MERS coronavirus – Communicable Diseases Research

Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine

MVA-MERS-S 백신으로 후기 3차 면역 후 MERS-CoV-스파이크 특이적 B 세포 및 항체의 지속성

Article

Published on 2022-07-192022-09-11
Journal: Cell Reports Medicine [Category] MERS, 임상, 진단,

MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity

Article

Published on 2022-03-252022-11-01
Journal: Nature Communications [Category] COVID-19, MERS,

Recommendations for the Diagnosis, Prevention, and Control of Coronavirus Disease-19 in Children—The Chinese Perspectives

Pediatrics

Published on 2020-11-052022-10-31
Journal: Frontiers in Pediatrics [Category] COVID-19,

Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials

Research article

Published on 2020-10-012022-10-05
Journal: Medical Hypotheses [Category] 임상, 진단, 치료법,

[키워드] activate acute respiratory distress syndrome Alpha alveolar Anti-inflammatory therapy Anti-viral anti-viral effect anticoagulant therapy anticoagulation approach ARDS ARDSacute respiratory distress syndrome Bacterial Beta Blood C-reactive protein Care Cell chemokines clinical outcomes clinically Coagulopathy Comorbidities Computerized tomography concerning Coronaviruses COVID-19 COVID-19 infection CoVscoronaviruses criteria CRPC-reactive protein CTcomputerized tomography CXCL10chemokines CXCL9 cytokine D-dimer diagnose Diagnosis diagnostic DICdisseminated intravascular coagulation Digital Disseminated intravascular coagulation distress effective elevated emboli extreme General population GGOground glass opacities gluthathione ground glass opacities GSHgluthathione Health Health authority healthy help high mortality rate highest hypothetical ICUIntensive Care Unit identify IL-10interleukin 10 IL-12interleukin 12 IL-18interleukin 18 IL-1βinterleukin 1 beta IL-33interleukin 33 IL-6interleukin 6 IL-7Interleukin 7 IL-8interleukin 8 immune immune function immunomodulatory implementation increase in individual individuals Inflammation intensive care unit interleukin 1 beta Interleukin 10 interleukin 12 interleukin 18 interleukin 33 interleukin 6 Interleukin 7 interleukin 8 Intervention Isolation Ivermectin lactic dehydrogenase LDHlactic dehydrogenase LDLyme disease literature review Lyme disease macrophage activation syndrome MASmacrophage activation syndrome MERS coronavirus MERS-CovMERS coronavirus morbidity and mortality Multiorgan dysfunction N-acetyl-cysteine NACN-acetyl-cysteine NCPnovel coronavirus pneumonia New NF-κB novel coronavirus pneumonia NSnutritional support nutraceutical nutritional support organ outcomes oxygen Oxygenation pandemic Pathways Patient performed physical distancing Pneumonia precursor Prevent protocol questionnaire Randomized controlled trial randomized trial randomized, controlled trials required resource respiratory therapy resulting risk SARS-CoV-2severe acute respiratory syndrome coronavirus 2 scored screening questionnaire second Sepsis serum severe acute respiratory syndrome coronavirus 2 severe complication silent statistical statistically Stress sulforaphane Support Symptom symptomatic infection TGFβtransforming growth factor beta the disease therapy thrombotic event TNF-αtumor necrosis factor alpha transforming growth factor beta Transmission Treatment Treatment strategies tumor necrosis factor alpha ventilator vital sign Vitamin C WHOWorld Health Organization with COVID-19 World Health Organization
[DOI] 10.1016/j.mehy.2020.109851 [Article Type] Research article

Assessment of proton-coupled conformational dynamics of SARS and MERS coronavirus papain-like proteases: Implication for designing broad-spectrum antiviral inhibitors

ARTICLES

Published on 2020-09-212022-10-30
Journal: The Journal of Chemical Physics [Category] COVID-19, SARS,

Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic

Article

Published on 2020-07-012022-10-30
Journal: The lancet. Psychiatry [Category] COVID-19, Fulltext, MERS,

