Association between urea trajectory and protein dose in critically ill adults: a secondary exploratory analysis of the effort protein trial (RE-EFFORT)Research Published on 2024-01-162024-09-05 Journal: Critical Care [Category] update2024, [키워드] intensive care Joint modelling multi-organ failure Protein urea [DOI] 10.1186/s13054-024-04799-1 PMC 바로가기 [Article Type] Research
Acute liver injury in COVID-19 patients hospitalized in the intensive care unit: Narrative reviewReview Published on 2022-12-212023-07-11 Journal: World journal of gastroenterology [Category] COVID19(2023년), [키워드] COVID-19 Cytokine storm intensive care Liver injury multi-organ failure Pathophysiological mechanisms. [DOI] 10.3748/wjg.v28.i47.6662 PMC 바로가기 [Article Type] Review
Blood Endothelial-Cell Extracellular Vesicles as Potential Biomarkers for the Selection of Plasma in COVID-19 Convalescent Plasma TherapyArticle Published on 2022-10-042022-11-15 Journal: Cells [Category] 바이오마커, [키워드] Activation age anti-SARS-CoV-2 antibody Biomarkers Blood blood endothelium cardiovascular disease caused CCP CCP therapy Characteristics characterized clinical symptom Concentration consequence convalescent plasma Convalescent plasma therapy coronavirus disease COVID-19 death Donor downregulation Endothelial cell Endothelial dysfunction Endothelium evidenced excessive inflammation expected extracellular vesicle Extracellular vesicles extracellular vesicles. hospital ICAM1 identify individual infected individual inflammatory storm massive secretion mechanism mild symptoms mitochondrial dysfunction multi-organ failure onset of symptom overexpression parameter Peripheral blood plasma Potential pro-inflammatory pro-inflammatory cytokine progression promoted reflected selected Selection severity subset Symptoms the disease therapy vaccination Vascular endothelium vascular inflammation vessel was increased [DOI] 10.3390/cells11193122 PMC 바로가기
SARS-CoV-2 and the central nervous system: Emerging insights into hemorrhage-associated neurological consequences and therapeutic considerationsReview article Published on 2022-09-012022-10-05 Journal: Ageing research reviews [Category] COVID19(2023년), SARS, 비임상, [키워드] ACE2 angiotensin-converting enzyme 2 association Blood Brain brain fog cause caused cells cellular senescence comorbid conditions consequence Consequences coronavirus coronavirus 2 Coronavirus disease 2019 COVID COVID-19 Critical death Degradation Diseases event Ferroptosis Genome Genome instability hemorrhage hemorrhagic damage Increases individual lesion likelihood multi-organ failure neurodegenerative neurological Neurological complications Neurovascular occur organ pathology predisposition prognostic raise respiratory SARS-CoV-2 SARS-COV-2 infection senescence shown Strains Survivors systemic inflammation target therapeutic Therapeutic strategies widespread [DOI] 10.1016/j.arr.2022.101687 [Article Type] Review article
Circulating Ubiquitous RNA, A Highly Predictive and Prognostic Biomarker in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients순환 유비쿼터스 RNA, 입원한 코로나바이러스 질환 2019(COVID-19) 환자의 고도로 예측하고 예후가 좋은 바이오마커Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Admission Biomarker Biomarkers Blood cell lysis Chain Reaction circulating Clinical management clinical monitoring clinical outcomes Clinical severity coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patients Critical ddPCR death develop disease severity Diseases evaluate Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient Infectious diseases Invasive mechanical ventilation lung cell management marker multi-organ failure organ injury overall survival Patient plasma polymerase chain polymerase chain reaction predict Predictive predictive and prognostic biomarkers prognostic Prognostic biomarkers quantification respiratory respiratory distress Respiratory distress syndrome RNA RNase P RNAseP SARS-CoV-2 SARS-CoV-2 and RNAseP RNAemia severe acute respiratory syndrome Coronavirus severe and critical patients severity significantly survival syndrome tissue injury tissue/cell lysis biomarker. Viral [DOI] 10.1093/cid/ciab997 PMC 바로가기 [Article Type] Article
[Comparative study of patients hospitalized for SARS-CoV-2 infection in two consecutive waves in Tunisia]Article Published on 2022-08-182022-11-16 Journal: Médecine tropicale et santé internationale [Category] SARS, 변종, [키워드] acute respiratory distress affected age ARDS average average age cause circulation clinical form Comorbidities consequence coronavirus country COVID COVID-19 COVID-19 patient Critical death Deceased decrease Delta delta variant diabete English epidemic waves epidemiological data Étude Evolution Fatality rate feature forme French Gender global pandemic Health hospital Hospitalization Hospitalized hospitalized patient hypertension in both group intensive care less Maghreb management median multi-organ failure Northern Africa not significant nous Novel coronavirus Patient patients hospitalized prevalent Prospective Study SARS-CoV-2 SARS-COV-2 infection second wave Septic shock significantly significantly higher Sociodemographic successive wave symptoms onset syndrome the patient triggered Tunis Tunisia vaccination [DOI] 10.48327/mtsi.v2i3.2022.207 PMC 바로가기
