Interpatient variability in the pharmacokinetics of remdesivir and its main metabolite GS-441524 in treated COVID-19 subjectsArticle Published on 2022-09-302022-11-15 Journal: Journal of Antimicrobial Chemotherapy [Category] SARS, 치료제, [키워드] affected age antiviral drug approved association baseline blood sample BMI calculated collected comparison Concentration COVID-19 COVID-19 patients COVID-19 severity Efficacy enrolled evaluated glomerular filtration rate GS-441524 ICU identify independent predictor Inpatient Inpatients inter-individual Liver function Logistic regression metabolite Multiple linear regression Multiple regression analysis parameter Patient pharmacokinetic plasma Remdesivir renal renal function required Research SARS-CoV-2 SARS-CoV-2 infections Sex Standard-dose statistical subject transaminase treated Treatment Variability variables were assessed were measured were used [DOI] 10.1093/jac/dkac234 PMC 바로가기
Clinical factors affecting depression in patients with painful temporomandibular disorders during the COVID-19 pandemic Research Published on 2022-08-292022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] Affect affecting aggravate Anxiety arthralgia assessment axis BAI Beck clinical clinical factors COVID-19 COVID-19 pandemic Depression diagnosed disorder Factor Factors female females high correlation increase in intensity inventory investigated moderate multifactorial Multiple regression analysis myalgia negatively affected Novel coronavirus Pain pandemic Patient physical positively correlated Psychological Psychological distress recent Sex significantly significantly increased Stress stress level temporomandibular disorder TMD TMD pain was recorded [DOI] 10.1038/s41598-022-18745-0 [Article Type] Research
Increased Depression during COVID-19 Lockdown Associated with Food Insecurity and Antiretroviral Non-Adherence among People Living with HIV in Uganda우간다에서 HIV에 감염된 사람들의 식량 불안정 및 항레트로바이러스 비순응과 관련된 COVID-19 잠금 기간 동안의 우울증 증가Randomized Controlled Trial Published on 2022-07-012022-09-11 Journal: AIDS and Behavior [Category] 임상, 치료제, [키워드] 95% CI adherence Administered Analysis Antiretroviral therapy ART assessments bivariate analysis COVID-19 COVID-19 pandemic Depression depressive symptom Depressive symptoms disease distress dose economic Effect elevated enrolled examined female Follow-up food food insecurity greater Health help HIV HIV disease impacted Increased insecurity Intervention lack lack of food likelihood lockdown management mitigate money Multiple regression analysis pandemic participant PLHIV positive Qualitative qualitative data questionnaire Randomized controlled trial Rate reduced remained significantly increased Stress Stressor study period suggested threat turn Uganda unemployment with HIV [DOI] 10.1007/s10461-021-03371-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilationObservational Study Published on 2022-07-012022-10-05 Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 임상, [키워드] age ARDS Autoimmune disease Characteristics Clinical characteristics COVID-19 COVID-19 patient COVID-19 patients Critically ill determine Dexamethasone examined fungal Fungal infection ICU incidence Infection Invasive fungal infections Invasive mechanical ventilation mechanical ventilation mechanically ventilated men multicentre Multiple regression analysis not differ Patient Pneumonia receiving reported Retrospective study Standard of care Standard therapy superinfection Superinfections survival therapy with COVID-19 [DOI] 10.1016/j.jinf.2022.05.015 PMC 바로가기 [Article Type] Observational Study
The prevalence of nurse burnout and its association with telomere length pre and during the COVID-19 pandemic간호사 번아웃의 유병률과 COVID-19 전염병 이전 및 동안 텔로미어 길이와의 연관성Article Published on 2022-03-162022-09-11 Journal: PLoS ONE [Category] 유전자 메커니즘, [키워드] Administered Analysis analyzed Appropriate association Biomarker Blood blood sample Blood samples Burnout Care cellular change characterized collected coronavirus disease Coronavirus disease 2019 correlation Correlation analysis COVID-19 COVID-19 pandemic cross-sectional cross-sectional study Data collection decrease delivery demographics Depersonalization determine Effect Emotional exhaustion Epigenetic Final Health healthcare Healthcare system Healthcare systems hospital IMPROVE indicate Intervention inventory labor measure mechanism mental health Multiple regression analysis normality Nurse Nurses nursing care pandemic participant participated Patient care physical Prevalence prevalent promote Psychological reduced room Stress Symptom Symptoms syndrome telomere the mean took place two group unit was measured [DOI] 10.1371/journal.pone.0263603 PMC 바로가기 [Article Type] Article
