Microneedle-mediated nanomedicine to enhance therapeutic and diagnostic efficacyReview Published on 2024-04-182024-09-05 Journal: Nano Convergence [Category] update2024, [키워드] diagnostics drug delivery Microneedle nanomedicine Therapeutics [DOI] 10.1186/s40580-024-00421-w PMC 바로가기 [Article Type] Review
Potent immunogenicity and broad-spectrum protection potential of microneedle array patch-based COVID-19 DNA vaccine candidates encoding dimeric RBD chimera of SARS-CoV and SARS-CoV-2 variantsarticle Published on 2023-05-012024-09-05 Journal: Emerging Microbes & Infections [Category] update2024, [키워드] COVID-19 DNA vaccine Microneedle RBD chimera SARS-CoV-2 [DOI] 10.1080/22221751.2023.2202269 PMC 바로가기 [Article Type] article
Microneedle-based interstitial fluid extraction for drug analysis: Advances, challenges, and prospectsReview Paper Published on 2023-01-062024-09-05 Journal: Journal of Pharmaceutical Analysis [Category] update2024, [키워드] Biomarker Diagnosis interstitial fluid Microneedle Pharmaceutical analysis [DOI] 10.1016/j.jpha.2022.12.004 PMC 바로가기 [Article Type] Review Paper
Microneedle-based two-step transdermal delivery of Langerhans cell-targeting immunoliposomes induces a Th1-biased immune responseLangerhans 세포 표적 면역리포좀의 미세바늘 기반 2단계 경피 전달은 Th1 편향 면역 반응을 유도합니다Article Published on 2022-08-012022-09-12 Journal: European journal of pharmaceutics and biopharmaceu [Category] MERS, 진단, [키워드] activate affecting antibody Antigen Antigen presentation CD11c Cellular immune response Combination Compliance DCs dendritic cell effective Efficiency expected immune immune response immunization Immunoliposomes IMPROVE in vivo indicated induce inhibit Langerhans cell Langerhans cell targeting Liposome maturation Microneedle monoclonal monoclonal antibody novel produced promoted significantly stimulated survival Th1-biased immune response the epidemic Transcutaneous Transcutaneous immunization. tumor growth Vaccine [DOI] 10.1016/j.ejpb.2022.06.004 PMC 바로가기 [Article Type] Article
Feasibility of Enhancing Skin Permeability of Acyclovir through Sterile Topical Lyophilized Wafer on Self-Dissolving Microneedle-Treated SkinOriginal Article Published on 2022-05-162024-09-04 Journal: Dose-Response [Category] 대상포진, [키워드] acyclovir Microneedle polymer dissolution skin permeation topical lyophilized wafer [DOI] 10.1177/15593258221097594 PMC 바로가기 [Article Type] Original Article
The Nanoparticle-Enabled Success of COVID-19 mRNA Vaccines and the Promise of Microneedle Platforms for Pandemic Vaccine Response코로나19 mRNA 백신의 나노입자 기반 성공과 전염병 백신 대응을 위한 마이크로니들 플랫폼의 약속Section B: Infectious Diseases: Pathogenesis, Immune Responses, Vaccines, Diagnostics, and the Broad Impact of Them on Society Published on 2022-01-012022-09-10 Journal: DNA and Cell Biology [Category] 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen antigenic antigens approved biomaterials biomaterials and pandemic readiness cargo Cell Community coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 vaccines Critical critical mass Degradation disease effective effort Europe facilitate feature Health crisis immune responses Lipid management medical intervention Microneedle microneedle arrays for vaccination mRNA mRNA vaccine mRNA vaccines nanoparticles and COVID-19 vaccines nucleic acid nucleic acids Outbreaks pandemic Pathogens Perspective promise PROTECT Protective provided public health public health crisis reached readiness regions Research respiratory response SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Spike protein the United State the vaccine the vaccines translated Trigger triggers United States vaccination Vaccine Vaccines [DOI] 10.1089/dna.2021.0538 PMC 바로가기 [Article Type] Section B: Infectious Diseases: Pathogenesis, Immune Responses, Vaccines, Diagnostics, and the Broad Impact of Them on Society
Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines Against COVID-19COVID-19에 대해 DNA 나노백신을 보호하고 전달하는 분리형 마이크로니들 패치Article Published on 2021-09-282022-09-11 Journal: ACS Nano [Category] SARS, 치료법, [키워드] adaptive Adaptive immunity administration Against coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine decrease decreases DNA DNA vaccine DNA vaccines feature IFN-γ IgG IL-2 immune immune adjuvant Immune cell immune cells immune responses Immunity immunization in vivo Intramuscular injection lymph nodes Microneedle nucleic acid nucleic acid vaccine nucleocapsid pandemic patch Polymer Protein room temperature separable microneedle. significantly increased storage T cell T cells temperature tissue treated vaccination Vaccine Vaccines virus [DOI] 10.1021/acsnano.1c03252 PMC 바로가기 [Article Type] Article
Induction of Humoral and Cellular Immunity by Intradermal Delivery of SARS-CoV-2 Nucleocapsid Protein Using Dissolvable Microneedles용해성 미세바늘을 이용한 SARS-CoV-2 뉴클레오캡시드 단백질의 피내 전달에 의한 체액 및 세포 면역 유도Research Article Published on 2021-05-172022-09-10 Journal: Journal of Immunology Research [Category] SARS, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen B cell coronavirus CTL cytotoxic T lymphocyte delivery epitope Epitopes immunogenic induce induction Intradermal lymphocyte Microneedle nucleocapsid protein respiratory SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus skin patches T cell T cell responses Vaccine Viral viral infection [DOI] 10.1155/2021/5531220 PMC 바로가기 [Article Type] Research Article
Design of Dissolvable Microneedles for Delivery of a Pfs47-Based Malaria Transmission-Blocking VaccineArticle Published on 2021-05-102024-08-28 Journal: ACS Biomater Sci Eng [Category] 말라리아, [키워드] biomaterials immunology malaria Microneedle Plasmodium transmission-blocking vaccine
Dissolvable Microneedle Patches to Enable Increased Access to Vaccines against SARS-CoV-2 and Future Pandemic OutbreaksPerspective Published on 2021-04-012022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] access acute respiratory syndrome applied coronavirus coronavirus disease COVID-19 dissolvable microneedle patch drug delivery equity expected Future greater healthcare Immunity immunization implementation IMPROVE Increased Injections Microneedle Outbreaks pandemic reducing reduction SARS-CoV-2 skin vaccination vaccination Vaccine vaccine candidate vaccine delivery while [DOI] 10.3390/vaccines9040320 PMC 바로가기 [Article Type] Perspective