Potential Inhibitors of Monkeypox Virus Revealed by Molecular Modeling Approach to Viral DNA Topoisomerase IArticle Published on 2023-02-022023-06-10 Journal: Molecules [Category] Fulltext, 원숭이두창, [키워드] DNA topoisomerase I (TOP1) enrichment analyses Molecular dynamics simulation Monkeypox virus natural products rosmarinic acid. surface plasmon resonance (SPR) [DOI] 10.3390/molecules28031444 PMC 바로가기
Genetically Encoded Detection of Biosynthetic Protease InhibitorsArticle Published on 2023-01-202023-07-11 Journal: ACS synthetic biology [Category] COVID19(2023년), [키워드] biological selection natural products non-ribosomal peptide synthetases SARS-CoV-2 viral proteases. [DOI] 10.1021/acssynbio.2c00384 PMC 바로가기
Exploration of Microbially Derived Natural Compounds against Monkeypox Virus as Viral Core Cysteine Proteinase InhibitorsArticle Published on 2023-01-162023-06-09 Journal: Viruses [Category] Fulltext, 원숭이두창, [키워드] antivirals molecular dynamics Monkeypox virus natural products virtual screening. [DOI] 10.3390/v15010251 PMC 바로가기
Neurological disorders of COVID-19: insights to applications of natural products from plants and microorganismsReview Published on 2022-12-012023-07-10 Journal: Archives of pharmacal research [Category] COVID19(2023년), [키워드] Drug discovery natural products Neurological complications SARS-CoV-2. [DOI] 10.1007/s12272-022-01420-3 PMC 바로가기 [Article Type] Review
Insights into Antiviral Properties and Molecular Mechanisms of Non-Flavonoid Polyphenols against Human HerpesvirusesReview Published on 2022-11-112023-06-02 Journal: International Journal of Molecular Sciences [Category] 두창, 홍역, [키워드] antiviral activity Epstein–Barr virus (EBV) herpes simplex virus HSV-1 HSV-2 human cytomegalovirus (HCMV) Kaposi sarcoma-associated herpesvirus (KSHV) natural products non-flavonoid polyphenols polyphenols varicella-zoster virus (VZV). [DOI] 10.3390/ijms232213891 PMC 바로가기 [Article Type] Review
Lucidenic acid A inhibits the binding of hACE2 receptor with spike protein to prevent SARS-CoV-2 invasionArticle Published on 2022-11-012022-11-15 Journal: Food and chemical toxicology : an international jo [Category] SARS, 변종, 치료제, [키워드] analyzed anti-SARS-CoV-2 antiviral effects binding caused complexes component components demonstrated exhibit FRET test Ganoderma lucidum triterpenoids hACE2 hACE2 receptor high affinity hydrogen bonds IC50 in vitro Infection inhibit inhibited inhibition assay Invasion Lucidenic acid A (PubChem CID: 14109375) molecular docking molecular dynamics Mutation natural natural products omicron Omicron variant omicron variant. pathway Potential Prevent PubChem receptor receptor proteins SARS-CoV-2 Spike protein stability target variant Virtual screening virus was selected were used [DOI] 10.1016/j.fct.2022.113438 PMC 바로가기
Renoprotective Effects of Luteolin: Therapeutic Potential for COVID-19-Associated Acute Kidney InjuriesReview Published on 2022-10-232023-07-10 Journal: Biomolecules [Category] COVID19(2023년), [키워드] coronavirus flavonoids medicinal plant natural products nephrotoxicity renal disease renoprotective effect. SARS-CoV-2 [DOI] 10.3390/biom12111544 PMC 바로가기 [Article Type] Review
In silico evaluation of Philippine Natural Products against SARS-CoV-2 Main ProteaseArticle Published on 2022-10-072022-11-15 Journal: Journal of molecular modeling [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] Activation acute respiratory syndrome ADME ADMET antiviral drug betweenness Betweenness centrality binding site catalytic dyad Clinical treatment complex coronavirus COVID-19 database docking experiments drugs enzyme highest in silico In silico methods in vitro in vivo inhibitor inhibitory inhibitory effect Ligand molecular docking molecular dynamics MPro mutated variant natural natural products network network analysis offer pandemic Population potential mechanism predicted product protease Protein reported residue responsible risk SARS-CoV-2 SARS-CoV-2. severe COVID-19 Spread the SARS-CoV-2 trajectory Vaccine Vaccines viral replication WHO World Health Organization [DOI] 10.1007/s00894-022-05334-1 PMC 바로가기
Fermented natural product targeting gut microbiota regulate immunity and anti-inflammatory activity: A possible way to prevent COVID-19 in daily dietReview article Published on 2022-10-012022-10-05 Journal: Journal of Functional Foods [Category] 변종, 치료제, [키워드] Active substances Anti-inflammation Anti-inflammatory anti-inflammatory activity Bacteria change COVID-19 Effect gut microbiota immune function Immunity Inflammation Influenza ingredient lipid metabolism modulating molecular mechanisms natural products organs Prevent Probiotics regulate shifting shown viruses [DOI] 10.1016/j.jff.2022.105229 [Article Type] Review article
Computational exploration of natural peptides targeting ACE2Article Published on 2022-10-012023-07-06 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), [키워드] ACE2 Molecular simulation natural products peptide SARS-CoV-2 virtual screening. [DOI] 10.1080/07391102.2021.1905555 PMC 바로가기