TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replicationArticle Published on 2024-06-172024-09-05 Journal: bioRxiv [Category] update2024, [키워드] antiviral activity Apoptosis Caspase-6 E3-Ubiquitin ligases membrane protein SARS-CoV-2 TRIM7 ubiquitination [DOI] 10.1101/2024.06.17.599107 PMC 바로가기 [Article Type] Article
The KxGxYR and DxE motifs in the C-tail of the Middle East respiratory syndrome coronavirus membrane protein are crucial for infectious virus assemblyarticle Published on 2023-11-092024-09-05 Journal: Cellular and Molecular Life Sciences [Category] update2024, [키워드] coronavirus Endoplasmic reticulum exit intracellular trafficking membrane protein Trans-Golgi network retention viral assembly [DOI] 10.1007/s00018-023-05008-y PMC 바로가기 [Article Type] article
Oral Administration of Universal Bacterium-Vectored Nucleocapsid-Expressing COVID-19 Vaccine is Efficacious in Hamstersarticle Published on 2023-03-142024-09-05 Journal: Microbiology Spectrum [Category] update2024, [키워드] bacterial vector COVID-19 membrane protein mouse nucleocapsid protein oral administration Oral vaccine SARS-CoV-2 single vector platform single vector platform vaccine Syrian hamster Vaccine vaccine vector [DOI] 10.1128/spectrum.05035-22 PMC 바로가기 [Article Type] article
Network analysis of the autophagy biochemical network in relation to various autophagy-targeted proteins found among SARS-CoV-2 variants of concernSARS-CoV-2 변종의 우려와 관련된 다양한 자가포식 표적 단백질에서 자가포식 생화학 네트워크의 네트워크 분석Article Published on 2023-03-012023-07-11 Journal: Journal of molecular graphics & modelling [Category] COVID19(2023년), [키워드] Centrality measurements membrane protein network analysis SARS-CoV-2 (SARS2) variants of concern [DOI] 10.1016/j.jmgm.2022.108396 PMC 바로가기
Characterizing the Specific Recognition of Xanthurenic Acid by GEP1 and GEP1-GCα Interactions in cGMP Signaling Pathway in Gametogenesis of Malaria ParasitesArticle Published on 2023-01-292024-08-27 Journal: International Journal of Molecular Sciences [Category] 말라리아, [키워드] AlphaFold2 gametogenesis GCα GEP1 membrane protein protein interaction
SARS-CoV-2 cell entry beyond the ACE2 receptorArticle Published on 2022-11-012022-11-16 Journal: Molecular biology reports [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 expression ACE2 receptor AGTR2 ASGR1 Asymptomatic auxiliary B.1.1.529 B.1.1.7 B.1.617.1 B.1.617.2 binding carried CD147 CD26 cell entry cell surface receptors CLEC4G Cochrane Library COVID19 Delta Delta+ develop English enzyme erythrocyte Evidence explain facilitate host cell Hypoxemia Infection KREMEN1 LDLRAD3 membrane protein MeSH term neuropilin omicron organs Protein receptor receptors S protein SARS-CoV-2 SARS-CoV-2 cell SARSCoV-2 selected target therapeutic agent tissue tropism TMEM30A Transmission variants of SARS-CoV-2 viral entry virus entry [DOI] 10.1007/s11033-022-07700-x PMC 바로가기
The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia FormationArticle Published on 2022-10-262022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome appear assays catalytic caused Cell cell-cell fusion cell-cell fusion assay cells cellular cellular component cellular membrane contribute coronavirus coronavirus SARS-CoV-2 Coronaviruses COVID-19 COVID-19 pandemic dead defend Defense Efficiency ENhance entry of SARS-CoV-2 examined Formation genetic knockout global public health host cell membranes IFITM IFITMs in viral include Infection inhibiting inhibitory activity innate immune innate immune response Integral interact Interaction interfere intrinsic knockdown lentivirus maturation mechanism membrane membrane protein MHV mouse hepatitis virus nuclear overexpression pandemic Plaque assay precursor prelamin A Prevent protease Proteases PROTECT Protective protective role Protein proteolytic proteolytic activity reduce required restriction factor restriction factor. SARS-CoV-2 SARS-CoV-2 pseudovirus infection shown spike Therapeutic benefit transmembrane protein viral infection viral infections virus virus entry viruses wild-type ZMPSTE24 [DOI] 10.1128/mbio.02543-22 PMC 바로가기
A Study on the Nature of SARS-CoV-2 Using the Shell Disorder Models: Reproducibility, Evolution, Spread, and AttenuationArticle Published on 2022-09-232022-11-16 Journal: Biomolecules [Category] SARS, 변종, [키워드] applied attenuation bat-CoV contagiousness coronavirus Coronaviruses correlated CoV COVID COVID-19 demonstrated disorder enzyme greater Hard immune system implication intrinsic Long COVID lung membrane protein Nature nucleocapsid protein nucleoprotein observation omicron pangolin Particle PID predicted PROTECT Replication Saliva SARS-CoV-2 shell supported tissues transmissions variant Viral load virion virulence virus [DOI] 10.3390/biom12101353 PMC 바로가기
Baculovirus-Free SARS-CoV-2 Virus-like Particle Production in Insect Cells for Rapid Neutralization AssessmentArticle Published on 2022-09-202022-11-15 Journal: Viruses [Category] SARS, 진단, [키워드] ACE2 Analysis antibodies antibody approach assays assessment binding candidate Cell cellular cellular assay donors enzyme evaluate expression expression plasmid expression vector flow cytometric fluorescent fusion genomic information GFP insect insect cell insect cells labeling membrane membrane protein monoclonal antibody NTA Particle plasmid transfection Production purification quantification Rapid required SARS-CoV-2 SARS-CoV-2 envelope secondary antibody sera Spike protein TEM therapeutic transmission electron microscopy vaccinated individuals virus Virus-like particle Virus-like particles (VLPs) VLP VLPs [DOI] 10.3390/v14102087 PMC 바로가기
Serum peptidome profiles immune response of COVID-19 Vaccine administrationArticle Published on 2022-08-242022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 진단, [키워드] activated acute respiratory syndrome administration Analysis analyzed Antigen Biomarker C1q caused CD59 CD99 Cellular immune response clinical trials collected Complete CoronaVac coronavirus Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccine Efficacy Evidence glycoprotein help hemoglobin humoral immune immune response immunization immunogenicity analysis individual information Laboratory linear Logistic regression MALDI-TOF membrane protein NAb neutralizing antibody pandemic participant peptide peptides Peptidome performed Platelet profile Protein provided random receiving receptor reported Research SARS-CoV-2 serum serum sample Significant statistical analysis subunits Support SVM vaccination Vaccine Vaccines [DOI] 10.3389/fimmu.2022.956369 PMC 바로가기