Racial and Ethnic Disparities in Buprenorphine and Extended-Release Naltrexone Filled Prescriptions During the COVID-19 PandemicArticle Published on 2022-06-012022-10-04 Journal: JAMA Network Open [Category] 신약개발, [키워드] analyzed Asian black Black patient Black patients Buprenorphine calculated categories COVID-19 COVID-19 pandemic cross-sectional database decrease disorder disparity ethnic group greater decrease group groups Hispanic include increases in individual individuals Interrupted Medicaid Medicare naltrexone outcome pandemic Patient patients prescription proportion Racial risk Significant stratified Treatment Weekly were used white White patient White patients [DOI] 10.1001/jamanetworkopen.2022.14765 PMC 바로가기 [Article Type] Article
Naltrexone a potential therapeutic candidate for COVID-19Article Published on 2022-02-012022-10-04 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발, [키워드] ACE2 approved binding bioinformatics clinical coronavirus 2 Coronavirus infection COVID-19 COVID-19 patients Cytokines storm disrupt docking downstream Drug repurposing global pandemic glycoprotein host cells host receptor Hyperinflammatory induce inhibit inhibitor Interaction interfere Like lung tissue macrophage cell molecular molecular docking multiple organ failure naltrexone other coronaviruses Phosphorylation positively correlated pro-inflammatory cytokine pro-inflammatory cytokine release pro-inflammatory cytokine storm Protein RBD reported required respiratory Respiratory failure SARS-CoV-2 SARS-COV-2 infection spike structural bioinformatics suppresse suppressed surface Spike tested the SARS-CoV-2 therapeutic therapy Toxicity Treatment viral entry viral infectivity viral replication virus load [DOI] 10.1080/07391102.2020.1820379 PMC 바로가기 [Article Type] Article
Syringe service program-based telemedicine linkage to opioid use disorder treatment: protocol for the STAMINA randomized control trial아편유사제 사용 장애 치료에 대한 주사기 서비스 프로그램 기반 원격 의료 연결: STAMINA 무작위 대조군 시험을 위한 프로토콜Study Protocol Published on 2021-03-312022-09-10 Journal: BMC Public Health [Category] 임상, [키워드] access All participant All participants Analysis approach ARMS baseline Buprenorphine center change Chicago clinical collected Complete conducted control arm COVID-19 pandemic detect disorder Effect engage Epidemic expand Expanded access Facilitating generalized linear regression health center include initial initial assessment Intervention intervention arm lead linear regression analyses medication Medication assisted treatment Medication for opioid use disorder medications Methadone naltrexone occurred open Open Science Framework opioid opioids outcome outcomes overdose participant platform Primary outcome Probability protocol provided Randomized receive recruit reduce Registered Regulatory retained risk Saliva secondary Secondary outcomes service significantly STAMINA Study protocol Substance use disorder survival survival analysis Syringe Syringe exchange telehealth Telemedicine telemedicine intervention telemedicine interventions Treatment treatment initiation Trial Trial registration [DOI] 10.1186/s12889-021-10669-0 PMC 바로가기 [Article Type] Study Protocol
Vaccine blunts fentanyl potency in male rhesus monkeysarticle Published on 2019-11-302024-09-01 Journal: Neuropharmacology [Category] 파상풍, [키워드] Antinociception fentanyl naltrexone Oxycodone Rhesus monkeys Vaccine [Article Type] article