Defying the odds: Determinants of the antimicrobial response of Salmonella Typhi and their interplayarticle Published on 2024-02-282024-09-01 Journal: Molecular Microbiology [Category] 살모넬라증, [키워드] MDR persistence QRDR quinolone-resistant XDR [Article Type] article
Computational analysis of RNA methyltransferase Rv3366 as a potential drug target for combating drug-resistant Mycobacterium tuberculosisMolecular Biosciences Original Research Published on 2024-01-112024-09-05 Journal: Frontiers in Molecular Biosciences [Category] update2024, [키워드] Droxidopa Levodopa MDR MTases TB XDR [DOI] 10.3389/fmolb.2023.1348337 PMC 바로가기 [Article Type] Molecular Biosciences Original Research
Multicenter study on the prevalence of colonization due to carbapenem-resistant Enterobacterales strains before and during the first year of COVID-19, Italy 2018–2020Public Health Original Research Published on 2023-12-192024-09-05 Journal: Frontiers in public health [Category] update2024, [키워드] Antibiotic-resistance carbapenem-resistant infections CRE Enterobacterales ICU Italy MDR Prevalence [DOI] 10.3389/fpubh.2023.1270924 PMC 바로가기 [Article Type] Public Health Original Research
Tools to Alleviate the Drug Resistance in Mycobacterium tuberculosisArticle Published on 2022-10-172022-11-15 Journal: Molecules [Category] 진단, [키워드] acid-fast bacillus Antibiotics Asymptomatic cause caused COVID-19 pandemic death detect diagnosed Diagnosis drug Drug discovery drug resistance drug-resistant estimates exhibiting Factor Frequency highlight Host intrinsically isolate isolates majority MDR molecular mechanism mutations Mycobacterium Mycobacterium tuberculosis Nucleic acid detection pathogen reduced reduction in resistance Treatment treatment regimen Tuberculosis WHO [DOI] 10.3390/molecules27206985 PMC 바로가기
Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strainsArticle Published on 2022-10-032022-11-16 Journal: World journal of microbiology & biotechnology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Amikacin analyzed antibiotic Antibiotic-resistance Antibiotics Bacteria Bacterial infection Bacterial infections calculated Cell cholesterol Concentration Coverage cytotoxicity drug resistance drug-resistant evaluated Gene Expression highest hospitalized patients IMPROVE inhibited Klebsiella Klebsiella pneumoniae less MBC MDR mechanism mRNA expression multi-drug resistant Niosome Niosome. occur positive ranged reduced SARS-CoV-2 significantly Spread stability strain Strains Toxicity Treatment were measured [DOI] 10.1007/s11274-022-03405-2 PMC 바로가기
Activity of ertapenem/zidebactam (WCK 6777) against problem EnterobacteralesArticle Published on 2022-09-302022-11-16 Journal: Journal of Antimicrobial Chemotherapy [Category] SARS, 비임상, [키워드] 1:1 active against activity administration breakpoint Dilution E. coli Escherichia coli evaluated experiments group healthcare increasingly indicated Infection inhibited isolate Klebsiella KPC Laboratory material MDR National nosocomial Outpatient over Parenteral pathogen Patient proportion regimen SARS-CoV-2 secondary submitted Support susceptibility Trial will drive [DOI] 10.1093/jac/dkac280 PMC 바로가기
Antimicrobial Activity of Ceftaroline and Comparator Agents Against Ceftriaxone-Nonsusceptible Streptococcus pneumoniae from the United States (2008-2020)article Published on 2022-09-302024-09-01 Journal: Microbial Drug Resistance [Category] 폐렴구균 감염증, [키워드] Ceftaroline ceftriaxone cephalosporin MDR PCV Pneumococo [Article Type] article
Lipocalin-2 is an essential component of the innate immune response to Acinetobacter baumannii infectionArticle Published on 2022-09-022022-11-16 Journal: PLoS Pathogens [Category] 유전자 메커니즘, [키워드] Acinetobacter acquisition antimicrobial drug Bacteremia Bacterial bloodstream infection caused change characteristic COVID-19 pandemic Critical curtail dissemination essential nutrient evaluated exhibited expand expression expression pattern feasible gene encoding Gene Expression Gram-negative bacteremia growth Health healthcare homeostasis Host host gene expression Immunity impairment include induce Infection inhibit inhibiting innate immune response involved lack Lcn2 lipocalin-2 MDR mechanism mice Mortality multidrug resistant multifactorial organ organ-specific pathogen Pneumonia Prevalence proliferation Protective Protein required reveal robust S100A8 S100A9 secondary bacterial pneumonia sequestering survival target therapeutic tissues Transcription transcriptional Treatment upregulated ventilated patient Ventilator-associated pneumonia were infected World Health Organization [DOI] 10.1371/journal.ppat.1010809 PMC 바로가기
Population structure of Mycobacterium tuberculosis from referral clinics in Western Siberia, Russia: Before and during the Covid-19 pandemicResearch article Published on 2022-09-012022-10-05 Journal: Infection, genetics and evolution : journal of mol [Category] 유전자 메커니즘, 치료기술, [키워드] analyzed association Beijing Beijing genotype changes in clinics collected COVID-19 decrease detection rate drug resistance Factor feature Genotype genotyping Health Hypothesis impacted incidence increase in isolate isolates Local MDR Mycobacterium tuberculosis pandemic Patient Population Prevalence proportion reduced resources Russia Siberia Tuberculosis while [DOI] 10.1016/j.meegid.2022.105343 [Article Type] Research article
Transcontinental spread and evolution of Mycobacterium tuberculosis W148 European/Russian clade toward extensively drug resistant tuberculosis Research Published on 2022-08-302022-10-05 Journal: Nature Communications [Category] 변종, [키워드] acquisition Analysis antibiotic average Bayesian changes in clade compensatory mutation complex distributions drug drugs Epidemic Eurasia Evolution Factor Genetic Genome sequencing isolate Lineage locus MDR MDR-TB Mortality Mutation Mycobacterium tuberculosis Prevalence regimens responsible Spread strain Strains Tolerance Transmission Tuberculosis widespread [DOI] 10.1038/s41467-022-32455-1 [Article Type] Research