Histidine-rich glycoprotein as a novel predictive biomarker of postoperative complications in intensive care unit patients: a prospective observational study중환자실 환자의 수술 후 합병증에 대한 새로운 예측 바이오마커로서의 히스티딘이 풍부한 당단백질: 전향적 관찰 연구Observational Study Published on 2022-07-202022-09-11 Journal: BMC Anesthesiology [Category] MERS, 바이오마커, 임상, [키워드] 95% confidence interval adjusted adjusted hazard ratio age Biomarker bleeding blood cell C-index C-reactive protein cardiovascular comorbidities Care classification Clavien–Dindo classification Complication complications coronavirus disease Coronavirus disease 2019 defined develop dysregulation fibrinolysis glycoprotein histidine Histidine-rich glycoprotein HRG immune systems incidence independent intensive care intensive care unit interquartile range intraoperative management median multi-organ failure observational study operative time Patient Perioperative Perioperative management Physical status Physical Status Classification Pneumonia postoperative Postoperative complication Postoperative Complications predict Predictive predictor preeclampsia Primary outcome procalcitonin prospective observational study reported secondary outcome Sepsis significantly lower single-center Society status surgery the patient Ventilator-associated pneumonia Volume White blood cell [DOI] 10.1186/s12871-022-01774-7 PMC 바로가기 [Article Type] Observational Study
Nasopharyngeal Bacterial Microbiota Composition and SARS-CoV-2 IgG Antibody Maintenance in Asymptomatic/Paucisymptomatic Subjects무증상/무증상 피험자의 비인두 세균성 미생물총 구성 및 SARS-CoV-2 IgG 항체 유지 관리Article Published on 2022-07-062022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adaptive immune response Analysis anti-RBD antibody Asymptomatic Asymptomatic carriers Bacterial best cause characterized condition coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 enrolment Evidence IgG antibody immune response immunoglobulins Immunological memory Infection influence investigated knowledge Lung injury maintenance mechanism microbiota multi-organ failure nasopharyngeal nasopharyngeal bacterial microbiota. Nasopharyngeal swab Odds ratio performed positive positive serology predict Regulation respiratory respiratory infection respiratory infections SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 infections SARS-CoV-2 RNA serum severe acute respiratory syndrome Coronavirus severity subject tested UNICORN Viral viral entry viral infections [DOI] 10.3389/fcimb.2022.882302 PMC 바로가기 [Article Type] Article
Long-term cardio-vascular risk assessment in chronic kidney disease and kidney transplanted patients following SARS-COV-2 disease: protocol for multi-center observational match controlled trial만성 신장 질환 및 SARS-COV-2 질환에 따른 신장 이식 환자의 장기 심혈관 위험 평가: 다기관 관찰 일치 대조 시험 프로토콜Article Published on 2022-05-062022-09-11 Journal: BMC Nephrology [Category] COVID19(2023년), SARS, 임상, [키워드] Acute kidney injury acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affecting angiotensin Angiotensin-converting enzyme association binding Biomarkers blood vessels Cardiac complications Cardio-vascular risk cardiovascular cardiovascular disease caused chronic Chronic kidney disease CKD clinical evaluation control group Controlled trial coronavirus coronavirus disease COVID-19 COVID-19 disease CVD database de novo death determine dialysis disease echocardiographic parameters Endothelial cell endothelial cells Endothelial dysfunction enrolment epithelial cells expected expressed focus heart higher risk implication incidence investigator investigators kidney Kidney disease kidney transplant lung mechanism multi-organ failure outcomes pandemic Patient patients pericyte pericytes podocyte produced protocol proximal pulse Pulse wave pulse wave velocity Registered renal risk risk factor SARS-CoV-2 SARS-COV-2 infection Sepsis severe acute respiratory syndrome Coronavirus severe disease Shock the disease therapeutic options Trial worse prognosis [DOI] 10.1186/s12882-022-02809-4 PMC 바로가기 [Article Type] Article
COVID-19 Vaccines in Pancreatic Transplant Recipients: A Single-Center Observative Study췌장 이식 환자의 코로나19 백신: 단일 센터 관찰 연구Article Published on 2022-05-012022-09-12 Journal: Transplantation proceedings [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] administration antibody Care Course COVID-19 COVID-19 virus death dose doses evaluate had no highest IgM and IgG Immunoglobulin immunosuppressive drugs Infection influenza-like symptom kidney Most patient mRNA vaccine multi-organ failure pancrea Patient performed PROTECT recipient respond response to vaccination Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic serious complication serum Severe infection the vaccine therapeutic Transplant vaccination [DOI] 10.1016/j.transproceed.2022.03.002 PMC 바로가기 [Article Type] Article