NAb activity – Communicable Diseases Research

COVID-19 symptom severity predicts neutralizing antibody activity in a community-based serological study

COVID-19 증상 중증도는 커뮤니티 기반 혈청 연구에서 중화 항체 활성을 예측합니다

Article

Published on 2022-07-182022-09-11
Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료기술, 치료법,

Safety and immunogenicity of CoronaVac in people living with HIV: a prospective cohort study

HIV 감염자에 대한 CoronaVac의 안전성 및 면역원성: 전향적 코호트 연구

Article

Published on 2022-05-012022-09-12
Journal: The Lancet. HIV [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] adjusted age and sex antiretroviral baseline Brazil CD4 CD4 cell CD4 count Cell Complete Concentration concerning control group CoronaVac COVID-19 vaccine delayed response geometric mean titre highlight HIV HIV/AIDS IgG immunogenicity Immunosuppression IMPROVE inactivated increase in independent intramuscularly investigated IQR less median multivariable model NAb activity neutralising antibody outpatient clinic participant people with HIV positive prospective cohort study recruited reduced reported Safety SARS-CoV-2 IgG SARS-CoV-2 vaccine second dose serious adverse reaction Seroconversion seroconversion rates titre two-dose regimen university vaccination Vaccine vaccine administration vaccine dose vaccine immunogenicity Vaccines Viral load was collected with HIV
[DOI] 10.1016/S2352-3018(22)00033-9 PMC 바로가기 [Article Type] Article

Effect of an exercise bout before the booster dose of an inactivated SARS-CoV-2 vaccine on immunogenicity in immunocompromised patients

비활성화된 SARS-CoV-2 백신의 추가 접종 전 운동 시합이 면역 저하 환자의 면역원성에 미치는 영향

Randomized Controlled Trial

Published on 2022-03-012022-09-12
Journal: Journal of applied physiology (Bethesda, Md. : 198 [Category] COVID19(2023년), MERS, SARS, 임상, 진단,

[키워드] anti-SARS-CoV-2 assigned booster booster dose comparable consecutive patient control group COVID-19 COVID-19 vaccine Effect ENhance exercise exhibited Frequency geometric mean titer GMT group homologous IgG immunized Immunocompromised patient immunogenicity Immunosuppression in both groups inactivated Inactivated vaccine intervention group NAb activity Neutralizing antibodies neutralizing antibody occurred Patient performed physical physical activity positive randomized controlled study remained resistance exercise resistance exercise. S1/S2 SARS-CoV-2 SARS-CoV-2 vaccine selected serology Sinovac-CoronaVac spondyloarthritis tested the vaccine vaccination
[DOI] 10.1152/japplphysiol.00015.2022 PMC 바로가기 [Article Type] Randomized Controlled Trial

The Characterization of Disease Severity Associated IgG Subclasses Response in COVID-19 Patients

COVID-19 환자의 질병 중증도 관련 IgG 하위 분류 반응의 특성화

Immunology

Published on 2021-03-042022-09-11
Journal: Frontiers in Immunology [Category] SARS, 진단, 치료법,

[키워드] age analyzed antibodies Antibody Response Antigen Asymptomatic COVID-19 characterization chemokines Clinical outcome Comorbidities Comorbidity coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patient cytokine cytokine production Cytokines disease disease severity dysregulated immune response dysregulated immune responses Evidence had no hospitalized patient Host immune response Ig isotype Ig isotypes IgG IgG subclasse IgG subclasses IgG1 IgG3 IL-1β immune responses Immunoglobulin Increasing isotypes Mild moderate Multiple multiple cytokines NAb activity Nasopharyngeal swab negative correlation neutralizing antibody no effect nucleocapsid protein Patient positively correlated Protein RBD Receptor binding domain response SARS-CoV-2 serum severe cases severity Sex significantly T cell T cell response T cell responses Viral Viral load was related
[DOI] 10.3389/fimmu.2021.632814 PMC 바로가기 [Article Type] Immunology

A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity

SARS-CoV-2 감염 환자에 대한 종단 연구는 중화 항체와 COVID-19 중증도 사이에 높은 상관관계가 있음을 보여줍니다

Article

Published on 2021-01-062022-09-11
Journal: Cellular and Molecular Immunology [Category] Fulltext, MERS, 변종, 진단,

[키워드] absence anti-Spike IgG anti-spike IgG levels antibody Asymptomatic Cohort contribute coronavirus correlated strongly COVID-19 COVID-19 severity Critical cross-neutralization D614G mutation disease disease severity disease symptom elicited Endemic Europe exhibited forms generate had no Health policy heterogeneous high correlation human coronavirus human coronaviruses humoral Humoral response immune correlate immune correlates immune response immune responses individual Infection infections intensive care intensive care unit intensive care units live SARS-CoV-2 Mild symptom mild symptoms NAb NAb activity NAb titers NAbs neutralization neutralizing antibody other coronaviruses Particle Pathogenesis pathogenesis of SARS-CoV-2 Patient Prognostic markers Protective Protein pseudotyped public health qPCR Reinfection required retroviruses reveal SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected patient SARS-CoV-2-infected patients serum sample serum samples spike Spike protein the SARS-CoV-2 the spike protein understanding Vaccine development variant Viral viral infection viral surface
[DOI] 10.1038/s41423-020-00588-2 PMC 바로가기 [Article Type] Article

Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID-19 Patients

혈청학적 분석, 회복된 COVID-19 환자에서 매우 가변적인 SARS-CoV-2 중화 항체 활성 추정

Immunoassays

Published on 2020-09-112022-09-10
Journal: Journal of Clinical Microbiology [Category] SARS, 진단, 치료기술,

[키워드] 2019 Abbott Abbott SARS-CoV-2 IgG Accuracy activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-SARS-CoV-2 antibody antiviral activity center choice collected convalescent plasma convalescent plasma samples coronavirus coronavirus disease correlated COVID-19 Critical determine Donor ELISA ELISAs enrolled enzyme enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays estimate gold gold standard house IgG Immunity immunoglobin Infection Interpretation levels of antibodies levels of antibody methodology NAb NAb activity NAb assay NAb assays NAbs neutralization Neutralizing antibodies neutralizing antibody New York offer pandemic Particles patient sera Population population immunity predict Program proportion Pseudotyped virus recovered reopening respiratory SARS-CoV-2 SARS-CoV-2 detection Sensitivity and specificity serologic tests Serological assay serological assays serological measurement serological measurements serological test Serological tests serology Seroprevalence severe acute respiratory syndrome Coronavirus therapeutic therapeutic trials total Ig Trial unique vaccination variable Variation Viral viral infection
[DOI] 10.1128/JCM.02005-20 PMC 바로가기 [Article Type] Immunoassays