Targeting Mitochondrial Dynamics during Lower-Limb Ischemia Reperfusion in Young and Old Mice: Effect of Mitochondrial Fission Inhibitor-1 (mDivi-1)Article Published on 2024-04-042024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] aging ischemia reperfusion Lactate Mitochondria mitochondrial dynamics muscle Peripheral arterial disease reactive oxygen species [DOI] 10.3390/ijms25074025 PMC 바로가기 [Article Type] Article
Antioxidants and Calcium Modulators Preclude in Vitro Hepatitis B Virus–Induced Mitochondrial Damagearticle Published on 2023-10-012024-09-05 Journal: The Turkish Journal of Gastroenterology [Category] update2024, [키워드] antioxidant Calcium chelators Hepatitis B virus mitochondrial dynamics reactive oxygen species [DOI] 10.5152/tjg.2023.21290 PMC 바로가기 [Article Type] article
SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatoninArticle Published on 2021-03-012023-06-15 Journal: Pharmacology & therapeutics [Category] MERS, [키워드] adenosine monophosphate-activated protein kinase, AMPK Adenosine triphosphate, ATP angiotensin converting enzyme 2, ACE2 Apoptosis apoptosis inducing factor, AIF apoptosis protease-activating factor 1, Apaf-1 arylalkylamine N-acetyltransferase, AANAT autophagy autophagy related genes, ATGs caspase recruitment domains, CARDs Chaperone proteins Coronaviruses coronaviruses, CoVs COVID-19 deubiquitinating enzymes, DUBs double-stranded RNA, dsRNA fission fusion inner mitochondrial membranes, IMM interferon regulatory factor 3, IRF3 interleukin, IL long-OPA1, L-OPA1 mammalian target of rapamycin complex 1, mTORC1 melanoma differentiation-associated gene-5, MDA5 melatonin middle-east respiratory syndrome coronavirus, MERS-CoV mitochondrial associated antiviral signaling, MAVS mitochondrial DNA, mtDNA mitochondrial dynamics mitochondrial permeability transition pore, mPTP mitofusins, Mfn murine hepatitis virus, MHV NOD-like receptors protein 3, (NLRP3) open reading frame, ORF outer mitochondrial membrane, OMM papain-like protease, PLpro pathogen associated molecular patterns, PAMPs presequenced translocase-associated motor, PAM PTEN-induced putative kinase 1, PINK1 rabbit hemorrhagic disease virus, RHDV reactive oxygen species, retinoic acid-inducible gene I, RIG-I, ROS serotonin N-acetyltransferase, SNAT severe acute respiratory syndrome coronavirus, SARS-CoV short-OPA1, S-OPA1 translocase of the inner membrane, TIM translocase of the outer membrane, TOM transmissible gastroenteritis virus, TGEV Ubiquitin-proteasome system, UPS ULK1, (Unc-51-like kinase1) [DOI] 10.1016/j.pharmthera.2021.107825 PMC 바로가기 [Article Type] Article
Impact of COVID-19 on Mitochondrial-Based Immunity in Aging and Age-Related DiseasesNeuroscience Published on 2021-01-122022-10-31 Journal: Frontiers in Aging Neuroscience [Category] COVID-19, [키워드] acute respiratory syndrome age aging Alzheimer’s disease cardiovascular disease caused Cell cell death cell immunity chills chronic obstructive Clinical symptoms Comorbidity coronavirus coronavirus disease cough COVID-19 COVID-19 patients diabetes Diabetes Mellitus difficulty breathing Disease progression Evidence Fever headache help highlight homeostasis hypertension immune cells immune response Immunity Impact impair increase Increasing individual infected cell Interaction involved lifestyle likelihood Loss of Smell measure Mitochondria mitochondrial mitochondrial dynamics molecular mechanism Mortality mortality rate Neurological disease obesity Pain pandemic presence of comorbidity PROTECT pulmonary disease replicate Research SARS-CoV-2 Shortness of breath structures susceptible virus with COVID-19 [DOI] 10.3389/fnagi.2020.614650 PMC 바로가기 [Article Type] Neuroscience
Implications of Oxidative Stress and Potential Role of Mitochondrial Dysfunction in COVID-19: Therapeutic Effects of Vitamin DReview Published on 2020-09-212022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] Activation cell death cellular homeostasis consequence contagiousness contribute COVID-19 cytokine production Cytokines death decrease deficiency Effect Evidence Health IMPROVE individual Inflammation inflammatory process inflammatory state involved knowledge mitochondrial mitochondrial dynamics oxidative stress Potential pro-inflammatory state Prognosis provoke recent reduce Regulation renin-angiotensin-aldosterone system risk risk factor role ROS SARS-CoV-2 SARS-COV-2 infection syndrome virus Vitamin D vitamin D level [DOI] 10.3390/antiox9090897 PMC 바로가기 [Article Type] Review
Mitochondria Targeted Viral Replication and Survival Strategies—Prospective on SARS-CoV-2Pharmacology Published on 2020-08-282022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Activation Alter Apoptosis cellular cellular immunity cellular metabolism Community coronavirus Critical defend evade event functions highlight host cell immune activation immune response infected cell Infection MAVS mechanism metabolism Mitochondria mitochondrial mitochondrial dynamics modulate modulating molecular organelle platform positive proliferate regulated Regulation replicate RNA coronavirus RNA virus RNA viruses ROS SARS-CoV-2 Signaling Stress subcellular survival Vaccine virus viruses while [DOI] 10.3389/fphar.2020.578599 PMC 바로가기 [Article Type] Pharmacology
Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and GrowthArticle Published on 2020-01-042023-08-30 Journal: Cells [Category] E형 간염, [키워드] Liver cancer MFN1 mitochondrial dynamics OPA1 [DOI] 10.3390/cells9010121 PMC 바로가기 [Article Type] Article
HBx combined with AFB1 triggers hepatic steatosis via COX‐2‐mediated necrosome formation and mitochondrial dynamics disorderOriginal Article Published on 2019-07-072023-06-03 Journal: Journal of Cellular and Molecular Medicine [Category] B형 간염, [키워드] aflatoxin B1 cyclooxygenase‐2 hepatic steatosis hepatitis B virus X protein mitochondrial dynamics necrosome [DOI] 10.1111/jcmm.14388 PMC 바로가기 [Article Type] Original Article