The impact of shifting demographics, variants of concern and vaccination on outcomes during the first 3 COVID-19 waves in Alberta and Ontario: a retrospective cohort study알버타와 온타리오에서 처음 3번의 COVID-19 파동 동안 인구 통계학적 변화, 우려의 변형 및 백신 접종이 결과에 미치는 영향: 후향적 코호트 연구Article Published on 2022-04-262022-09-11 Journal: CMAJ open [Category] COVID19(2023년), SARS, 변종, [키워드] 30-Day mortality 95% CI 95% confidence interval adjusted odds ratio age all-cause hospitalization Alpha Alpha variant anticipated Canada Care Chain Reaction changes in Charlson Comorbidity Index Comorbidities Comorbidity conducted COVID-19 data set death delta variant demographics disease expression examined genomic Health Health care Health care system higher risk Hospital stay Hospitalization Hospitalized individual infected with SARS-CoV-2 Infection lower mortality risk median outcome pandemic Patient phenotype Phenotypes polymerase chain polymerase chain reaction positive result retrospective cohort study reverse transcription SARS-CoV-2 SARS-COV-2 infection Sex shift shifting vaccination Vaccination Status variant variants variants of concern Wave Waves were infected wild-type SARS-CoV-2 younger patient younger patients [DOI] 10.9778/cmajo.20210323 PMC 바로가기 [Article Type] Article
Antiplatelet therapy and outcome in COVID-19: the Health Outcome Predictive Evaluation RegistryObservational Study Published on 2022-01-012022-10-04 Journal: Heart (British Cardiac Society) [Category] 임상, [키워드] 95% CI anticoagulation antiplatelet Aspirin bleeding clinical consecutive patient COVID-19 diabete drugs Efficacy embolic enrolled evaluate event hospitalisation hospitalised patient In-hospital in-hospital complication in-hospital mortality increased risk International invasive ventilation lower mortality lower mortality risk male mechanical ventilation microthrombi multicentre multivariable analysis no difference Older organs outcome Patient Pharmacology Prevalence registry risk Standard survival therapy therapy for COVID-19 treated were recorded with COVID-19 [DOI] 10.1136/heartjnl-2021-319552 PMC 바로가기 [Article Type] Observational Study
Mortality Risk Among Patients With COVID-19 Prescribed Selective Serotonin Reuptake Inhibitor AntidepressantsResearch Published on 2021-11-152022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, SARS, [키워드] adjusted age antidepressant association Care cohort study Comorbidities control patient control patients COVID-19 database decreased mortality defined demographic characteristics diagnosed with COVID-19 duration of follow-up EHR Electronic health record Evidence exposure finding Frame Health Importance involved lower mortality risk measure medication Mortality multicenter cohort study objective outcome outcomes participant Patient patients with COVID-19 Point Proinflammatory cytokine propensity score matching randomized clinical trial receiving reduce mortality reduced reduction in reflected Relevance reported representing Research Result retrospective cohort study Reuptake risk risk of death RR of mortality selective serotonin reuptake inhibitor setting severe COVID-19 severity of COVID-19 statistically significant subject suggested Support treated was reduced women [DOI] 10.1001/jamanetworkopen.2021.33090 PMC 바로가기 [Article Type] Research
Association between serum retinol and overall and cause-specific mortality in a 30-year prospective cohort studyArticle Published on 2021-11-052022-10-04 Journal: Nature Communications [Category] 바이오마커, [키워드] alcohol Analysis association beta-carotene body mass index cardiovascular diseases cause-specific mortality circulation Cohort Concentration concentrations CVD death Diabetes Mellitus disease Effect Epidemiology Follow-up follow-up time Health indicated intensity lower mortality risk lower risk lowest mediation men Mortality Nutrition disorders overall mortality participant prospective cohort study Respiratory disease respiratory diseases retinol risk serum significantly lower smoking subgroup Trial Vitamin vitamin A [DOI] 10.1038/s41467-021-26639-4 PMC 바로가기 [Article Type] Article
Hydroxychloroquine and mortality in COVID-19 patients: a systematic review and a meta-analysis of observational studies and randomized controlled trialsCOVID-19 환자의 하이드록시클로로퀸과 사망률: 관찰 연구 및 무작위 대조 시험에 대한 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-10-012022-09-11 Journal: Pathogens and global health [Category] SARS, 임상, 치료제, [키워드] article association Azithromycin certainty certainty of evidence clinical trials Cohort studies cohort study COVID-19 COVID-19 patient COVID-19 patients debate Evidence evidence of HCQ help Hydroxychloroquine lower dose lower mortality risk Meta-analysis Mortality observational studies observational study patients Potential treatment randomized clinical trial Randomized controlled trial RCT RCTs reduction retrieved risk risk ratio SARS-CoV-2 Seven severe adverse event severe adverse events systematic review total mortality were used [DOI] 10.1080/20477724.2021.1936818 PMC 바로가기 [Article Type] Meta-Analysis
