Gene-by-gene screen of the unknown proteins encoded on Plasmodium falciparum chromosome 3Article Published on 2023-01-182024-08-27 Journal: Cell Syst [Category] 말라리아, [키워드] BioID evolution of genes kinetochore knock sideways malaria mitosis nucleus orphan genes Plasmodium falciparum protein function proteomics SKA taxon-specific proteins.
Griseofulvin: An Updated Overview of Old and Current KnowledgeArticle Published on 2022-10-182022-11-16 Journal: Molecules [Category] COVID19(2023년), SARS, 신약개발, 유전자 메커니즘, [키워드] ACE2 addition ascomycetes binding cancer cell capillary blood flow Cell contribute current derivative dermatophytic fungi disrupt domain Drug repurposing ENhance explain FDA-approved drug filament protein griseofulvin griseofulvin derivatives gsf gene cluster Hepatitis hepatitis C virus hepatocyte IMPROVE infections information inhibitory effect Inhibitory effects Interaction introduced K18 Liver injury Mallory mechanism metabolite metabolites mitosis molecular docking analysis multifunctional polyketide compound produced RBD RdRP Replication responsible RNA-dependent RNA polymerase rodent SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 main protease severity Spike protein spindle microtubule. therapeutic interventions treated Vascular viral replication [DOI] 10.3390/molecules27207034 PMC 바로가기
How Many Is Enough? – Challenges of Multinucleated Cell Division in Malaria Parasites얼마나 충분한가? - 말라리아 기생충의 다핵 세포 분열의 도전 과제Article Published on 2021-05-072024-08-08 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] cell division fungi malaria mitosis multinucleated Plasmodium polyploidy [DOI] 10.3389/fcimb.2021.658616 PMC 바로가기
Re-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with inflammatory responseResearch Paper Published on 2020-06-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] age Analysis caused cellular change chromosome segregation consequence Coronavirus disease 2019 COVID-19 COVID-19 patient Critical develop Health host cell human cells in vitro inflammatory reaction Inflammatory response investigated Lung injury mitosis network analysis outbreak pathway Pathway analysis Protein proteome proteomics proteomics data SARS-CoV-2 SARS-COV-2 infection severity Stage Symptom Treatment viral infection virus Wuhan, China [DOI] 10.18632/aging.103524 PMC 바로가기 [Article Type] Research Paper
Bluetongue virus infection induces aberrant mitosis in mammalian cellsResearch Published on 2013-10-282023-08-29 Journal: Virology Journal [Category] E형 간염, [키워드] Bluetongue mitosis Non-structural virus [DOI] 10.1186/1743-422X-10-319 PMC 바로가기 [Article Type] Research
Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen FamiliesPlasmodium falciparum의 유사분열 진화는 안정적인 핵심 게놈을 보여주지만 항원 가족에서 재조합을 보여줍니다Research Article Published on 2013-02-072022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] absence allele amplification Analysis anti-malarial drug Anti-malarial drugs antigenic variation atovaquone Author average base pair change chromosomal crossover chromosomal crossovers chromosome chromosome 1 clone clones Combination Complete core core genome cytochrome b death Deletion determined develop different disease drug drug pressure drug resistance drug target effort evade event Evolution family FIVE found Frequency Gene gene families genetic change Genetic changes Genome genomic alteration global health Haplotype Health help Host Host immune response host immune responses human host immune evasion immune resistance immune response immune responses IMPROVE in vitro increase individual level Infectious disease initiated involved malaria malaria parasites microarray technique mitosis mitotic mitotic recombination mrp1 Multidrug resistance multigene families multigene family Mutation mutation rate Mutation rates natural infection nucleotide occur P. falciparum parasite parasites Plasmodium Plasmodium falciparum plasticity populations presence or absence Protein Recombination recombination event Region responsible sequence variability show Single nucleotide variant single nucleotide variants STABLE strain Structural variant structural variants subtelomeric region subtelomeric regions var gene family whole-genome microarray whole-genome sequencing [DOI] 10.1371/journal.pgen.1003293 PMC 바로가기 [Article Type] Research Article
A Shared Role for RBF1 and dCAP-D3 in the Regulation of Transcription with Consequences for Innate Immunity타고난 면역에 대한 결과와 함께 전사 조절에서 RBF1 및 dCAP-D3의 공유 역할Research Article Published on 2012-04-052022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence activate Activation affected Alter AMP AMPs antimicrobial peptide Author Bacteria Bacterial infection Bacterial pathogens Cell cell cycle cell cycle arrest cell cycle gene cell cycle genes chromatin chromatin condensation classic Cluster condensation Condensin consequence conserved decrease DNA Drosophila Drosophila melanogaster expression fat function Gene gene cluster gene clusters Genes homolog homologs human cell human cells identify immune response immune system in vivo induce Infection Innate innate immune genes Innate immunity Interaction mitosis mitotic Pathogens peptide pRB previous study promote Protein Proteins RBF1 Region regulate regulated Regulation repress retinoblastoma retinoblastoma protein role shown subset subunit suggested transcript Transcription Tumor tumor suppressor undergo unique [DOI] 10.1371/journal.pgen.1002618 PMC 바로가기 [Article Type] Research Article