In vivo experimentally study the effect of Nigella Sativa silver nanoparticles for treatment of salmonella species causing diarrhea in ruminantsarticle Published on 2023-07-312024-09-01 Journal: Microbial Pathogenesis [Category] 살모넬라증, [키워드] in vivo Nigella Sativa Salmonella Silver nanoparticles [Article Type] article
Effect of black seeds (Nigella sativa) on inflammatory and immunomodulatory markers in Plasmodium berghei-infected miceArticle Published on 2022-11-302024-09-10 Journal: J Food Biochem [Category] 말라리아, [키워드] Anti-inflammation antibodies Cytokines immunomodulation Nigella Sativa PMC 바로가기
The Effect of Short Treatment with Nigella Sativa on Symptoms, the Cluster of Differentiation (CD) Profile, and Inflammatory Markers in Mild COVID-19 Patients: A Randomized, Double-Blind Controlled TrialArticle Published on 2022-09-192022-11-16 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] age Analysis Anti-inflammatory Asymptomatic Cluster control group Controlled Course COVID-19 COVID-19 cases demonstrated different dose differentiation disease dose double-blind Effect Final FIVE Gender group groups Inflammatory Inflammatory marker Intervention investigated marker Mild mild COVID-19 Nigella Nigella Sativa parameter Patient patients with COVID-19 placebo-controlled clinical trial procalcitonin profile randomized clinical trial Randomly SARS-COV-2 infection Saudi Arabia Seven significant difference significant effect subject Symptoms Treatment WBC were assessed while [DOI] 10.3390/ijerph191811798 PMC 바로가기
In Silico Studies on Zinc Oxide Based Nanostructured Oil Carriers with Seed Extracts of Nigella sativa and Pimpinella anisum as Potential Inhibitors of 3CL Protease of SARS-CoV-2SARS-CoV-2의 3CL 프로테아제의 잠재적 억제제로서 Nigella sativa 및 Pimpinella anisum의 종자 추출물을 포함하는 산화아연 기반 나노구조 오일 운반체에 대한 실리코 연구Article Published on 2022-07-042022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 변종, [키워드] 3CL 3CLpro acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition applicability candidate carrier characterized clinical trials Compound compounds conformational change coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 docking explained Extract Health histogram imperative inhibitor investigated Ligand ligands MD simulation mixture molecular molecular docking molecular docking studies molecular dynamic simulation molecular dynamics Molecular dynamics simulation MPro nanostructure Nigella Nigella Sativa Oil oleuropein Oxide pandemic Pimpenella anisum Potential protease Protein Research RMSD RMSF SARS-CoV-2 SARS-CoV-2 main protease seed selected stability structural proteins the SARS-CoV-2 trajectory Vaccines variant Zinc zinc oxide zinc oxide nanoparticles [DOI] 10.3390/molecules27134301 PMC 바로가기 [Article Type] Article
Virtual screening of phytoconstituents from miracle herb nigella sativa targeting nucleocapsid protein and papain-like protease of SARS-CoV-2 for COVID-19 treatmentArticle Published on 2022-06-012023-07-06 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, [키워드] molecular chemoinformatics Nigella Sativa nucleocapsid protein Papain-like protease phytocomponents. SARS-CoV-2 [DOI] 10.1080/07391102.2020.1852117 PMC 바로가기
In vitro potential antiviral SARS-CoV-19- activity of natural product thymohydroquinone and dithymoquinone from Nigella sativaNigella sativa의 천연물 티모하이드로퀴논 및 디티모퀴논의 시험관 내 잠재적 항바이러스 SARS-CoV-19- 활성Article Published on 2022-03-012022-09-11 Journal: Bioorganic chemistry [Category] SARS, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome Anti-SARS-CoV-2 Activity Antiviral antiviral activity assist calculated can be used Compound compounds Concentration coronavirus COVID-19 cytotoxicity Dithymoquinone essential oil Hydrothymoquinone IC50 Immunity in vitro MTT Nigella Nigella Sativa Oxidation protocol respiratory distress SARSCoV-19 selectivity index syndrome thymoquinone Treatment Vitamin E Zinc [DOI] 10.1016/j.bioorg.2021.105587 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Inhibitors from Nigella SativaArticle Published on 2022-03-012023-07-08 Journal: Applied biochemistry and biotechnology [Category] COVID19(2023년), [키워드] ADMET analysis in silico study Lipinski screening molecular docking Nigella Sativa SARS-CoV-2 [DOI] 10.1007/s12010-021-03790-8 PMC 바로가기
