Bioinformatic elucidation of conserved epitopes to design a potential vaccine candidate against existing and emerging SARS-CoV-2 variants of concernResearch Article Published on 2024-07-232024-09-05 Journal: Heliyon [Category] update2024, [키워드] COVID-19 Immunogenic epitope Multi-epitope SARS-CoV-2 Vaccine design variants of concern [DOI] 10.1016/j.heliyon.2024.e35129 PMC 바로가기 [Article Type] Research Article
Development of an ancestral DC and TLR4-inducing multi-epitope peptide vaccine against the spike protein of SARS-CoV and SARS-CoV-2 using the advanced immunoinformatics approachesResearch Article Published on 2024-06-122024-09-05 Journal: Biochemistry and Biophysics Reports [Category] update2024, [키워드] computational immunology immunoinformatics Multi-epitope reverse vaccinology SARS-CoV SARS-CoV-2 [DOI] 10.1016/j.bbrep.2024.101745 PMC 바로가기 [Article Type] Research Article
Multi-epitope vaccine design for hepatitis E virus based on protein ORF2 and ORF3Microbiology Original Research Published on 2024-03-212024-09-05 Journal: Frontiers in Microbiology [Category] update2024, [키워드] HEV Multi-epitope ORF2 ORF3 Vaccine [DOI] 10.3389/fmicb.2024.1372069 PMC 바로가기 [Article Type] Microbiology Original Research
Design of a Multi-Epitope Vaccine against Histoplasma capsulatum through Immunoinformatics ApproachesArticle Published on 2024-01-052024-09-05 Journal: Journal of Fungi [Category] update2024, [키워드] Epizootic lymphangitis fungi vaccine Histoplasmosis Immunoinformatic Multi-epitope [DOI] 10.3390/jof10010043 PMC 바로가기 [Article Type] Article
Designing a multi-epitope vaccine against Peptostreptococcus anaerobius based on an immunoinformatics approachArticle Published on 2023-11-282024-09-05 Journal: Synthetic and Systems Biotechnology [Category] update2024, [키워드] Colorectal cancer Immunoformatics Multi-epitope PCWBR2 Peptostreptococcus anaerobius [DOI] 10.1016/j.synbio.2023.11.004 PMC 바로가기 [Article Type] Article
Designing of Multi-Epitope Peptide Vaccine Based on Outer Membrane Proteins OmpF, OmpC, and PgtE of Salmonella enterica Typhi살모넬라 엔테리카 장티푸스의 외막 단백질 OmpF, OmpC 및 PgtE를 기반으로 한 다중 에피토프 펩타이드 백신 설계Article Published on 2023-10-312024-08-21 Journal: Arch Razi Inst [Category] 살모넬라증, [키워드] in-silico Multi-epitope typhoid Vaccine
Designing, characterization, and immune stimulation of a novel multi-epitopic peptide-based potential vaccine candidate against monkeypox virus through screening its whole genome encoded proteins: An immunoinformatics approachArticle Published on 2022-11-012023-06-09 Journal: Travel medicine and infectious disease [Category] Fulltext, 원숭이두창, [키워드] immunoinformatics molecular docking Monkeypox virus (MPXV) Multi-epitope Peptide-based vaccine. [DOI] 10.1016/j.tmaid.2022.102481 PMC 바로가기
Design of a multi-epitope-based peptide vaccine against the S and N proteins of SARS-COV-2 using immunoinformatics approachResearch Published on 2022-02-042022-11-01 Journal: The Egyptian Journal of Medical Human Genetics [Category] COVID-19, [키워드] acquisition adjuvant adjuvants antigenic antigenic epitope antigenicity approach B cell B cell epitope C terminal cloned COVID-19 virus CTL develop E. coli epitope evaluated expression HTL identify immune response immunoinformatics Infection linker Mortality Multi-epitope Multi-epitope vaccine N protein non-allergenic non-toxic pandemic peptide predicted reduce Result SARS Coronavirus SARS-CoV-2 SARS-CoV-2 S protein selected supplementary material the vaccine three-dimensional structure Toxicity Vaccine vaccine construct were used [DOI] 10.1186/s43042-022-00224-w PMC 바로가기 [Article Type] Research
Immunoinformatics approach for multi-epitope vaccine design against structural proteins and ORF1a polyprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)Research Published on 2021-07-082022-10-28 Journal: Tropical Diseases, Travel Medicine and Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome amino acid sequence amino acids antigenic antigenicity approach candidate vaccine carried catastrophic cell-mediated immune chimeric clone coronavirus Coronavirus-2 COVID-19 CTL epitope docking E protein effective epitope Epitopes expression Final Health HTL epitope humoral IEDB immunoinformatics lack M protein molecular Multi-epitope Multi-epitope vaccine N protein ORF1a physicochemical property Plasmid polyprotein predict Protective Protein Proteins ProtParam tool Result S protein SARS-CoV-2 structural protein the vaccine TLR3 Treatment Vaccine Viral protein were used while [DOI] 10.1186/s40794-021-00147-1 PMC 바로가기 [Article Type] Research
Designing spike protein (S-Protein) based multi-epitope peptide vaccine against SARS COVID-19 by immunoinformaticsResearch article Published on 2020-11-162022-10-05 Journal: Heliyon [Category] 유전자 메커니즘, [키워드] AAY analysed antigenic approach B-cell bioinformatics China computational approach Concentration conducted COVID 19 COVID-19 COVID-19 infection criteria cytotoxic develop docking EAAAK linker effective effective drug Effectiveness epitope experiment expressed expression GPGPG help Humoral immunity immune response Immune simulation immunogenic immunoinformatics induce Interaction Laboratory linkers molecular docking Multi-epitope multi-epitope peptide vaccine outbreak peptide peptides physiochemical properties predicted Protein Proteins respiratory responsible SARS-COVID 19 scientist selected Spike protein T-cell TLR TLR3 TLR4 TLR9 vaccination Vaccine vaccine construct viral disease virus was performed was used β-defensin [DOI] 10.1016/j.heliyon.2020.e05528 [Article Type] Research article