journal: BMC Medical Research Methodology [Category] SARS, 임상, [키워드] adaptive adaptive randomisation Adaptive trial Arm ARMS Care Community coronavirus COVID-19 COVID-19 mortality COVID-19 therapy defined Dexamethasone effective error rate estimate exhibiting FIVE fixed form hospitalised Hydroxychloroquine induce Lopinavir-ritonavir lower mortality Measures mortality rate other diseases Patient patient death patient subgroup performed Platform trial question randomisation randomised controlled trial Randomised Evaluation receiving recovery RECOVERY trial reduced reducing reduction REMAP-CAP representing Respiratory Support Response-adaptive randomization Simulation standard care Statistical power tested Treatment Trial Two-arm [DOI] 10.1186/s12874-022-01691-w PMC 바로가기 [Article Type] Randomized Controlled Trial