Nijmegen breakage syndrome: 25-year experience of diagnosis and treatment in UkraineImmunology Original Research Published on 2024-06-282024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] c.657_661del5 variant clinical analysis Diagnosis immunological characterization incidence malignancies NBN gene Nijmegen breakage syndrome [DOI] 10.3389/fimmu.2024.1428724 PMC 바로가기 [Article Type] Immunology Original Research
Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality—a national cohort studyClinical Science Published on 2024-04-132024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] Comorbidities Corticosteroids immunosuppressants infections malignancies Mortality organ damage Prednisolone SLE survival [DOI] 10.1093/rheumatology/kead348 PMC 바로가기 [Article Type] Clinical Science
Antibody response to a third booster dose of SARS-CoV-2 vaccination in adults with haematological and solid cancer: a systematic reviewArticle Published on 2022-11-012022-11-15 Journal: British Journal of Cancer [Category] COVID19(2023년), SARS, 진단, [키워드] access acute respiratory syndrome Affect Antibody Response anticancer association B-cell benefit booster booster dose booster vaccination Booster vaccine Cancer Coronavirus-2 depleting dose doses Efficacy evaluated Evidence haematological malignancies immunological responses include induce Infection malignancies morbidity and mortality organ Patient patients Patients with cancer receive recent risk SARS-CoV-2 SARS-CoV-2 vaccination Seroconversion significantly increased solid cancer systematic narrative review systematic review therapy vaccination [DOI] 10.1038/s41416-022-01951-y PMC 바로가기
The Complexity and Multiplicity of the Specific cAMP Phosphodiesterase Family: PDE4, Open New Adapted Therapeutic ApproachesArticle Published on 2022-09-132022-11-16 Journal: International Journal of Molecular Sciences [Category] 변종, [키워드] Adapted CAMP Cancer cardiovascular diseases cascade cellular cGMP complex complexity contribute COVID-19 cyclic cyclic nucleotide phosphodiesterase (PDE) Depression diabetes disease drug design dysregulation emesis Evolution Fatty liver increases in Inflammation inhibitor Interaction interactome knowledge maintain malignancies multiplicity New nucleotide obesity organ Osteoporosis overcome pathologic Pathologies phosphodiesterase Phosphorylation physiological state problems receptors Regulation Research selective selective PDE4 inhibitor (PDE4-I). Signaling Specific subcellular Therapeutic approach tissue ulcerative colitis variant various tissue [DOI] 10.3390/ijms231810616 PMC 바로가기
A retrospective cohort study of bladder cancer following the COVID-19 pandemic: Are patients presenting with more aggressive disease?Research article Published on 2022-09-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 바이오마커, [키워드] accounted Bladder cancer changes in COVID COVID-19 COVID-19 pandemic database demographics disease Diseases evaluate Follow-up Histopathology hospital invasive disease malignancies management many cases material New operative outcome pandemic Patient performed Potential presenting public health required resource Result retrospective cohort study study period the disease Treatment Uro-oncology Urology Urothelial cancer [DOI] 10.1016/j.amsu.2022.104430 [Article Type] Research article
Natural immunity to SARS-CoV-2 and breakthrough infections in vaccinated and unvaccinated patients with cancer Research Published on 2022-08-222022-10-05 Journal: British Journal of Cancer [Category] SARS, 치료법, [키워드] Breakthrough infection Cancer consecutive patient COVID-19 COVID-19 diagnosis death diagnosed diagnosed with COVID-19 Eligible participants European events Evidence Fatality rate haematologic malignancy highlighting Immunity Infection infections less malignancies malignancy median median time Mortality MOST natural observation period outcome Patient patients Patients with cancer patients with haematological Prevalence prevalence of COVID-19 recruited Reinfection reported required Result risk SARS-CoV-2 severity survivor Symptom therapy vaccination viral strains [DOI] 10.1038/s41416-022-01952-x [Article Type] Research
Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19심각하거나 치명적인 COVID-19에 대한 숙주 유전자 변이 및 감수성의 임상적 의미Review Published on 2022-08-192022-09-11 Journal: Genome Medicine [Category] SARS, 변종, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advanced age age allergy Asymptomatic disease clinical clinical implications Clinical management clinical picture Comorbidities convergence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical deficiency develop Effects expected Factor Genetic genetic finding genetic screening Genetic variant Genetic variation healthy individual heterogeneous Host host genetics human immune response IFN-I Immunity implication indicate Infectious disease interferon Male sex malignancies manifestation Mendelian disorder Mendelian disorders modulate pandemic pathogenic variant pathway Pathways Patient Pneumonia predisposition Prevalence rare variant Rare variants risk factor SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe manifestations of COVID-19 shown susceptibility susceptibility loci the interferon TLR7 virus X-linked [DOI] 10.1186/s13073-022-01100-3 PMC 바로가기 [Article Type] Review
Prevention and treatment of COVID-19 in patients with benign and malignant blood disordersReview article Published on 2022-08-012022-10-05 Journal: Best Practice & Research Clinical Haematology [Category] 변종, 치료법, 치료제, [키워드] B-cell Blood Blood cancer Cell chimeric antigen receptor Community complications COVID-19 COVID-19 in patient disease disorder hematologic Hemoglobinopathies high risk immunization immunosuppressed patient Immunosuppression initial lymphoid malignancies malignancy moderate NIH pathology Patient prevention receive regimen risk Safe SARS-CoV-2 severe immunosuppression T-cell Therapies therapy threshold Treatment Vaccine while [DOI] 10.1016/j.beha.2022.101375 [Article Type] Review article
COVID-19 mRNA Vaccine in Patients With Lymphoid Malignancy or Anti-CD20 Antibody Therapy: A Systematic Review and Meta-Analysis림프성 악성종양 환자 또는 항-CD20 항체 치료 환자의 코로나19 mRNA 백신: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-08-012022-09-11 Journal: Clinical lymphoma, myeloma & leukemia [Category] 치료제, [키워드] anti-CD20 antibody articles attenuate B-cell B-cell target therapy cellular response Cellular responses chronic lymphocytic leukemia CLL COVID-19 COVID-19 mRNA vaccine COVID-19 mRNA vaccines Effectiveness exhibited humoral Humoral and cellular responses Humoral response independent independent of individual leukemia Long-term follow-up Lymphocytic leukemia lymphoid lymphoma malignancies malignancy material Meta-analysis mRNA mRNA vaccine mRNA vaccines Myeloma Patient PROTECT registration number response to vaccination retrieved review risk risk ratio Seropositivity significantly subtype systematic review T cell T cell responses therapy These data vaccination Vaccine were used within 6 months [DOI] 10.1016/j.clml.2022.03.012 PMC 바로가기 [Article Type] Meta-Analysis
CA-125 monitoring in gynecologic cancer patients with COVID-19: A case seriesCase report Published on 2022-08-012022-10-05 Journal: Gynecologic Oncology Reports [Category] 바이오마커, [키워드] acute COVID-19 Analysis baseline Biomarker CA-125 Cancer cancer patient case sery clinical conditions conducted confounding effect COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 pandemic criteria elevated Elevation hospital Infection malignancies malignancy oncology ovarian Patient patient population patients patients treated retrospective severe COVID-19 infections Surveillance Treatment tumor marker uterine [DOI] 10.1016/j.gore.2022.101029 [Article Type] Case report