Prophylactic potential of honey and Nigella sativa L. against hospital and community-based SARS-CoV-2 spread: a structured summary of a study protocol for a randomised controlled trial병원 및 지역사회 기반 SARS-CoV-2 확산에 대한 꿀과 Nigella sativa L.의 예방 가능성: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-09-152022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 adaptive allergy analyst approved asymptomatic patient blinded Blinding body weight Botany Care care providers chronic infection clinic clinical Clinical management clinical study clinical trial college Community conflict conflict of interest control group coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19-related symptom COVID-19-related symptoms death defined dextrose dissemination doctor Efficacy element Endpoint enrolled evaluate excluded exposure to Final futility high risk Honey hospital hospitalizations incidence include institutional review board Intention interim analysis investigator management guidelines masking moderate National Health Service Nigella Nigella Sativa number objective outcome Pakistan parallel group participant Participants Patient patients per day Placebo placebo group placebo-controlled Primary outcome principal investigator Prophetic Medicine Prophylactic protocol randomisation randomised randomised controlled trial randomization Randomized receive recruited recruitment Registered reported responsible risk Sample size SARS-CoV-2 screened secondary Secondary endpoints severity Site Standard standard care Standardization status Stratification Study protocol supplementary material the patient therapeutic potential therapy Trial university Version water website [DOI] 10.1186/s13063-021-05510-3 PMC 바로가기 [Article Type] Letter
Indian Herb-Derived Phytoconstituent-Based Antiviral, Antimicrobial and Antifungal Formulation: An Oral Rinse Candidate for Oral Hygiene and the Potential Prevention of COVID-19 OutbreaksArticle Published on 2021-09-022022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] acute respiratory syndrome Antifungal antimicrobial Antiviral Antiviral agents antiviral drugs Asparagus Bacopa Bacterial candidate Chrysophanol circulating coronavirus Coronavirus-2 COVID-19 decrease effective Effectiveness FIVE gallic acid gargle growth Health HEK293T cells horizontal transmission inactivation Infectious disease ingredient inhibit lentiviral lung mammalian Mouthwash Multiple natural herb Nigella Sativa novel oral pandemic Phytoconstituents Plasmid Potential prevention question raising reduce reduced reducing respiratory viral infections rhein risk SARS-CoV-2 shedding susceptible Symptom tested topical treated Treatment triggered Vaccine variants of SARS-CoV-2 Viral load Viral transmission virucidal virus yeast cell [DOI] 10.3390/pathogens10091130 PMC 바로가기 [Article Type] Article
GENERATING RESPONSES IMMUNE IN CELLULAR AND HUMORAL TREATMENT WITH EPITOPE SPIKE, EPITOPE ENVELOPE PROTEIN, AND EPITOPE MEMBRANE PROTEIN SARS-COV-2, HONEY, SAUSSUREA LAPPA , AND NIGELLA SATIVA에피토프 스파이크, 에피토프 봉투 단백질 및 에피토프 막 단백질 SARS-COV-2, Honey, Saussurea Lappa 및 Nigella Sativa로 세포 및 체액 처리에서 면역을 생성합니다.Article Published on 2021-09-012022-09-10 Journal: African Journal of Infectious Diseases [Category] 비임상, [키워드] Sausseria lappa administration animal model breath Cellular immune response cellular immune responses cellular immunity clinical trial COVID-19 CPE CTL domination envelope protein epitope evaluated four group four groups Honey humoral immune response Humoral immunity IgG IL-4 immune responses immunomodulator Indonesia lung marker material membrane protein mice mouth Nigella Sativa NK cell NK cells organ pandemic PBS Placebo Research Respons immune Spike protein TGF-β β-defensin [DOI] 10.21010/ajidv15i2S.3 PMC 바로가기 [Article Type] Article