An application of the extended parallel process model to protective behaviors against COVID-19 in South KoreaResearch Article Published on 2022-03-082022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] affecting analyzed applied COVID-19 Effect Efficacy Epidemics Factor hygiene implication individual Infectious disease information Multiple regression analysis no difference performed Protective response responses risk Self-efficacy severity social distancing Social distancing measure social distancing measures social environment South Korea susceptibility was used [DOI] 10.1371/journal.pone.0261132 PMC 바로가기 [Article Type] Research Article
A biopsychosocial model of severe fear of COVID-19Covid-19에 대한 심각한 두려움에 대한 생물 심리 사회적 모델Research Article Published on 2022-02-282022-09-10 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] aggravate aims Anxiety Attitude cause Contact contact with contribute COVID-19 Depression detect early stage Factor female gender female participant female participants finding Health Health anxiety illness inventory male participant male participants marital status media moderate Multiple Multiple regression analysis participant phobia Physical symptom physical symptoms predictor Psychological psychological factors Psychosocial factors questionnaire regression analysis respiratory respiratory infection Result risk social contact social media Social support Specific Specific Phobia STAI Support survey were infected with COVID-19 [DOI] 10.1371/journal.pone.0264357 PMC 바로가기 [Article Type] Research Article
Risk Perception among Psychiatric Patients during the COVID-19 PandemicObservational Study Published on 2022-02-242022-10-04 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] Administered Care conducted consecutive patient consequence Contagion COVID-19 COVID-19 pandemic cross-sectional Depression Diagnosis disorder Effectiveness event Health healthcare highlight Infection Italian Italian population Italy likelihood lockdown Multiple regression analysis New coronavirus non-COVID-19 patient Patient patients Perception Positive emotion positive emotions Prevent Psychiatric psychiatric patients Psychological questionnaire risk Risk perception Schizophrenia second wave seeking Support variable were assessed [DOI] 10.3390/ijerph19052620 PMC 바로가기 [Article Type] Observational Study
Clinical clerkship students’ preferences and satisfaction regarding online lectures during the COVID-19 pandemicResearch Published on 2022-01-182022-10-28 Journal: BMC Medical Education [Category] Coronavirus, SARS, [키워드] Affect average caused clinical Clinical clerkship conducted COVID-19 COVID-19 pandemic dimensions expected Factor Multiple regression analysis no difference Online lecture Online lectures outbreak outcomes pandemic preference preferences question Result Satisfaction score selected spread of COVID-19 student two group was determined [DOI] 10.1186/s12909-021-03096-7 PMC 바로가기 [Article Type] Research
Impact of COVID-19 Pandemic Exacerbation of Depressive Symptoms for Social Frailty from the ORANGE RegistryArticle Published on 2022-01-162022-10-30 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] 95% CI 95% confidence interval Analysis applied association baseline COVID-19 COVID-19 cases COVID-19 pandemic Depression depressive symptom Exacerbation Factor frailty group groups Impact implementation increase in individual Kruskal–Wallis test longitudinal study multiple logistic regression Multiple regression analysis Odds ratio Older Older adults performed predict Prevalence proportion recent registry reported rising robust significant difference social frail subject was performed [DOI] 10.3390/ijerph19020986 PMC 바로가기 [Article Type] Article