Plant-Produced Chimeric Hepatitis E Virus-like Particles as Carriers for Antigen PresentationArticle Published on 2024-07-082024-09-05 Journal: Viruses [Category] update2024, [키워드] hepatitis E virus Influenza M2e peptide Nicotiana benthamiana transient expression Vaccine Viral vector Virus-like particle [DOI] 10.3390/v16071093 PMC 바로가기 [Article Type] Article
Development of a Candidate TMV Epitope Display Vaccine against SARS-CoV-2Article Published on 2024-04-232024-09-05 Journal: Vaccines [Category] update2024, [키워드] epitope display vaccine Nicotiana benthamiana SARS-CoV-2 Spike protein tobacco mosaic virus [DOI] 10.3390/vaccines12050448 PMC 바로가기 [Article Type] Article
Neutralizing activity of anti-respiratory syncytial virus monoclonal antibody produced in Nicotiana benthamianaRsv Published on 2024-03-202024-09-05 Journal: Human vaccines & immunotherapeutics [Category] update2024, [키워드] germinivirus immunoprophylaxis, viral infection monoclonal antibody Nicotiana benthamiana Recombinant expression respiratory syncytial virus RSV-fusion protein [DOI] 10.1080/21645515.2024.2327142 PMC 바로가기 [Article Type] Rsv
Implications of O-glycan modifications in the hinge region of a plant-produced SARS-CoV-2-IgA antibody on functionalityarticle Published on 2024-03-062024-09-05 Journal: Frontiers in Bioengineering and Biotechnology [Category] update2024, [키워드] antibody glycoprotein glycosylation Nicotiana benthamiana posttranslational modification virus [DOI] 10.3389/fbioe.2024.1329018 PMC 바로가기 [Article Type] article
Recombinant neutralizing secretory IgA antibodies for preventing mucosal acquisition and transmission of SARS-CoV-2Original Article Published on 2024-01-242024-09-05 Journal: Molecular therapy : the journal of the American So [Category] update2024, [키워드] molecular pharming monoclonal antibodies mucosal antibodies Nicotiana benthamiana passive immunization SARS-CoV-2 secretory IgA topical delivery Virus neutralization [DOI] 10.1016/j.ymthe.2024.01.025 PMC 바로가기 [Article Type] Original Article
A fast and easy one-step purification strategy for plant-made antibodies using Protein A magnetic beadsPlant Science Methods Published on 2024-01-032024-09-05 Journal: Frontiers in Plant Science [Category] update2024, [키워드] COVID - 19 magnetic bead purification monoclonal antibody Nicotiana benthamiana plant molecular farming [DOI] 10.3389/fpls.2023.1276148 PMC 바로가기 [Article Type] Plant Science Methods
Preclinical evaluation of immunogenicity, efficacy and safety of a recombinant plant-based SARS-CoV-2 RBD vaccine formulated with 3M-052-Alum adjuvantArticle Published on 2023-03-212024-09-05 Journal: Vaccine [Category] update2024, [키워드] COVID-19 neutralizing antibody Nicotiana benthamiana Plant-produced subunit vaccine Receptor binding domain SARS-CoV-2 [DOI] 10.1016/j.vaccine.2023.03.027 PMC 바로가기 [Article Type] Article
The “humanized” N‐glycosylation pathway in CRISPR /Cas9‐edited Nicotiana benthamiana significantly enhances the immunogenicity of a S/ preS1 Hepatitis B Virus antigen and the virus‐neutralizing antibody response in vaccinated miceResearch Article Published on 2023-03-102024-09-05 Journal: Plant Biotechnology Journal [Category] update2024, [키워드] CRISPR/Cas9 FX‐KO HBV HBV vaccine Nicotiana benthamiana plant N‐glycosylation [DOI] 10.1111/pbi.14028 PMC 바로가기 [Article Type] Research Article
Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen applicability applied approach Cellulose Concentration COVID-19 diagnosis CR3022 detect diagnostic Differential pulse voltammetry expressed functional group limit of detection linear relationship monoclonal antibody nasopharyngeal swab sample Nicotiana benthamiana Paper-based electrochemical immunosensor Plant-based antibody platform point-of-care pulse quantification RBD Receptor binding domain Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection Spike protein the RBD this system was performed [DOI] 10.1016/j.talanta.2022.123783 PMC 바로가기
SARS-CoV-2 spike trimer vaccine expressed in Nicotiana benthamiana adjuvanted with Alum elicits protective immune responses in miceArticle Published on 2022-12-012023-07-10 Journal: Plant Biotechnology Journal [Category] COVID19(2023년), [키워드] Immunity molecular farming Nicotiana benthamiana SARS-CoV-2 spike Vaccine [DOI] 10.1111/pbi.13908 PMC 바로가기