Video and In-Person Palliative Care Delivery Challenges Before and During the COVID-19 PandemicResearch article Published on 2022-08-012022-10-05 Journal: Journal of pain and symptom management [Category] 임상, [키워드] Analysis analyzed assigned associations Cancer Care challenge Characteristics clinician Context Coronavirus-19 COVID-19 COVID-19 pandemic Data analysis delivery described diagnosed in-person visit lung cancer multisite objective occurred palliative Palliative care pandemic Patient performed Randomized Randomly receive Result subgroup telehealth Telemedicine Trial worsened [DOI] 10.1016/j.jpainsymman.2022.08.005 [Article Type] Research article
Chemokines, soluble PD-L1, and immune cell hyporesponsiveness are distinct features of SARS-CoV-2 critical illness케모카인, 가용성 PD-L1 및 면역 세포 저반응은 SARS-CoV-2 중병의 뚜렷한 특징입니다Article Published on 2022-07-012022-09-12 Journal: American journal of physiology. Lung cellular and [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome ARDS C-reactive protein CCL17 CCL26 cellular checkpoint pathway chemoattractant comparison coronavirus disease Coronavirus-2 COVID-19 Critical Critically ill patient CRP CXCL10 demographics enrolled feature hyporesponsiveness identify IFN-γ IL-10 IL-17A IL-6 IL-8 immune Immune cell immune signature in vitro Interaction less lymphocyte Migration molecular monocyte mortality rate multisite not significantly different p value Patient patients patients without COVID-19 PD-L1 plasma Pneumonia profile prospective cohort Regulatory SARS-CoV-2 SARS-CoV-2-positive patient SARS-CoV-2-positive patients Sepsis severe respiratory failure severity subject subjects T cell T-cell TNF-α two groups ventilator-free day with COVID-19 [DOI] 10.1152/ajplung.00049.2022 PMC 바로가기 [Article Type] Article
Biotransformation and transplacental transfer of the anti-viral remdesivir and predominant metabolite, GS-441524 in pregnant rats임신한 쥐에서 항바이러스성 렘데시비르와 주요 대사산물인 GS-441524의 생체변환 및 태반 전이Article Published on 2022-07-012022-09-11 Journal: EBioMedicine [Category] 치료제, [키워드] amniotic Amniotic fluid Anti-viral approved AUC Biotransformation Blood Blood-placental barrier C max coronavirus disease Coronavirus disease 2019 COVID-19 cross during pregnancy evaluated fetus GS-441524 Hypothesis Liquid chromatography mass spectrometry maternal blood metabolite Microdialysis MONITOR mother multisite nucleoside parameter pharmacokinetic pharmacokinetics Placenta placental barrier predominant Pregnancy pregnant RATs Remdesivir Science shown Taiwan Tandem mass spectrometry technology tissues transfer treat Treatment UHPLC was used while [DOI] 10.1016/j.ebiom.2022.104095 PMC 바로가기 [Article Type] Article
Patients’ Perspectives on Emergency Department COVID-19 Vaccination and Vaccination Messaging Through Randomized VignettesRandomized Controlled Trial Published on 2022-07-012022-10-04 Journal: Public health reports (Washington, D.C. : 1974) [Category] 임상, [키워드] 95% CI age approach black Boston Care center Cincinnati Community conducted COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine cross-sectional survey Department Emergency emergency department female had no Health highest hospital hypothetical Influenza Intention multisite offer outcome participant Participants Patient patient population patients preventive intervention randomization Randomized receive the vaccine university vaccination Vaccine Vaccine hesitancy vaccine-hesitant [DOI] 10.1177/00333549221085580 PMC 바로가기 [Article Type] Randomized Controlled Trial
Developing and Implementing Electronic Consent Procedures in Response to Covid-19 RestrictionsCovid-19 제한에 대응하는 전자 동의 절차 개발 및 구현Article Published on 2022-07-012022-09-11 Journal: Ethics & human research [Category] 임상, [키워드] activity assent Complete Confusion Consent COVID-19 pandemic develop Developing electronic informed consent enrolled Families human research ethics human subjects research hybrid Implementing individual Informed consent informed consent. interactions lesson manuscript multisite pandemic participant pediatric procedure Research Research Ethics response restriction subject tested the United State trauma Trial type III United States utilization [DOI] 10.1002/eahr.500135 PMC 바로가기 [Article Type] Article
