Case report: Febrile infection-related epilepsy syndrome in a 14-year-old girl with multiple organ failure and lethal outcomeNeuroscience Case Report Published on 2024-03-052024-09-05 Journal: Frontiers in Neuroscience [Category] update2024, [키워드] Fires multiple organ failure NORSE Pediatric neurology pediatric status epilepticus [DOI] 10.3389/fnins.2024.1255841 PMC 바로가기 [Article Type] Neuroscience Case Report
A Case of Acute Necrotizing Encephalopathy With Multiple Organ Failure Following COVID-19Neurology Published on 2024-01-042024-09-05 Journal: Cureus [Category] update2024, [키워드] Acute necrotizing encephalopathy COVID-19 cytokine intravenous methylprednisolone multiple organ failure Therapeutic plasma exchange [DOI] 10.7759/cureus.51665 PMC 바로가기 [Article Type] Neurology
Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic optionsReview Published on 2022-12-012023-07-10 Journal: International immunopharmacology [Category] COVID19(2023년), [키워드] COVID-19 Cytokine storm multiple organ failure oxidative stress Post-COVID-19 syndrome SARS-CoV-2 [DOI] 10.1016/j.intimp.2022.109428 PMC 바로가기 [Article Type] Review
Current evidence on the use of anakinra in COVID-19Review article Published on 2022-10-012022-10-05 Journal: International immunopharmacology [Category] COVID19(2023년), SARS, 바이오마커, 임상, 진단, 치료제, [키워드] acute respiratory distress syndrome administration Anakinra approval clinical evidence clinical status COVID-19 COVID-19 patient COVID-19 patients current cytokine cytokine release Cytokine release syndrome Cytokine storm dose early stage effective Evidence IL-1 IL-1 receptor antagonist Immunomodulatory agent include inhibit interleukin-1 intravenous knowledge management mechanical ventilation multiple organ failure off-label Prevent progression Remdesivir required secondary hemophagocytic lymphohistiocytosis shown syndrome the disease the SARS-CoV-2 therapeutic effect therapeutic effects therapy Treatment treatment approach viral replication [DOI] 10.1016/j.intimp.2022.109075 [Article Type] Review article
Risk factors of a severe course of pediatric multi-system inflammatory syndrome temporally associated with COVID-19Article Published on 2022-10-012022-11-15 Journal: European journal of pediatrics [Category] COVID19(2023년), SARS, 진단, [키워드] affecting age albumin biochemical parameter Blood C-reactive protein cardiovascular system cause changes in Child children clinical Complication Concentration Course creatinine CRP D-dimer defined disease disease severity Ejection fraction Factor Features ferritin higher risk Hospitalized hyponatremia identify imaging test Inflammation Inflammatory intensive care Intravenous immunoglobulin Laboratory Laboratory results Lymphocytes lymphopenia marker multiple organ failure myocardial damage NT-proBNP observation period parameter Patient Patient care patients PCT pediatric Pediatric patient PIMS Platelet procalcitonin required respond Retrospective study risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection serious complication severity single-center Standard therapy syndrome the disease the patient transfer Treatment triglycerides with COVID-19 [DOI] 10.1007/s00431-022-04584-8 PMC 바로가기
Cleavage-Responsive Biofactory T Cells Suppress Infectious Diseases-Associated HypercytokinemiaArticle Published on 2022-09-012022-11-15 Journal: Advanced Science [Category] 바이오마커, [키워드] activate administration Alpha Blood chimeric cleavage cleavage site coronavirus disease COVID-19 digestion Diseases domain drug endothelial engineered blood vessel engineered T cell enzyme EPCR Express expressing hypercytokinemia immune cells in vivo induce Infectious disease lentiviral system lung tissue multiple organ failure Necrosis overcome peptide Prevent Protein receptor Release Sepsis suppress T cell therapeutic thrombin receptor TRAP Treatment Vascular damage vessel [DOI] 10.1002/advs.202201883 PMC 바로가기
