Role of Fc Core Fucosylation in the Effector Function of IgG1 Antibodies
IgG1 항체의 이펙터 기능에서 Fc 코어 푸코실화의 역할
Review
[키워드] ADCC
ADCP
antibody
Antigen
approved
B-cell
Cancer
Cell
cellular cytotoxicity
Clinical use
core
decrease
Dengue
disease severity
Effect
effector
Efficacy
ENhance
fetal
fucosylation
function
highlighting
human IgG1 Fc
humoral
Humoral response
IgG
IgG Fc
IgG1
IgG1 antibody
immune
in vitro
in vivo
Infection
Inflammatory diseases
knowledge
less
mAb
mAbs
Macrophage
mechanism
Modification
monoclonal antibody
N-glycan
natural immune response
natural killer
NK cells
parasites
phagocytosis
Platelet
polyclonal
polymorphonuclear neutrophil
pregnant women
Regulation
reported
role
SARS-CoV 2
Seven
shown
significantly
therapeutic
therapeutic antibodies
treat
virus
virus infection
[DOI] 10.3389/fimmu.2022.929895 PMC 바로가기 [Article Type] Review
[DOI] 10.3389/fimmu.2022.929895 PMC 바로가기 [Article Type] Review