Maternal Immunization with Adjuvanted Recombinant Receptor-Binding Domain Protein Provides Immune Protection against SARS-CoV-2 in Infant MonkeysArticle Published on 2024-08-202024-09-05 Journal: Vaccines [Category] update2024, [키워드] antibody COVID-19 IgG Infant Monkey neutralization Placenta Receptor-binding domain Recombinant protein SARS-CoV-2 Vaccine [DOI] 10.3390/vaccines12080929 PMC 바로가기 [Article Type] Article
Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi말라리아 기생충 Plasmodium cynomolgi의 복제 형태에 감염된 간세포의 전사체 프로파일링Article Published on 2022-12-232024-08-01 Journal: Malaria Journal [Category] 말라리아, [키워드] host response Hypnozoites liver cells Monkey Relapsing malaria RNA sequencing Schizonts [DOI] 10.1186/s12936-022-04411-3 PMC 바로가기
Molecular diversity and phenotypic pleiotropy of ancient genomic regulatory loci derived from human endogenous retrovirus type H (HERVH) promoter LTR7 and HERVK promoter LTR5_Hs and their contemporary impacts on pathophysiology of Modern HumansArticle Published on 2022-11-012022-11-15 Journal: Molecular genetics and genomics : MGG [Category] SARS, 유전자 메커니즘, 진단, [키워드] affected Analysis Ape apes azoospermia Brain brain regions Cancer Cell cell type cells Central nervous system cognitive Consensus conserved coronavirus COVID-19 COVID-19 pandemic database defined disorders DNA sequence dominant element embryogenesis event Evidence Evolution expressed expression fetal functional gene signature Genes genes encoding Genome genomic germline global pandemic Glutamatergic GSEA HERV HERVs Human human cell Human embryogenesis human endogenous retrovirus Human endogenous retrovirus type H (HERVH) Human endogenous retrovirus type K (HERVK) human physiology Human spermatogenesis identification Impact implicated include Infection inheritance insertion Interaction Lineage loci LTR LTR5_Hs LTR7 subfamilies majority mammalian Mammalian offspring survival genes marker Metastasis Monkey morphological feature morphologically MOS naïve neoplasm Neoplasm metastasis Neural Neuron neurons New World non-human primates observation offspring Oligospermia pathogen pathology pathophysiology Phenotypes phenotypic physiological Pleiotropy Population population-level effect primate Primate evolution promoter protein-protein interaction Protein–protein interactions at synapses proteomics Quantitative Radial rare disease recessive regulated Regulatory regulatory element regulatory sequence Release replicate representing Retrotransposition retroviral retrovirus SARS-CoV-2 SARS-CoV-2 coronavirus Schizophrenia sequence significantly Spread Stage survival synaptic Synaptic transmission Synaptic transmission. target the SARS-CoV-2 timeline traits Transmission trigeminal undergo viral genome viral infection viral infections virus viruses [DOI] 10.1007/s00438-022-01954-7 PMC 바로가기
Preclinical safety evaluation and tracing of human mesenchymal stromal cell spheroids following intravenous injection into cynomolgus monkeysResearch article Published on 2022-10-012022-10-05 Journal: Biomaterials [Category] Coronavirus, 비임상, [키워드] addressed administration ambient Blood blood vessel Cell death demonstrated dissociate Efficacy feasible Host hypoxic condition injection intravenous Intravenous injection less lung Mesenchymal stem cells mice Monkey MSC MSCs multiple sclerosis occurred Osteoarthritis physiological change Preclinical promote retention Safe Safety Single Cell small blood vessel small vessel Spheroid Stress stromal cell survival viability wound healing [DOI] 10.1016/j.biomaterials.2022.121759 [Article Type] Research article