[키워드] 95% CI acute illness acute respiratory syndrome age Agitation Anxiety Anxiety Disorder Canada Case report caused China Chinese classification Confusion coronavirus Coronavirus infection Course COVID-19 COVID-19 pandemic database delirium Depression diagnose died discharge effect size employment Encephalitis Encephalopathy Evidence examined excluded fatigue finding FIVE follow-up time foundation France funding Hong Kong hospital hypoxic ICD-10 impairment inclusion criteria independent index indicated indirect effect individual infection with SARS-CoV-2 Insomnia intensive care irritability Japan laboratory-confirmed literature Mania Medical Research Council medium memory mental health mental illness MERS MERS coronavirus MERS-CoV Meta-analysis meta-analytical Middle East Neurological complication Neuropsychiatric NHS NIHR Nursing outcome outcomes participant Patient patients patients with COVID-19 patients with SARS peer-reviewed study physical distancing measure Post-traumatic stress disorder Prevalence proportion Psychiatric PsycINFO quarantine random-effects model ranged reported researcher returned SARS Coronavirus SARS-CoV SARS-CoV-2 Saudi Arabia searched Self-isolation Seven Singapore sleep disorder South Korea Stage stratified Symptom syndrome systematic review the mean Trust University College London USA Wellcome Trust were assessed
[DOI] 10.1016/S2215-0366(20)30203-0 PMC 바로가기 [Article Type] Article

Immunogenicity of a DNA vaccine candidate for COVID-19

Article

Published on 2020-05-202022-10-04
Journal: Nature Communications [Category] MERS, 치료기술,

Selection of viral variants during persistent infection of insectivorous bat cells with Middle East respiratory syndrome coronavirus

Article

Published on 2020-04-292022-10-29
Journal: Scientific Reports [Category] COVID-19,

[키워드] acute respiratory syndrome basal bat bats Biological techniques Cell Cell Biology cells characterized coronavirus Coronavirus infection CoV Culture Dipeptidyl peptidase 4 disrupting DPP4 Eptesicus Evidence Evolution Frame Hypothesis in vitro individual infected cell infected cell culture Infection interactions interferon mathematical model mechanism MERS MERS coronavirus MERS-CoV Microbiology Middle East Molecular biology Mutation ORF5 persistence Population predicted Protein provide reduced respiratory syndrome coronavirus selected Selection Sequencing syndrome tested the interferon These cells transcripts type I interferon uninfected cells unique viral variant virus virus particles virus receptor virus replication whole genome wildtype
[DOI] 10.1038/s41598-020-64264-1 PMC 바로가기 [Article Type] Article

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

MERS-CoV 감염의 붉은털 원숭이 모델에서 예방 및 치료 렘데시비르(GS-5734) 치료

530

Published on 2020-03-242022-09-10
Journal: Proceedings of the National Academy of Sciences of [Category] MERS, SARS, 비임상,

[키워드] 2019-nCoV acute respiratory syndrome Administered animal model animals Antiviral Antiviral treatment antiviral treatments breath Case fatality rate caused clinical benefit clinical disease Clinical signs clinical trial clinical trials coronavirus Coronaviruses CoV infection damage effective Efficacy Fatality rate GS-5734 implementation in vitro inhibited initiated inoculation lung lung lesions Lungs MERS MERS coronavirus MERS-CoV MERS-CoV infection Middle East Middle East respiratory syndrome mouse model nCoV Novel coronavirus prevented Prophylactic provided reduced reduction in Remdesivir Replication respiratory Respiratory disease respiratory tissues rhesus rhesus macaque Severe acute respiratory syndrome severe respiratory disease severity Severity of disease shown Significance Support tested therapeutic therapy Treatment utility virus replication were infected Wuhan Wuhan, China
[DOI] 10.1073/pnas.1922083117 PMC 바로가기 [Article Type] 530

Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from Dubai

Observation

Published on 2020-01-222022-10-30
Journal: mSphere [Category] Coronavirus, MERS,