Natural SARS-CoV-2 Infection in a Free-Ranging Black-Tailed Marmoset (Mico melanurus) from an Urban Area in Mid-West Brazil브라질 중서부 도시 지역의 자유 범위 검은꼬리 마모셋(Mico melanurus)에서 자연적인 SARS-CoV-2 감염Article Published on 2022-06-012022-09-11 Journal: Journal of comparative pathology [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] alveolar septa animal Antigen Area Black-Tailed Marmoset Brazil clinical history COVID-19 female Hepatitis Host human populations immunohistochemistry Interstitial nephritis intestine large intestine liver lung lung tissue Lymph node Lymphocytes lymphoid marmoset Mild motor vehicle nasopharyngeal natural natural infection necropsy New World New World monkey nodule one health oropharyngeal swab pathogen Pathogens peribronchial periportal platyrrhines. Polytrauma pool Protein risk SARS-CoV-2 SARS-COV-2 infection Spike protein spleen state the viral nucleocapsid urban urban area viral nucleocapsid protein Viral RNA viral RNA detection [DOI] 10.1016/j.jcpa.2022.03.005 PMC 바로가기 [Article Type] Article
Characterization of SARS-CoV-2 Variants B.1.617.1 (Kappa), B.1.617.2 (Delta), and B.1.618 by Cell Entry and Immune Evasion세포 진입 및 면역 회피에 의한 SARS-CoV-2 변이체 B.1.617.1(카파), B.1.617.2(델타) 및 B.1.618의 특성화Article Published on 2022-04-262022-09-11 Journal: mBio [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] ACE2 ACE2 decoy receptor ACE2 orthologs ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition alteration angiotensin antibody Antiviral B.1.617.1 B.1.617.2 B.1.618 binding binding affinity causative agent cell entry characterization cleavage contribute convalescent sera coronavirus COVID-19 Delta delta variant E484K Efficiency Entry inhibitor entry inhibitors examined exhibited facilitate highlight host tropism human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 immune Immunity India Kappa variant L452R marmoset mouse Mutation neutralization neutralization antibodies Neutralization antibody neutralization titer Neutralizing antibodies neutralizing antibody P681R pandemic Patient receptor reduced SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sensitivity sera significantly increased Spike protein Spike proteins Spread T478K the spike protein Transmissibility vaccinated individual vaccinated individuals variant variants viral entry wild-type [DOI] 10.1128/mbio.00099-22 PMC 바로가기 [Article Type] Article
Comparison of Experimental Middle East Respiratory Syndrome Coronavirus Infection Acquired by Three Individual Routes of Infection in the Common MarmosetPathogenesis and Immunity Published on 2021-12-152022-10-30 Journal: Journal of Virology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Callithrix jacchus Acquired acute respiratory syndrome aerosol route Aerosols animal animal model breathing difficulties Callithrix caused challenge characterized common complications Concentration coronavirus cough demonstrated described disease emerging disease England Erasmus Fatality rate Fever Host host response Human Immunological response individual interstitial pneumonia intranasal Lung disease lung tissue Macrophage macrophages marmoset medical countermeasure MERS-CoV Middle East Middle East respiratory syndrome Mild neutrophil function Neutrophils Pneumonia Pyrexia renal respiratory respiratory syndrome coronavirus route SARS-CoV-2 severity Shortness of breath strain syndrome the disease throat swab upregulation Viable virus were used [DOI] 10.1128/jvi.01739-21 PMC 바로가기 [Article Type] Pathogenesis and Immunity
Utility of Common Marmoset ( Callithrix jacchus ) Embryonic Stem Cells in Liver Disease Modeling, Tissue Engineering and Drug MetabolismReview Published on 2020-06-302023-08-30 Journal: Genes [Category] E형 간염, [키워드] Callithrix jacchus bioengineering Cell therapy cytochrome P450 drug metabolism embryonic stem cell hepatocyte liver Liver disease marmoset regeneration transplantation [DOI] 10.3390/genes11070729 PMC 바로가기 [Article Type] Review
Infection with MERS-CoV Causes Lethal Pneumonia in the Common MarmosetResearch Article Published on 2014-08-212022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] addition Analysis animal model cause common Comorbidities comparable complicate demonstrated different time point Dipeptidyl peptidase 4 disease Disease model Efficacy evaluate expression Extensive humans immune inflammatory pathways Interaction intranasal lack lesion lethal lung marmoset marmoset model MERS-CoV MERS-CoV infection Middle East Mild modeling moderate disease MOST ocular Pathogenesis post inoculation potential therapeutic agent predicted Protein receptor required respiratory syndrome coronavirus rhesus RNAseq robust severe disease severe pneumonia severity spike glycoprotein the disease translated treated treatment strategy Vaccine Viral load virus entry was tested while [DOI] 10.1371/journal.ppat.1004250 PMC 바로가기 [Article Type] Research Article