Single-Cell Transcriptomic Profiling Identifies Molecular Phenotypes of Newborn Human Lung CellsArticle Published on 2024-02-262024-09-05 Journal: Genes [Category] update2024, [키워드] lung development matrix fibroblast newborn lung single-cell RNAseq [DOI] 10.3390/genes15030298 PMC 바로가기 [Article Type] Article
Organotypic human lung bud microarrays identify BMP-dependent SARS-CoV-2 infection in lung cellsarticle Published on 2023-04-202024-09-05 Journal: Stem Cell Reports [Category] update2024, [키워드] BMP signaling COVID-19 Endemic coronaviruses fetal lung lung buds lung development lung differentiation lung organoids micropatterned hESCs SARS-CoV-2 [DOI] 10.1016/j.stemcr.2023.03.015 PMC 바로가기 [Article Type] article
Clinical analysis and pluripotent stem cells-based model reveal possible impacts of ACE2 and lung progenitor cells on infants vulnerable to COVID-19임상 분석 및 만능 줄기 세포 기반 모델은 COVID-19에 취약한 유아에 대한 ACE2 및 폐 전구 세포의 가능한 영향을 보여줍니다Multicenter Study Published on 2021-01-012022-09-01 Journal: Theranostics [Category] 진단, 치료기술, [키워드] ACE2 ACE2 expression age Alveolar Type II analysed Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 biopsies Cell cells children children with COVID-19 clinical clinical feature Clinical features Cohort Combination contributing to cooperation coronavirus disease Coronavirus disease 2019 COVID-19 derivative develop developmental developmental stages disease severity distribution double positive cell double positive cells Ex vivo examined expressed expression expression level expression levels expression pattern expression patterns immune response immune system Impact Infant Infants infections lung lung biopsies lung cell lung cells lung development lung injuries Lung injury lung progenitor cells Lungs number of children Older pluripotent stem cells Pneumonia positive profiles progenitor cell progenitor cells reported risk factor Risk factors RNA-sequencing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pseudovirus SARS-CoV-2 virus severe coronavirus disease significantly single cell RNA sequencing SOX9 Spectrum Stage stem cell Type vulnerability with COVID-19 [DOI] 10.7150/thno.53136 PMC 바로가기 [Article Type] Multicenter Study