Evaluating the Ability to ID (COVID-19) NOW: a Large Real-World Prospective Evaluation of the Abbott ID NOW COVID-19 Assay(COVID-19) NOW 식별 능력 평가: Abbott ID NOW COVID-19 분석에 대한 대규모 실제 전향적 평가Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Abbott Ability Admitted Patient admitted patients Affect applicability assist Canada chain changed Cohort Community COVID-19 COVID-19 admission Critical decrease disease dual epidemiological evaluated Evaluating facilitate Factor Factors false negatives False positive highest hospital ID NOW increase in individual infection control Laboratory limitation molecular test multisite Negative predictive value not high pandemic Patient patient cohorts POCT point-of-care positive predictive values presenting Prevalence Probability Prospective public health Rapid Rapid test rapid testing Rapid tests receipt reduced reference standard report Reporting reverse transcriptase reverse transcriptase PCR risk RT-PCR SARS-CoV-2 SARS-CoV-2 detection status Study design swabs symptom onset TAT theory Tolerance Transmission Triage true negative turnaround time turnaround times utility Variation variations Volume [DOI] 10.1128/spectrum.00513-22 PMC 바로가기 [Article Type] Article
COVID-19 and venous thromboembolism risk in patients with sickle cell diseaseShort communication Published on 2022-06-272022-10-05 Journal: Blood advances [Category] 진단, [키워드] adjusted adjusted relative risk baseline characteristics causes Cell confidence interval COVID-19 COVID-19 infection disease group Health Hospitalization Hospitalized increase life-threatening log multisite no significant difference Patient patients hospitalized Poisson regression model Research risk risk ratio robust SCD severe COVID-19 illness Severe COVID-19 Infection Thromboembolism Venous Thromboembolism VTE VTE risk with COVID-19 [DOI] 10.1182/bloodadvances.2022007219 [Article Type] Short communication
High SARS-CoV-2 seroprevalence among health care workers in Bamako referral hospitals: a prospective multisite cross-sectional study (ANRS COV11)Bamako 위탁 병원의 의료 종사자 사이에 높은 SARS-CoV-2 혈청 유병률: 전향적 다중 부위 단면 연구(ANRS COV11)Article Published on 2022-06-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] cross-sectional Health care worker multisite SARS-CoV-2 seroprevalence [DOI] 10.1016/j.cmi.2022.02.019 PMC 바로가기 [Article Type] Article
Clinical data mining reveals Gancao-Banxia as a potential herbal pair against moderate COVID-19 by dual binding to IL-6/STAT3임상 데이터 마이닝은 IL-6/STAT3에 대한 이중 결합에 의해 중간 정도의 CovID-19에 대한 잠재적 인 허브 쌍으로 간카오-밴 내증을 밝혀냅니다.Article Published on 2022-06-012022-08-31 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 유전자 메커니즘, 임상, 치료제, [키워드] activator Analysis applied association benzyl binding Bioinformatic Chinese Chinese medicines (CMs) clinical clinical records Commission coniferin coronavirus disease Coronavirus disease 2019 COVID-19 Critical cytokine Cytokine storm Data mining Defense demonstrated dual FIVE Frequency Gancao-Banxia Gene ontology genomes group highest IL-6 immune response immune responses indicated Inflammatory response ingredient inhibit interleukin interleukin-6 Interleukin-6 (IL-6) KEGG Kyoto licochalcone a Medicine Moderate COVID-19 moderate COVID-19 patients molecular docking multisite network network pharmacology Pathways patients piperazine potential mechanisms PPI protein-protein interaction provided quercetin quinone Radix reveal SARS-CoV-2 signal Signal transducer and activator of transcription Signal transducer and activator of transcription 3 (STAT3). signaling pathways STAT3 Support target targets the cytokine storm therapeutic efficacy therapy Transcription Viral were used [DOI] 10.1016/j.compbiomed.2022.105457 PMC 바로가기 [Article Type] Article
Demographic and clinical characteristics associated with variations in antibody response to BNT162b2 COVID-19 vaccination among healthcare workers at an academic medical centre: a longitudinal cohort analysis대학병원 의료진의 BNT162b2 COVID-19 예방접종에 대한 항체 반응의 변화와 관련된 인구통계학적 및 임상적 특성: 종단 코호트 분석Article Published on 2022-05-242022-09-12 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] absence Adults age Analysis anti-spike protein IgG antibody Antibody Response association average blood sample BNT162b2 Characteristics Clinical characteristics clinical factor clinical history cohort analysis Complete Course COVID-19 COVID-19 vaccination demographic determinant Diseases exhibited Factor female healthcare worker hypertension Immunity include inclusion criteria individual infected individual Infection Infectious diseases initial Linear model longitudinal cohort study Male sex mRNA vaccination multisite natural infection of BNT162b2 offer positive postvaccination R 2 remained responses SARS-COV-2 infection Sex significantly sustained USA vaccination Variation while [DOI] 10.1136/bmjopen-2021-059994 PMC 바로가기 [Article Type] Article