Durable functional limitation in patients with coronavirus disease-2019 admitted to intensive care and the effect of intermediate-dose vs standard-dose anticoagulation on functional outcomesRandomized Controlled Trial Published on 2022-09-012022-10-05 Journal: European journal of internal medicine [Category] COVID19(2023년), SARS, 임상, [키워드] affected airway anticoagulation clinical trial coronavirus coronavirus disease COVID-19 depressive symptom Depressive symptoms disease Exercise limitation Follow-up form functional Health Hospitalization ICU ICU patient impair IMPROVE intensive care intermediate limitation mental health multiple organ failure Odds ratio outcome outcomes participated Patient Patient health questionnaire-2 patients died patients with COVID-19 PHQ-2 Prophylactic prophylactic anticoagulation proportion Randomized Randomized controlled trial randomized patient Standard-dose Survivors The post-COVID-19 functional status scale. trial participants with COVID-19 women [DOI] 10.1016/j.ejim.2022.06.014 PMC 바로가기 [Article Type] Randomized Controlled Trial
Pathogenic Mechanism and Multi-omics Analysis of Oral Manifestations in COVID-19COVID-19의 구강 증상의 병원성 메커니즘 및 다중 오믹스 분석Review Published on 2022-07-042022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus Analysis bind caused clinical manifestation clinical manifestations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients cytokine Cytokines decrease droplets dysfunction dysregulation Factors Gustatory Host host cell host cells human ACE2 receptor immune immune cells immune dysregulation immune response Immunological analyses immunological analysis include infect Inflammation manifestation mount multi Multi-omics multiple organ failure Numerous oral oral cavity pathogen pathogenic phenotype reported respiratory distress respiratory infectious disease S protein Saliva SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 particle SARS-CoV-2 particles severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 Spread structural protein structural proteins syndrome the S protein Trigger virus Xerostomia [DOI] 10.3389/fimmu.2022.879792 PMC 바로가기 [Article Type] Review
Bleeding Complications in Patients With Perioperative COVID-19 Infection Undergoing Cardiac Surgery: A Single-Center Matched Case-Control StudyObservational Study Published on 2022-07-012022-10-05 Journal: Journal of cardiothoracic and vascular anesthesia [Category] 임상, [키워드] age bleeding Blood blood component body mass index cardiac Cardiac surgery Cardiopulmonary cardiopulmonary bypass Case-control chest tube Coagulation system Complication complications consecutive patient Control control group coronavirus Coronavirus 2019 correlation COVID-19 COVID-19 infection COVID-19 patient Deleterious described deviate diagnosis of COVID-19 died exacerbate Hemorrhagic Hemostasis incidence increased risk Infection inflammatory reaction intensive care intensive care unit Matched measurement multiple organ failure Non-COVID-19 patients operative risk outcome Patient patients without COVID-19 Perioperative positive postoperative previous study renal reported Respiratory failure retrospective severe respiratory failure Sex Shock significantly higher Society study group study period surgical the study group Thromboembolic events [DOI] 10.1053/j.jvca.2021.11.013 PMC 바로가기 [Article Type] Observational Study
Incidence and effects of deep vein thrombosis on the outcome of patients with coronavirus disease 2019 infectionObservational Study Published on 2022-07-012022-10-05 Journal: Journal of vascular surgery. Venous and lymphatic [Category] 임상, [키워드] 95% CI 95% confidence interval adjusted age Analysis anticoagulation ARDS Characteristics comparison contributing to coronavirus disease COVID-19 COVID-19 group COVID-19 patient COVID-19 patients Deep vein Deep vein thrombosis determine distress DVT Effect Factor ICU ICU Patients incidence increased mortality Infection intensive care Limited male Mortality multiple organ failure non-COVID-19 patient Observational cohort study occur outcome outcomes Patient patients with COVID-19 patients without COVID-19 performed Primary outcome Prophylactic receiving reported retrospective risk factor Standard Standard-dose surgical syndrome therapy Thromboprophylaxis thrombosis trauma trauma patient treated ventilatory support [DOI] 10.1016/j.jvsv.2021.10.013 PMC 바로가기 [Article Type] Observational Study