Feasibility Studies of Nebulized SARS-CoV-2 Neutralizing Antibody in Mice and Cynomolgus MonkeysArticle Published on 2022-09-012022-11-15 Journal: Pharmaceutical research [Category] COVID19(2023년), SARS, 진단, [키워드] aerosol alternative route animal model antibodies antibody antibody concentration approach caused Clinical studies Concentration demonstrated Diseases dose epithelial lining feasibility humanized monoclonal antibody inhalation intravenous Intravenous injection lung mice Mild Moderate COVID-19 Monkey nebulized Neutralizing neutralizing antibody pharmacokinetics PRNT reached remained respiratory tract safety profile SARS-CoV-2 SARS-COV-2 infection serum shown single dose Transport treating COVID-19 was used [DOI] 10.1007/s11095-022-03340-9 PMC 바로가기
Appearance and re-appearance of zoonotic disease during the pandemic period: long-term monitoring and analysis of zoonosis is crucial to confirm the animal origin of SARS-CoV-2 and monkeypox virusComment Published on 2022-06-072023-06-22 Journal: The Veterinary Quarterly [Category] COVID19(2023년), 조류인플루엔자, [키워드] bats intermediate hosts Monkey Monkeypox virus natural reservoirs. SARS-CoV-2 [DOI] 10.1080/01652176.2022.2086718 PMC 바로가기 [Article Type] Comment
Activation of Immune System May Cause Pathophysiological Changes in the Myocardium of SARS-CoV-2 Infected Monkey Model면역 체계의 활성화는 SARS-CoV-2에 감염된 원숭이 모델의 심근에 병태생리학적 변화를 일으킬 수 있음Article Published on 2022-02-102022-09-11 Journal: Cells [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] ACE2 receptor acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus analyzed cardiovascular cause change characterized collagen collected contagious contagious disease contribute coronavirus COVID-19 COVID-19 patients damages disease disorder eosin fibrosis foci heart heart failure heart tissue hearts hematoxylin Hematoxylin and eosin hypertrophy immunohistochemical staining induce Infection inflammatory cell inflammatory cells inflammatory immune response interstitial lead Lymphocytes Macrophage macrophages majority Model Monkey Myocardial myocarditis Myocardium pathological change pathological changes perivascular positive progression Region respiratory respiratory tract SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe complications staining subsequent System T lymphocyte T lymphocytes the disease tissue tissue sample ventricular virus virus particle virus particles [DOI] 10.3390/cells11040611 PMC 바로가기 [Article Type] Article
An enzyme-linked immunosorbent assay (ELISA) to determine Simian Varicella Virus antibody titers in infected rhesus monkeys (Macaca mulatta)Article Published on 2022-02-012023-05-31 Journal: Journal of medical primatology [Category] 두창, 수두, 홍역, [키워드] ELISA macaque Monkey simian varicella. SVV [DOI] 10.1111/jmp.12552
Observations on Food Consumption Behaviors During the COVID-19 Pandemic in OmanPublic Health Published on 2022-01-252022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] absence appear asked average Behavior Cohort conducted Consumption COVID-19 COVID-19 pandemic Descriptive statistics disseminate food food behavior food consumption Gulf Cooperation Council (GCC) Health healthy Impact increase in indicated Kruskal-Wallis Local Monkey observation Oman pandemic Panic participant platform question questionnaire reduced reduction respondent shown statistical test survey used to evaluate [DOI] 10.3389/fpubh.2021.779654 PMC 바로가기 [Article Type] Public Health
A Comparative Study of Chest CT With Lung Ultrasound After SARS-CoV-2 Infection in the Assessment of Pulmonary Lesions in Rhesus Monkeys ( Macaca Mulatta )Veterinary Science Published on 2021-10-292022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] abnormality assessment blinded Comparative Complete Computed tomography correlation COVID-19 CT findings Diagnosis diagnostic diagnostic value Diseases Efficacy female GGO GGOs Ground glass opacity Hospitalized humans infected with SARS-CoV-2 lesion Longitudinal assessment lung lung lobe Lungs macaques mild-to-moderate disease Monkey MOST non-human primate (NHP) Non-invasive nose/throat swab PCR positive post infection pulmonary Rhesus monkey Rhesus monkeys SARS-CoV-2 SARS-CoV-2 infected patients SARS-COV-2 infection scored sensitivity Ultrasound Volume [DOI] 10.3389/fvets.2021.748635 PMC 바로가기 [Article Type] Veterinary Science