Mortality Risk of Antidiabetic Agents for Type 2 Diabetes With COVID-19: A Systematic Review and Meta-AnalysisEndocrinology Published on 2021-09-162022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, [키워드] 95% CI agent antidiabetic antidiabetic agents association Cochrane Library conducted coronavirus disease COVID-19 database diabetes Effect exhibited greater inhibitor insulin lower mortality risk Meta-analysis metformin Mortality mortality risk outcome Patient performed reduced Registration Result review significantly systematic review Type type 2 diabete type 2 diabetes Web of Science were used [DOI] 10.3389/fendo.2021.708494 PMC 바로가기 [Article Type] Endocrinology
COVID-19-Associated Mortality in US Veterans with and without SARS-CoV-2 InfectionArticle Published on 2021-08-112022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] 30-Day mortality Affect age alcohol Analysis analyzed BMI Cohort cohort analysis confounders coronavirus disease COVID-19 decreased mortality disorder evaluated increased mortality infected patient lower mortality risk male men Mortality mortality risk performed reduced risk risk factor SARS-CoV-2 smoking smoking status subject subjects tested uninfected veteran while yielding [DOI] 10.3390/ijerph18168486 PMC 바로가기 [Article Type] Article
Effect of Anticoagulant Administration on the Mortality of Hospitalized Patients With COVID-19: An Updated Systematic Review and Meta-AnalysisMedicine Published on 2021-08-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval administration Anticoagulant anticoagulant therapy anticoagulation assessment benefit bleeding bleeding event bleeding events coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critically ill decreased mortality development Effect Evidence heparin hospital hospitalized COVID-19 patient hospitalized patient incidence Inconclusive intensive care unit lower mortality risk Meta-analysis Mortality observational study patients with COVID-19 random-effects model review risk systematic review therapy Thromboprophylaxis Trial variable was used with COVID-19 [DOI] 10.3389/fmed.2021.698935 PMC 바로가기 [Article Type] Medicine
Mental disorders, psychopharmacological treatments, and mortality in 2150 COVID-19 Spanish inpatients2150명의 COVID-19 스페인 입원 환자의 정신 장애, 정신 약물 치료 및 사망률Article Published on 2021-06-012022-09-11 Journal: Acta psychiatrica Scandinavica [Category] SARS, 치료기술, [키워드] Adjustment disorder Admission age anonymously antidepressants Anxiety anxiolytics clinically COVID-19 COVID-19 infection de novo delirium depressive depressive disorder determine diagnosed diagnosing Diagnosis diagnosis of COVID-19 disorder disorders during admission functional hazard ratios history Hospital admission Hospital admissions hypnotics Inpatient lower mortality risk males Mental disorder Mental Disorders mental symptoms mood mood disorder Mortality mortality rate mortality risk Patient patients hospitalized PCR Prognosis Psychopharmacology Registered Spain Spanish Stress subject Symptom the disease Treatment university hospital [DOI] 10.1111/acps.13304 PMC 바로가기 [Article Type] Article
Predictors of infection, symptoms development, and mortality in people with SARS-CoV-2 living in retirement nursing homes은퇴 요양원에 거주하는 SARS-CoV-2 감염자의 감염, 증상 발생 및 사망률 예측인자Research Article Published on 2021-03-162022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] age Analysis Angiotensin II blocker chi-square test chronic chronic obstructive pulmonary disease Clinical data collected conducted correlated Cox proportional-hazards model death deaths dependent variable develop died Dyspnea enrolled evaluate evidenced Factor Fever foci Gender heparin high mortality hypokinetic disease increased risk Infection lower mortality risk lower risk male malignancies management Mental Disorders Mortality multivariate analyses Multivariate analysis neurological nursing homes Obstructive obstructive pulmonary disease pandemic Pearson Pearson chi-square test predictor predictors pulmonary disease receptor Retrospective study risk SARS-CoV-2 SARS-COV-2 infection Significant Spread Student’s t-test subjects Swab Symptom Symptoms syndrome Treatment variable was used with infection [DOI] 10.1371/journal.pone.0248009 PMC 바로가기 [Article Type] Research Article