Integrative analyses of genes about venous thromboembolism: An umbrella review of systematic reviews and meta-analysesArticle Published on 2022-10-282022-11-16 Journal: Medicine [Category] meta-analysis, 변종, [키워드] activating Analysis appraisal checklist conducted COVID-19 vaccination criteria Critical cumulative database Effect effect size eligible endothelial environmental risk factor Epidemiology estimates etiology Evidence Genetic genetic risk factor Genetic variant Genetic variations had more heterogeneity Human identify Intervention meta-analyses Meta-analysis MTHFR network p values performed polymorphism protease Protein prothrombin provided receptor respond review risk Risk factors Sample size selected surgical systematic review variable variant Venice venous Venous Thromboembolism VTE was performed were used [DOI] 10.1097/MD.0000000000031162 PMC 바로가기
CRVO associated with COVID-19 and MTHFR mutation in a 15-year-old maleCase report Published on 2022-06-012022-10-05 Journal: American Journal of Ophthalmology Case Reports [Category] 변종, 진단, [키워드] anterior chamber Cell Central retinal vein occlusion children complications of COVID-19 COVID-19 diagnostic edema etiologies excluded expand Extensive Gene Genetic hemorrhages hospital hypercoagulable Importance Infection Inflammatory initial knowledge Laboratory macular star male MTHFR Mutation Nasopharyngeal swab neuroretinitis observation ocular Patient positive provide retinal vein Viral load vitreous with COVID-19 [DOI] 10.1016/j.ajoc.2022.101522 [Article Type] Case report
MEDTEC Students against Coronavirus: Investigating the Role of Hemostatic Genes in the Predisposition to COVID-19 SeverityArticle Published on 2021-11-092022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] MTHFR 95%CI acute respiratory syndrome ADAMTS13 Analysis association Association analysis Characteristics characterized clinical heterogeneity Cohort conducted Control coronavirus coronavirus disease COVID-19 COVID-19 severity database degree distribution Engineering evidenced extreme functions General population Genes Genetic Genetic predisposition Hemostasis Hemostatic hemostatic genes Host intrinsic investigated Italian Manifestations median Medicine Meta-analysis MTHFR MTR pandemic performed polygenic risk score polymorphism predicted predisposition PROC Regeneron risk role SARS-CoV-2 severe COVID-19 severe COVID-19 patient severity significantly single-nucleotide student susceptibility THBS2 the disease Thromboembolic events university variant virus with COVID-19 [DOI] 10.3390/jpm11111166 PMC 바로가기 [Article Type] Article
Case report: cerebral sinus vein thrombosis in two patients with AstraZeneca SARS-CoV-2 vaccinationOriginal Communication Published on 2021-10-052022-10-29 Journal: Journal of Neurology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] AstraZeneca CD4 CD8 T cells cellular immunity Cerebral sinus vein thrombosis ChAdOx1 ChAdOx1 vaccine Contraception COVID-19 Deep venous thrombosis diagnosed Evidence female patient females headache heparin-induced thrombocytopenia humoral injection limit Mortality MTHFR mutations pandemic Patient SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination serious complication Thromboembolic event thrombosis vaccination Vaccine [DOI] 10.1007/s00415-021-10731-2 PMC 바로가기 [Article Type] Original Communication
Folic acid as placebo in controlled clinical trials of hydroxychloroquine prophylaxis in COVID-19: Is it scientifically justifiable?COVID-19에서 하이드록시클로로퀸 예방에 대한 통제된 임상 시험에서 위약으로서의 엽산: 과학적으로 정당화될 수 있습니까?Article Published on 2021-04-012022-08-31 Journal: Medical Hypotheses [Category] MERS, 임상, 치료제, [키워드] ACE2 benefit Clinical studies Combination complicate Controlled clinical trial COVID-19 cyanocobalamin disease severity domains Efficacy Factor failure Folic acid furin Hydroxychloroquine hypertension Hypothesis Interpretation Laboratory lowest Mild moderate disease MTHFR Other parameters Placebo placebo controlled trial polymorphism Prevalence Prophylaxis protease pulmonary hypertension Pyridoxine RCT reported SARS-CoV-2 Severe patient severe patients Trial Variation [DOI] 10.1016/j.mehy.2021.110539 PMC 바로가기 [Article Type] Article
Life-threatening course in coronavirus disease 2019 (COVID-19): Is there a link to methylenetetrahydrofolic acid reductase (MTHFR) polymorphism and hyperhomocysteinemia?생명을 위협하는 코로나바이러스 질병 2019(COVID-19) 과정: MTHFR(methylenetetrahydrofolic acid reductase) 다형성 및 고호모시스테인혈증과 관련이 있습니까?Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] 유전자 메커니즘, [키워드] carbon coronavirus disease Course COVID-19 COVID-19 pandemic develop disease severity distribution epidemiological data Gender Hyper-homocysteinemia hypothese hypotheses Hypothesis immune Interaction mechanism metabolism MTHFR MTHFR C677T One-carbon metabolism Pathomechanism polymorphism prophylactically resulting reveal risk factor Risk factors severe disease Spread tested [DOI] 10.1016/j.mehy.2020.110234 PMC 바로가기 [Article Type] Article
The MTHFR C677T mutation is not a risk factor recognized for HBV-related HCC in a population with a high prevalence of this genetic markerArticle Published on 2017-04-012023-06-16 Journal: Infection, genetics and evolution : journal of mol [Category] B형 간염, [키워드] Disease progression Hepatitis B virus Hepatocellular carcinoma MTHFR polymorphism [DOI] 10.1016/j.meegid.2017.01.008
Increased resistance to malaria in mice with methylenetetrahydrofolate reductase (Mthfr) deficiency suggests a mechanism for selection of the MTHFR 677C>T (c.665C>T) variantArticle Published on 2014-05-312024-09-10 Journal: Hum Mutat [Category] 말라리아, [키워드] cerebral malaria folate genetic selection Infection MTHFR PMC 바로가기